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14 similar compounds to monomer 50351512

Compile data set for download or QSAR
Wt: 213.2
BDBM50300132
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Wt: 269.3
BDBM50351513
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Wt: 299.4
BDBM50351514
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Wt: 295.3
BDBM50351515
Wt: 433.3
BDBM50351504
Wt: 368.4
BDBM50351505
Wt: 354.4
BDBM50351506
Wt: 340.4
BDBM50351507
Wt: 227.3
BDBM50351508
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Wt: 255.3
BDBM50351509
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Wt: 325.4
BDBM50351510
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Wt: 241.2
BDBM50351511
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Wt: 283.4
BDBM50351252
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Wt: 388.8
BDBM50351249

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50300132,50351513,50351514,50351515,50351504,50351505,50351506,50351507,50351508,50351509,50351510,50351511,50351252,50351249   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351506
PNG
(CHEMBL1823934)
Show SMILES O=C(CCCCCCCCCN=C=S)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C17H26N2O4S/c20-14(12-16(21)19-15-9-11-23-17(15)22)8-6-4-2-1-3-5-7-10-18-13-24/h15H,1-12H2,(H,19,21)/t15-/m0/s1
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n/an/a 3.00E+4n/an/an/an/an/an/a



Rowan University

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa LasR


ACS Med Chem Lett 6: 162-7 (2015)


Article DOI: 10.1021/ml500459f
BindingDB Entry DOI: 10.7270/Q2CV4KF1
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50300132
PNG
(CHEMBL584972 | N-heptanoyl-L-homoserine lactone)
Show SMILES CCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C11H19NO3/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1
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n/an/a 5.15E+4n/an/an/an/an/an/a



Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL


Assay Description
Inhibition of Pseudomonas aeruginosa LasR


Eur J Med Chem 45: 608-15 (2010)


Article DOI: 10.1016/j.ejmech.2009.11.004
BindingDB Entry DOI: 10.7270/Q2ZC83SP
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351252
PNG
(CHEMBL8755)
Show SMILES CCCCCCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C16H29NO3/c1-2-3-4-5-6-7-8-9-10-11-15(18)17-14-12-13-20-16(14)19/h14H,2-13H2,1H3,(H,17,18)/t14-/m0/s1
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n/an/a 40n/an/an/an/an/an/a



Florida International University

Curated by ChEMBL


Assay Description
Inhibition of Pseudomonas aeruginosa LasR


Bioorg Med Chem 19: 5500-6 (2011)


Article DOI: 10.1016/j.bmc.2011.07.044
BindingDB Entry DOI: 10.7270/Q2QF8T7Q
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351504
PNG
(CHEMBL1823937)
Show SMILES BrCC(=O)NCCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C18H29BrN2O5/c19-13-17(24)20-10-7-5-3-1-2-4-6-8-14(22)12-16(23)21-15-9-11-26-18(15)25/h15H,1-13H2,(H,20,24)(H,21,23)/t15-/m0/s1
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n/an/a 1.00E+5n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa LasR receptor assessed as inhibition of bioluminescence by reporter gene assay


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351505
PNG
(CHEMBL1823935)
Show SMILES O=C(CCCCCCCCCCN=C=S)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C18H28N2O4S/c21-15(13-17(22)20-16-10-12-24-18(16)23)9-7-5-3-1-2-4-6-8-11-19-14-25/h16H,1-13H2,(H,20,22)/t16-/m0/s1
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n/an/a 4.52E+4n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa LasR receptor assessed as inhibition of bioluminescence by reporter gene assay


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351506
PNG
(CHEMBL1823934)
Show SMILES O=C(CCCCCCCCCN=C=S)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C17H26N2O4S/c20-14(12-16(21)19-15-9-11-23-17(15)22)8-6-4-2-1-3-5-7-10-18-13-24/h15H,1-12H2,(H,19,21)/t15-/m0/s1
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n/an/a 1.13E+5n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa LasR receptor assessed as inhibition of bioluminescence by reporter gene assay


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351507
PNG
(CHEMBL1823933)
Show SMILES O=C(CCCCCCCCN=C=S)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C16H24N2O4S/c19-13(7-5-3-1-2-4-6-9-17-12-23)11-15(20)18-14-8-10-22-16(14)21/h14H,1-11H2,(H,18,20)/t14-/m0/s1
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n/an/a 3.00E+5n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa LasR receptor assessed as inhibition of bioluminescence by reporter gene assay


