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6 similar compounds to monomer 50321957

Compile data set for download or QSAR
Wt: 309.3
BDBM50321953
Wt: 325.3
BDBM50321954
Wt: 329.7
BDBM50321956
Wt: 352.3
BDBM50321963
Wt: 375.2
BDBM50321969
Wt: 339.3
BDBM50321975

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50321953,50321954,50321956,50321963,50321969,50321975   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50321956
PNG
(CHEMBL1173114 | N-(4-Chlorophenyl)-2-(piperazin-1-...)
Show SMILES Clc1ccc(Nc2nc(nc3nc[nH]c23)N2CCNCC2)cc1
Show InChI InChI=1S/C15H16ClN7/c16-10-1-3-11(4-2-10)20-14-12-13(19-9-18-12)21-15(22-14)23-7-5-17-6-8-23/h1-4,9,17H,5-8H2,(H2,18,19,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.18E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition cSRC


Bioorg Med Chem 18: 4615-24 (2011)


Article DOI: 10.1016/j.bmc.2010.05.032
BindingDB Entry DOI: 10.7270/Q26H4JCQ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50321963
PNG
(CHEMBL1173311 | N-(4-Acetamidophenyl)-2-(piperazin...)
Show SMILES CC(=O)Nc1ccc(Nc2nc(nc3nc[nH]c23)N2CCNCC2)cc1
Show InChI InChI=1S/C17H20N8O/c1-11(26)21-12-2-4-13(5-3-12)22-16-14-15(20-10-19-14)23-17(24-16)25-8-6-18-7-9-25/h2-5,10,18H,6-9H2,1H3,(H,21,26)(H2,19,20,22,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.05E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition cSRC


Bioorg Med Chem 18: 4615-24 (2011)


Article DOI: 10.1016/j.bmc.2010.05.032
BindingDB Entry DOI: 10.7270/Q26H4JCQ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50321954
PNG
(CHEMBL1173735 | N-(4-Methoxyphenyl)-2-(piperazin-1...)
Show SMILES COc1ccc(Nc2nc(nc3nc[nH]c23)N2CCNCC2)cc1
Show InChI InChI=1S/C16H19N7O/c1-24-12-4-2-11(3-5-12)20-15-13-14(19-10-18-13)21-16(22-15)23-8-6-17-7-9-23/h2-5,10,17H,6-9H2,1H3,(H2,18,19,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.43E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition cSRC


Bioorg Med Chem 18: 4615-24 (2011)


Article DOI: 10.1016/j.bmc.2010.05.032
BindingDB Entry DOI: 10.7270/Q26H4JCQ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50321975
PNG
(CHEMBL1173660 | N-Phenyl-2-(4-(2-hydroxyethyl)pipe...)
Show SMILES OCCN1CCN(CC1)c1nc(Nc2ccccc2)c2[nH]cnc2n1
Show InChI InChI=1S/C17H21N7O/c25-11-10-23-6-8-24(9-7-23)17-21-15-14(18-12-19-15)16(22-17)20-13-4-2-1-3-5-13/h1-5,12,25H,6-11H2,(H2,18,19,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.14E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition cSRC


Bioorg Med Chem 18: 4615-24 (2011)


Article DOI: 10.1016/j.bmc.2010.05.032
BindingDB Entry DOI: 10.7270/Q26H4JCQ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50321953
PNG
(CHEMBL1173736 | N-(3-Methylphenyl)-2-(piperazin-1-...)
Show SMILES Cc1cccc(Nc2nc(nc3nc[nH]c23)N2CCNCC2)c1
Show InChI InChI=1S/C16H19N7/c1-11-3-2-4-12(9-11)20-15-13-14(19-10-18-13)21-16(22-15)23-7-5-17-6-8-23/h2-4,9-10,17H,5-8H2,1H3,(H2,18,19,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.42E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition cSRC


Bioorg Med Chem 18: 4615-24 (2011)


Article DOI: 10.1016/j.bmc.2010.05.032
BindingDB Entry DOI: 10.7270/Q26H4JCQ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50321969
PNG
(CHEMBL1173552 | N-(4-Bromophenyl)-2-morpholino-9H-...)
Show SMILES Brc1ccc(Nc2nc(nc3nc[nH]c23)N2CCOCC2)cc1
Show InChI InChI=1S/C15H15BrN6O/c16-10-1-3-11(4-2-10)19-14-12-13(18-9-17-12)20-15(21-14)22-5-7-23-8-6-22/h1-4,9H,5-8H2,(H2,17,18,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 450n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition cSRC


Bioorg Med Chem 18: 4615-24 (2011)


Article DOI: 10.1016/j.bmc.2010.05.032
BindingDB Entry DOI: 10.7270/Q26H4JCQ
More data for this
Ligand-Target Pair