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8 similar compounds to monomer 50310923

Wt: 366.4
BDBM50310902
Wt: 380.4
BDBM50310907
Wt: 380.4
BDBM50310909
Wt: 352.4
BDBM50310912
Wt: 367.4
BDBM50310922
Wt: 395.5
BDBM50310924
Wt: 395.5
BDBM50310925
Wt: 351.4
BDBM50377449

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 50310902,50310907,50310909,50310912,50310922,50310924,50310925,50377449   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50377449
PNG
(CHEMBL264433)
Show SMILES O=C(c1cccs1)c1nc(NCc2ccccc2)nc2ccsc12
Show InChI InChI=1S/C18H13N3OS2/c22-16(14-7-4-9-23-14)15-17-13(8-10-24-17)20-18(21-15)19-11-12-5-2-1-3-6-12/h1-10H,11H2,(H,19,20,21)
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25n/an/an/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Binding affinity to human adenosine A2A receptor


Bioorg Med Chem Lett 18: 2916-9 (2008)

More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50377449
PNG
(CHEMBL264433)
Show SMILES O=C(c1cccs1)c1nc(NCc2ccccc2)nc2ccsc12
Show InChI InChI=1S/C18H13N3OS2/c22-16(14-7-4-9-23-14)15-17-13(8-10-24-17)20-18(21-15)19-11-12-5-2-1-3-6-12/h1-10H,11H2,(H,19,20,21)
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1.73E+3n/an/an/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Binding affinity to human adenosine A1 receptor


Bioorg Med Chem Lett 18: 2916-9 (2008)

More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50310925
PNG
(CHEMBL1081160 | US9120807, 7 | {6-dimethylamino-2-...)
Show SMILES CN(C)c1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-24(2)15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)23-19(22-13)21-11-12-5-3-7-20-10-12/h3-10H,11H2,1-2H3,(H,21,22,23)
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n/an/a 318n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


Citation and Details
More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50310924
PNG
(CHEMBL1080421 | US9120807, 8 | {6-Ethylamino-2-[(p...)
Show SMILES CCNc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-2-21-15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)24-19(23-13)22-11-12-5-3-7-20-10-12/h3-10,21H,2,11H2,1H3,(H,22,23,24)
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n/an/a 726n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


Citation and Details
More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50310922
PNG
(CHEMBL1080241 | US9120807, 9 | {6-Amino-2-[(pyridi...)
Show SMILES Nc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C17H13N5OS2/c18-13-7-11-16(25-13)14(15(23)12-4-2-6-24-12)22-17(21-11)20-9-10-3-1-5-19-8-10/h1-8H,9,18H2,(H,20,21,22)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


Citation and Details
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50310925
PNG
(CHEMBL1081160 | US9120807, 7 | {6-dimethylamino-2-...)
Show SMILES CN(C)c1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-24(2)15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)23-19(22-13)21-11-12-5-3-7-20-10-12/h3-10H,11H2,1-2H3,(H,21,22,23)
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n/an/a 6.5n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


Citation and Details
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50310924
PNG
(CHEMBL1080421 | US9120807, 8 | {6-Ethylamino-2-[(p...)
Show SMILES CCNc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-2-21-15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)24-19(23-13)22-11-12-5-3-7-20-10-12/h3-10,21H,2,11H2,1H3,(H,22,23,24)
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n/an/a 6.70n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


Citation and Details
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50310922
PNG
(CHEMBL1080241 | US9120807, 9 | {6-Amino-2-[(pyridi...)
Show SMILES Nc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C17H13N5OS2/c18-13-7-11-16(25-13)14(15(23)12-4-2-6-24-12)22-17(21-11)20-9-10-3-1-5-19-8-10/h1-8H,9,18H2,(H,20,21,22)
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n/an/a 7.10n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


Citation and Details
More data for this
Ligand-Target Pair
Adenosine receptor A3 (A3)


(Homo sapiens (Human))
BDBM50310925
PNG
(CHEMBL1081160 | US9120807, 7 | {6-dimethylamino-2-...)
Show SMILES CN(C)c1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-24(2)15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)23-19(22-13)21-11-12-5-3-7-20-10-12/h3-10H,11H2,1-2H3,(H,21,22,23)
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n/an/a 130n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


Citation and Details
More data for this
Ligand-Target Pair
Adenosine receptor A3 (A3)