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50351508
PNG
(CHEMBL259352)
Show SMILES CCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C12H21NO3/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)/t10-/m0/s1
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n/an/a 770n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri luxR receptor in presence of 5 uM 3-oxo-C6-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50351509
PNG
(CHEMBL8799)
Show SMILES CCCCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C14H25NO3/c1-2-3-4-5-6-7-8-9-13(16)15-12-10-11-18-14(12)17/h12H,2-11H2,1H3,(H,15,16)/t12-/m0/s1
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n/an/a 400n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri luxR receptor in presence of 5 uM 3-oxo-C6-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50300132
PNG
(CHEMBL584972 | N-heptanoyl-L-homoserine lactone)
Show SMILES CCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C11H19NO3/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1
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n/an/a 1.36E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri luxR receptor in presence of 5 uM 3-oxo-C6-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein traR


(Rhizobium radiobacter)
BDBM50351508
PNG
(CHEMBL259352)
Show SMILES CCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C12H21NO3/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)/t10-/m0/s1
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n/an/a 770n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Agrobacterium tumefaciens TraR receptor in presence of 100 nM 3-oxo-C8-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein traR


(Rhizobium radiobacter)
BDBM50351509
PNG
(CHEMBL8799)
Show SMILES CCCCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C14H25NO3/c1-2-3-4-5-6-7-8-9-13(16)15-12-10-11-18-14(12)17/h12H,2-11H2,1H3,(H,15,16)/t12-/m0/s1
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n/an/a 1.05E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Agrobacterium tumefaciens TraR receptor in presence of 100 nM 3-oxo-C8-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein traR


(Rhizobium radiobacter)
BDBM50300132
PNG
(CHEMBL584972 | N-heptanoyl-L-homoserine lactone)
Show SMILES CCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C11H19NO3/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1
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n/an/a 690n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Agrobacterium tumefaciens TraR receptor in presence of 100 nM 3-oxo-C8-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351252
PNG
(CHEMBL8755)
Show SMILES CCCCCCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C16H29NO3/c1-2-3-4-5-6-7-8-9-10-11-15(18)17-14-12-13-20-16(14)19/h14H,2-13H2,1H3,(H,17,18)/t14-/m0/s1
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n/an/an/an/a 40n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in absence of natural autoinducer


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351510
PNG
(CHEMBL8463)
Show SMILES CCCCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C18H31NO4/c1-2-3-4-5-6-7-8-9-10-11-15(20)14-17(21)19-16-12-13-23-18(16)22/h16H,2-14H2,1H3,(H,19,21)/t16-/m0/s1
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n/an/an/an/a 10n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in absence of natural autoinducer


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351508
PNG
(CHEMBL259352)
Show SMILES CCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C12H21NO3/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)/t10-/m0/s1
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n/an/a 1.75E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in presence of 7.5 nM natural auto-inducer 3-oxo-C12-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351509
PNG
(CHEMBL8799)
Show SMILES CCCCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C14H25NO3/c1-2-3-4-5-6-7-8-9-13(16)15-12-10-11-18-14(12)17/h12H,2-11H2,1H3,(H,15,16)/t12-/m0/s1
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n/an/a 250n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in presence of 7.5 nM natural auto-inducer 3-oxo-C12-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351511
PNG
(CHEMBL463321)
Show SMILES CCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C12H19NO4/c1-2-3-4-5-9(14)8-11(15)13-10-6-7-17-12(10)16/h10H,2-8H2,1H3,(H,13,15)/t10-/m0/s1
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n/an/a 110n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in presence of 7.5 nM natural auto-inducer 3-oxo-C12-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351252
PNG
(CHEMBL8755)
Show SMILES CCCCCCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C16H29NO3/c1-2-3-4-5-6-7-8-9-10-11-15(18)17-14-12-13-20-16(14)19/h14H,2-13H2,1H3,(H,17,18)/t14-/m0/s1
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n/an/an/an/a 33n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351511
PNG
(CHEMBL463321)
Show SMILES CCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C12H19NO4/c1-2-3-4-5-9(14)8-11(15)13-10-6-7-17-12(10)16/h10H,2-8H2,1H3,(H,13,15)/t10-/m0/s1
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n/an/an/an/a 150n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351510
PNG
(CHEMBL8463)
Show SMILES CCCCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C18H31NO4/c1-2-3-4-5-6-7-8-9-10-11-15(20)14-17(21)19-16-12-13-23-18(16)22/h16H,2-14H2,1H3,(H,19,21)/t16-/m0/s1
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n/an/an/an/a 15n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351513
PNG
(CHEMBL8450)
Show SMILES CCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C14H23NO4/c1-2-3-4-5-6-7-11(16)10-13(17)15-12-8-9-19-14(12)18/h12H,2-10H2,1H3,(H,15,17)/t12-/m0/s1
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351514
PNG
(CHEMBL8609)
Show SMILES CCCCCCCCCC(O)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C16H29NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h13-14,18H,2-12H2,1H3,(H,17,19)/t13?,14-/m0/s1
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n/an/an/an/a 54n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351515
PNG
(CHEMBL1823932)
Show SMILES CCCCC\C=C\CCC(=O)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C16H25NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h6-7,14H,2-5,8-12H2,1H3,(H,17,19)/b7-6+/t14-/m0/s1
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n/an/an/an/a 10n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
PhzR


