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1 similar compounds to monomer 50310303

Wt: 432.4
BDBM50310302

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50310302   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X/antithrombin III


(Homo sapiens)
BDBM50310302
PNG
(CHEMBL611992 | N,N'-(butane-1,4-diyl)bis(3,4-dihyd...)
Show SMILES Oc1ccc(cc1O)S(=O)(=O)NCCCCNS(=O)(=O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C16H20N2O8S2/c19-13-5-3-11(9-15(13)21)27(23,24)17-7-1-2-8-18-28(25,26)12-4-6-14(20)16(22)10-12/h3-6,9-10,17-22H,1-2,7-8H2
PDB
MMDB

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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>3.00E+6n/an/an/an/an/an/a



Eastern Michigan University

Curated by ChEMBL


Assay Description
Inhibition of antithrombin-3 assessed as residual alpha-thrombin activity


Bioorg Med Chem Lett 20: 966-70 (2010)

More data for this
Ligand-Target Pair
Plasminogen activator inhibitor-1


(Homo sapiens (Human))
BDBM50310302
PNG
(CHEMBL611992 | N,N'-(butane-1,4-diyl)bis(3,4-dihyd...)
Show SMILES Oc1ccc(cc1O)S(=O)(=O)NCCCCNS(=O)(=O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C16H20N2O8S2/c19-13-5-3-11(9-15(13)21)27(23,24)17-7-1-2-8-18-28(25,26)12-4-6-14(20)16(22)10-12/h3-6,9-10,17-22H,1-2,7-8H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>3.00E+6n/an/an/an/an/an/a



Eastern Michigan University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PAI1 assessed as rate of AMC release after 30 mins


Bioorg Med Chem Lett 20: 966-70 (2010)

More data for this
Ligand-Target Pair