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5 similar compounds to monomer 50329417

Wt: 263.2
BDBM50329418
Wt: 281.2
BDBM50329425
Wt: 277.3
BDBM50329431
Wt: 281.2
BDBM50329415
Wt: 281.2
BDBM50329416

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50329418,50329425,50329431,50329415,50329416   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cell division cycle 7-related protein kinase


(Homo sapiens (Human))
BDBM50329415
PNG
(2-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccc(F)cc1)-c1ccncc1
Show InChI InChI=1S/C16H12FN3O/c17-12-3-1-11(2-4-12)15-13(16(18)21)9-14(20-15)10-5-7-19-8-6-10/h1-9,20H,(H2,18,21)
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PubMed
n/an/a 14n/an/an/an/an/an/a



Nerviano Medical Sciences Srl

Curated by ChEMBL


Assay Description
Inhibition of Cdc7


J Med Chem 53: 7296-315 (2010)

More data for this
Ligand-Target Pair
Cell division cycle 7-related protein kinase


(Homo sapiens (Human))
BDBM50329431
PNG
(5-Pyridin-4-yl-2-p-tolyl-1H-pyrrole-3-carboxamide ...)
Show SMILES Cc1ccc(cc1)-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C17H15N3O/c1-11-2-4-13(5-3-11)16-14(17(18)21)10-15(20-16)12-6-8-19-9-7-12/h2-10,20H,1H3,(H2,18,21)
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PubMed
n/an/a 6n/an/an/an/an/an/a



Nerviano Medical Sciences Srl

Curated by ChEMBL


Assay Description
Inhibition of Cdc7


J Med Chem 53: 7296-315 (2010)

More data for this
Ligand-Target Pair
Cell division cycle 7-related protein kinase


(Homo sapiens (Human))
BDBM50329425
PNG
(2-(3-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)
Show SMILES NC(=O)c1cc([nH]c1-c1cccc(F)c1)-c1ccncc1
Show InChI InChI=1S/C16H12FN3O/c17-12-3-1-2-11(8-12)15-13(16(18)21)9-14(20-15)10-4-6-19-7-5-10/h1-9,20H,(H2,18,21)
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PubMed
n/an/a 23n/an/an/an/an/an/a



Nerviano Medical Sciences Srl

Curated by ChEMBL


Assay Description
Inhibition of Cdc7


J Med Chem 53: 7296-315 (2010)

More data for this
Ligand-Target Pair
Cell division cycle 7-related protein kinase


(Homo sapiens (Human))
BDBM50329416
PNG
(2-(2-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1F)-c1ccncc1
Show InChI InChI=1S/C16H12FN3O/c17-13-4-2-1-3-11(13)15-12(16(18)21)9-14(20-15)10-5-7-19-8-6-10/h1-9,20H,(H2,18,21)
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PubMed
n/an/a 8n/an/an/an/an/an/a



Nerviano Medical Sciences Srl

Curated by ChEMBL


Assay Description
Inhibition of Cdc7


J Med Chem 53: 7296-315 (2010)

More data for this
Ligand-Target Pair
Cdc7 Kinase


(Homo sapiens (human))
BDBM50329431
PNG
(5-Pyridin-4-yl-2-p-tolyl-1H-pyrrole-3-carboxamide ...)
Show SMILES Cc1ccc(cc1)-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C17H15N3O/c1-11-2-4-13(5-3-11)16-14(17(18)21)10-15(20-16)12-6-8-19-9-7-12/h2-10,20H,1H3,(H2,18,21)
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US Patent
n/an/a<100n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...


Citation and Details
More data for this
Ligand-Target Pair
Cdc7 Kinase


(Homo sapiens (human))
BDBM50329418
PNG
(2-Phenyl-5-pyridin-4-yl-1H-pyrrole-3-carboxamide |...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1)-c1ccncc1
Show InChI InChI=1S/C16H13N3O/c17-16(20)13-10-14(11-6-8-18-9-7-11)19-15(13)12-4-2-1-3-5-12/h1-10,19H,(H2,17,20)
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US Patent
n/an/a<100n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...


Citation and Details
More data for this
Ligand-Target Pair
Cdc7 Kinase


(Homo sapiens (human))
BDBM50329416
PNG
(2-(2-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1F)-c1ccncc1
Show InChI InChI=1S/C16H12FN3O/c17-13-4-2-1-3-11(13)15-12(16(18)21)9-14(20-15)10-5-7-19-8-6-10/h1-9,20H,(H2,18,21)
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US Patent
n/an/a<100n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...


Citation and Details
More data for this
Ligand-Target Pair
Cdc7 Kinase


(Homo sapiens (human))
BDBM50329425
PNG
(2-(3-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)
Show SMILES NC(=O)c1cc([nH]c1-c1cccc(F)c1)-c1ccncc1
Show InChI InChI=1S/C16H12FN3O/c17-12-3-1-2-11(8-12)15-13(16(18)21)9-14(20-15)10-4-6-19-7-5-10/h1-9,20H,(H2,18,21)
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US Patent
n/an/a<100n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...


Citation and Details
More data for this
Ligand-Target Pair
Cdc7 Kinase


(Homo sapiens (human))
BDBM50329415
PNG
(2-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccc(F)cc1)-c1ccncc1
Show InChI InChI=1S/C16H12FN3O/c17-12-3-1-11(2-4-12)15-13(16(18)21)9-14(20-15)10-5-7-19-8-6-10/h1-9,20H,(H2,18,21)
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US Patent
n/an/a<100n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...


Citation and Details
More data for this
Ligand-Target Pair
Cell division cycle 7-related protein kinase


(Homo sapiens (Human))
BDBM50329418
PNG
(2-Phenyl-5-pyridin-4-yl-1H-pyrrole-3-carboxamide |...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1)-c1ccncc1
Show InChI InChI=1S/C16H13N3O/c17-16(20)13-10-14(11-6-8-18-9-7-11)19-15(13)12-4-2-1-3-5-12/h1-10,19H,(H2,17,20)
PDB

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PubMed
n/an/a 9n/an/an/an/an/an/a



Nerviano Medical Sciences Srl

Curated by ChEMBL


Assay Description
Inhibition of Cdc7


J Med Chem 53: 7296-315 (2010)

More data for this
Ligand-Target Pair