(Homo sapiens (Human))
BDBM50310924
PNG
(CHEMBL1080421 | US9120807, 8 | {6-Ethylamino-2-[(p...)
Show SMILES CCNc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-2-21-15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)24-19(23-13)22-11-12-5-3-7-20-10-12/h3-10,21H,2,11H2,1H3,(H,22,23,24)
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n/an/a 37.3n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


Citation and Details
More data for this
Ligand-Target Pair
Adenosine receptor A3 (A3)


(Homo sapiens (Human))
BDBM50310922
PNG
(CHEMBL1080241 | US9120807, 9 | {6-Amino-2-[(pyridi...)
Show SMILES Nc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C17H13N5OS2/c18-13-7-11-16(25-13)14(15(23)12-4-2-6-24-12)22-17(21-11)20-9-10-3-1-5-19-8-10/h1-8H,9,18H2,(H,20,21,22)
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US Patent
n/an/a 233n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


Citation and Details
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50310902
PNG
((5-methylthiophen-2-yl)(2-(pyridin-3-ylmethylamino...)
Show SMILES Cc1ccc(s1)C(=O)c1nc(NCc2cccnc2)nc2ccsc12
Show InChI InChI=1S/C18H14N4OS2/c1-11-4-5-14(25-11)16(23)15-17-13(6-8-24-17)21-18(22-15)20-10-12-3-2-7-19-9-12/h2-9H,10H2,1H3,(H,20,21,22)
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n/an/a 55n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2B receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50310907
PNG
((2-(methyl(pyridin-3-ylmethyl)amino)thieno[3,2-d]p...)
Show SMILES CN(Cc1cccnc1)c1nc(C(=O)c2ccc(C)s2)c2sccc2n1
Show InChI InChI=1S/C19H16N4OS2/c1-12-5-6-15(26-12)17(24)16-18-14(7-9-25-18)21-19(22-16)23(2)11-13-4-3-8-20-10-13/h3-10H,11H2,1-2H3
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n/an/a 4.14E+3n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2B receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50310909
PNG
((5-methylthiophen-2-yl)(2-(1-(pyridin-3-yl)ethylam...)
Show SMILES CC(Nc1nc(C(=O)c2ccc(C)s2)c2sccc2n1)c1cccnc1
Show InChI InChI=1S/C19H16N4OS2/c1-11-5-6-15(26-11)17(24)16-18-14(7-9-25-18)22-19(23-16)21-12(2)13-4-3-8-20-10-13/h3-10,12H,1-2H3,(H,21,22,23)
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n/an/a 17n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2B receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50310912
PNG
((2-(pyridin-3-ylmethylamino)thieno[3,2-d]pyrimidin...)
Show SMILES O=C(c1cccs1)c1nc(NCc2cccnc2)nc2ccsc12
Show InChI InChI=1S/C17H12N4OS2/c22-15(13-4-2-7-23-13)14-16-12(5-8-24-16)20-17(21-14)19-10-11-3-1-6-18-9-11/h1-9H,10H2,(H,19,20,21)
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n/an/a 18n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2B receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50310922
PNG
(CHEMBL1080241 | US9120807, 9 | {6-Amino-2-[(pyridi...)
Show SMILES Nc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C17H13N5OS2/c18-13-7-11-16(25-13)14(15(23)12-4-2-6-24-12)22-17(21-11)20-9-10-3-1-5-19-8-10/h1-8H,9,18H2,(H,20,21,22)
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n/an/a 32n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2B receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50310924
PNG
(CHEMBL1080421 | US9120807, 8 | {6-Ethylamino-2-[(p...)
Show SMILES CCNc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-2-21-15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)24-19(23-13)22-11-12-5-3-7-20-10-12/h3-10,21H,2,11H2,1H3,(H,22,23,24)
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n/an/a 19n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2B receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))
BDBM50310925
PNG
(CHEMBL1081160 | US9120807, 7 | {6-dimethylamino-2-...)
Show SMILES CN(C)c1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-24(2)15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)23-19(22-13)21-11-12-5-3-7-20-10-12/h3-10H,11H2,1-2H3,(H,21,22,23)
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n/an/a 39n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2B receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50310902
PNG
((5-methylthiophen-2-yl)(2-(pyridin-3-ylmethylamino...)
Show SMILES Cc1ccc(s1)C(=O)c1nc(NCc2cccnc2)nc2ccsc12
Show InChI InChI=1S/C18H14N4OS2/c1-11-4-5-14(25-11)16(23)15-17-13(6-8-24-17)21-18(22-15)20-10-12-3-2-7-19-9-12/h2-9H,10H2,1H3,(H,20,21,22)
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n/an/a 990n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2A receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50310907
PNG
((2-(methyl(pyridin-3-ylmethyl)amino)thieno[3,2-d]p...)
Show SMILES CN(Cc1cccnc1)c1nc(C(=O)c2ccc(C)s2)c2sccc2n1
Show InChI InChI=1S/C19H16N4OS2/c1-12-5-6-15(26-12)17(24)16-18-14(7-9-25-18)21-19(22-16)23(2)11-13-4-3-8-20-10-13/h3-10H,11H2,1-2H3
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n/an/a 2.27E+3n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2A receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50310909
PNG
((5-methylthiophen-2-yl)(2-(1-(pyridin-3-yl)ethylam...)
Show SMILES CC(Nc1nc(C(=O)c2ccc(C)s2)c2sccc2n1)c1cccnc1
Show InChI InChI=1S/C19H16N4OS2/c1-11-5-6-15(26-11)17(24)16-18-14(7-9-25-18)22-19(23-16)21-12(2)13-4-3-8-20-10-13/h3-10,12H,1-2H3,(H,21,22,23)
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n/an/a 99n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2A receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50310912
PNG
((2-(pyridin-3-ylmethylamino)thieno[3,2-d]pyrimidin...)
Show SMILES O=C(c1cccs1)c1nc(NCc2cccnc2)nc2ccsc12
Show InChI InChI=1S/C17H12N4OS2/c22-15(13-4-2-7-23-13)14-16-12(5-8-24-16)20-17(21-14)19-10-11-3-1-6-18-9-11/h1-9H,10H2,(H,19,20,21)
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n/an/a 51n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2A receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50310922
PNG
(CHEMBL1080241 | US9120807, 9 | {6-Amino-2-[(pyridi...)
Show SMILES Nc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C17H13N5OS2/c18-13-7-11-16(25-13)14(15(23)12-4-2-6-24-12)22-17(21-11)20-9-10-3-1-5-19-8-10/h1-8H,9,18H2,(H,20,21,22)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2A receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50310924
PNG
(CHEMBL1080421 | US9120807, 8 | {6-Ethylamino-2-[(p...)
Show SMILES CCNc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-2-21-15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)24-19(23-13)22-11-12-5-3-7-20-10-12/h3-10,21H,2,11H2,1H3,(H,22,23,24)
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n/an/a 2.49E+3n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2A receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50310925
PNG
(CHEMBL1081160 | US9120807, 7 | {6-dimethylamino-2-...)
Show SMILES CN(C)c1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-24(2)15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)23-19(22-13)21-11-12-5-3-7-20-10-12/h3-10H,11H2,1-2H3,(H,21,22,23)
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n/an/a 1.42E+3n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human adeosine A2A receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 5945-9 (2009)