(Pseudomonas aeruginosa)
BDBM50351511
PNG
(CHEMBL463321)
Show SMILES CCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C12H19NO4/c1-2-3-4-5-9(14)8-11(15)13-10-6-7-17-12(10)16/h10H,2-8H2,1H3,(H,13,15)/t10-/m0/s1
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n/an/an/an/a 11n/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Agonist activity at Pseudomonas aeruginosa QscR expressed in Escherichia coli assessed as production of beta-galactosidase


Bioorg Med Chem Lett 18: 3072-5 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.095
BindingDB Entry DOI: 10.7270/Q2MS3TM8
More data for this
Ligand-Target Pair
PhzR


(Pseudomonas aeruginosa)
BDBM50351252
PNG
(CHEMBL8755)
Show SMILES CCCCCCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C16H29NO3/c1-2-3-4-5-6-7-8-9-10-11-15(18)17-14-12-13-20-16(14)19/h14H,2-13H2,1H3,(H,17,18)/t14-/m0/s1
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n/an/an/an/a 5n/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Agonist activity at Pseudomonas aeruginosa QscR expressed in Escherichia coli assessed as production of beta-galactosidase


Bioorg Med Chem Lett 18: 3072-5 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.095
BindingDB Entry DOI: 10.7270/Q2MS3TM8
More data for this
Ligand-Target Pair
PhzR


(Pseudomonas aeruginosa)
BDBM50351509
PNG
(CHEMBL8799)
Show SMILES CCCCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C14H25NO3/c1-2-3-4-5-6-7-8-9-13(16)15-12-10-11-18-14(12)17/h12H,2-11H2,1H3,(H,15,16)/t12-/m0/s1
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n/an/an/an/a 6n/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Agonist activity at Pseudomonas aeruginosa QscR expressed in Escherichia coli assessed as production of beta-galactosidase


Bioorg Med Chem Lett 18: 3072-5 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.095
BindingDB Entry DOI: 10.7270/Q2MS3TM8
More data for this
Ligand-Target Pair
PhzR


(Pseudomonas aeruginosa)
BDBM50351510
PNG
(CHEMBL8463)
Show SMILES CCCCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C18H31NO4/c1-2-3-4-5-6-7-8-9-10-11-15(20)14-17(21)19-16-12-13-23-18(16)22/h16H,2-14H2,1H3,(H,19,21)/t16-/m0/s1
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n/an/an/an/a 78n/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Agonist activity at Pseudomonas aeruginosa QscR expressed in Escherichia coli assessed as production of beta-galactosidase


Bioorg Med Chem Lett 18: 3072-5 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.095
BindingDB Entry DOI: 10.7270/Q2MS3TM8
More data for this
Ligand-Target Pair
Transcriptional activator protein traR


(Rhizobium radiobacter)
BDBM50300132
PNG
(CHEMBL584972 | N-heptanoyl-L-homoserine lactone)
Show SMILES CCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C11H19NO3/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1
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n/an/a 130n/an/an/an/an/an/a



Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL


Assay Description
Inhibition of Agrobacterium tumefaciens TraR


Eur J Med Chem 45: 608-15 (2010)


Article DOI: 10.1016/j.ejmech.2009.11.004
BindingDB Entry DOI: 10.7270/Q2ZC83SP
More data for this
Ligand-Target Pair
Transcriptional activator protein lasR


(Pseudomonas aeruginosa)
BDBM50351249
PNG
(CHEMBL1818521)
Show SMILES ClCC(=O)NCCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C18H29ClN2O5/c19-13-17(24)20-10-7-5-3-1-2-4-6-8-14(22)12-16(23)21-15-9-11-26-18(15)25/h15H,1-13H2,(H,20,24)(H,21,23)/t15-/m0/s1
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n/an/a 1.10E+3n/an/an/an/an/an/a



Florida International University

Curated by ChEMBL


Assay Description
Inhibition of Pseudomonas aeruginosa LasR


Bioorg Med Chem 19: 5500-6 (2011)


Article DOI: 10.1016/j.bmc.2011.07.044
BindingDB Entry DOI: 10.7270/Q2QF8T7Q
More data for this
Ligand-Target Pair