More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50310922
PNG
(CHEMBL1080241 | US9120807, 9 | {6-Amino-2-[(pyridi...)
Show SMILES Nc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C17H13N5OS2/c18-13-7-11-16(25-13)14(15(23)12-4-2-6-24-12)22-17(21-11)20-9-10-3-1-5-19-8-10/h1-8H,9,18H2,(H,20,21,22)
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US Patent
n/an/a 1.10E+3n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


Citation and Details
More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50310925
PNG
(CHEMBL1081160 | US9120807, 7 | {6-dimethylamino-2-...)
Show SMILES CN(C)c1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-24(2)15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)23-19(22-13)21-11-12-5-3-7-20-10-12/h3-10H,11H2,1-2H3,(H,21,22,23)
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n/an/a 19.4n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


Citation and Details
More data for this
Ligand-Target Pair
Adenosine receptors; A1 & A2a


(Homo sapiens (human))
BDBM50310924
PNG
(CHEMBL1080421 | US9120807, 8 | {6-Ethylamino-2-[(p...)
Show SMILES CCNc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-2-21-15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)24-19(23-13)22-11-12-5-3-7-20-10-12/h3-10,21H,2,11H2,1H3,(H,22,23,24)
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US Patent
n/an/a 118n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


Citation and Details
More data for this
Ligand-Target Pair