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30 similar compounds to monomer 50437999

Compile data set for download or QSAR
Wt: 294.3
BDBM50349389
Wt: 308.3
BDBM50349390
Wt: 294.3
BDBM50349407
Wt: 308.3
BDBM50349409
Wt: 308.3
BDBM50349410
Wt: 309.3
BDBM50349418
Wt: 280.2
BDBM50349419
Wt: 308.3
BDBM50349420
Wt: 322.3
BDBM50349424
Wt: 322.3
BDBM50349441
Wt: 339.3
BDBM50437992
Wt: 379.4
BDBM50437994
Wt: 365.3
BDBM50437995
Wt: 345.3
BDBM50437996
Wt: 369.3
BDBM50437997
Displayed 1 to 15 (of 30 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50349389,50349390,50349407,50349409,50349410,50349418,50349419,50349420,50349424,50349441,50437992,50437994,50437995,50437996,50437997   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-chymotrypsin


(Homo sapiens (Human))
BDBM50437992
PNG
(CHEMBL2409445)
Show SMILES COC(=O)c1nn(C(=O)c2cccc(C)c2)c2cc(ccc12)[N+]([O-])=O
Show InChI InChI=1S/C17H13N3O5/c1-10-4-3-5-11(8-10)16(21)19-14-9-12(20(23)24)6-7-13(14)15(18-19)17(22)25-2/h3-9H,1-2H3
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n/an/a 38n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysis


J Med Chem 56: 6259-72 (2013)


Article DOI: 10.1021/jm400742j
BindingDB Entry DOI: 10.7270/Q2MC91FN
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50349441
PNG
(CHEMBL1808519)
Show SMILES CCCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccccc12
Show InChI InChI=1S/C19H18N2O3/c1-3-11-24-19(23)17-15-9-4-5-10-16(15)21(20-17)18(22)14-8-6-7-13(2)12-14/h4-10,12H,3,11H2,1-2H3
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n/an/a 780n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methyl-coumarin as substrate measured every 30 secs for 10 m...


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Beta-chymotrypsin


(Homo sapiens (Human))
BDBM50437995
PNG
(CHEMBL2409570)
Show SMILES CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc(NC(C)=O)cc12
Show InChI InChI=1S/C20H19N3O4/c1-4-27-20(26)18-16-11-15(21-13(3)24)8-9-17(16)23(22-18)19(25)14-7-5-6-12(2)10-14/h5-11H,4H2,1-3H3,(H,21,24)
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n/an/a 170n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysis


J Med Chem 56: 6259-72 (2013)


Article DOI: 10.1021/jm400742j
BindingDB Entry DOI: 10.7270/Q2MC91FN
More data for this
Ligand-Target Pair
Beta-chymotrypsin


(Homo sapiens (Human))
BDBM50437996
PNG
(CHEMBL2409458)
Show SMILES CCOC(=O)c1nn(C(=O)c2ccsc2)c2ccc(cc12)[N+]([O-])=O
Show InChI InChI=1S/C15H11N3O5S/c1-2-23-15(20)13-11-7-10(18(21)22)3-4-12(11)17(16-13)14(19)9-5-6-24-8-9/h3-8H,2H2,1H3
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n/an/a 46n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysis


J Med Chem 56: 6259-72 (2013)


Article DOI: 10.1021/jm400742j
BindingDB Entry DOI: 10.7270/Q2MC91FN
More data for this
Ligand-Target Pair
Beta-chymotrypsin


(Homo sapiens (Human))
BDBM50437997
PNG
(CHEMBL2409457)
Show SMILES CCOC(=O)c1nn(C(=O)c2cccc(OC)c2)c2ccc(cc12)[N+]([O-])=O
Show InChI InChI=1S/C18H15N3O6/c1-3-27-18(23)16-14-10-12(21(24)25)7-8-15(14)20(19-16)17(22)11-5-4-6-13(9-11)26-2/h4-10H,3H2,1-2H3
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n/an/a 21n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysis


J Med Chem 56: 6259-72 (2013)


Article DOI: 10.1021/jm400742j
BindingDB Entry DOI: 10.7270/Q2MC91FN
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50437992
PNG
(CHEMBL2409445)
Show SMILES COC(=O)c1nn(C(=O)c2cccc(C)c2)c2cc(ccc12)[N+]([O-])=O
Show InChI InChI=1S/C17H13N3O5/c1-10-4-3-5-11(8-10)16(21)19-14-9-12(20(23)24)6-7-13(14)15(18-19)17(22)25-2/h3-9H,1-2H3
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n/an/a 20n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methylcoumarin as substrate measured every 30 seconds for 10...


J Med Chem 56: 6259-72 (2013)


Article DOI: 10.1021/jm400742j
BindingDB Entry DOI: 10.7270/Q2MC91FN
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50437994
PNG
(CHEMBL2409571)
Show SMILES CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc(NC(=O)CC)cc12
Show InChI InChI=1S/C21H21N3O4/c1-4-18(25)22-15-9-10-17-16(12-15)19(21(27)28-5-2)23-24(17)20(26)14-8-6-7-13(3)11-14/h6-12H,4-5H2,1-3H3,(H,22,25)
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n/an/a 18n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methylcoumarin as substrate measured every 30 seconds for 10...


J Med Chem 56: 6259-72 (2013)


Article DOI: 10.1021/jm400742j
BindingDB Entry DOI: 10.7270/Q2MC91FN
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50437995
PNG
(CHEMBL2409570)
Show SMILES CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc(NC(C)=O)cc12
Show InChI InChI=1S/C20H19N3O4/c1-4-27-20(26)18-16-11-15(21-13(3)24)8-9-17(16)23(22-18)19(25)14-7-5-6-12(2)10-14/h5-11H,4H2,1-3H3,(H,21,24)
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n/an/a 30n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methylcoumarin as substrate measured every 30 seconds for 10...


J Med Chem 56: 6259-72 (2013)


Article DOI: 10.1021/jm400742j
BindingDB Entry DOI: 10.7270/Q2MC91FN
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50437996
PNG
(CHEMBL2409458)
Show SMILES CCOC(=O)c1nn(C(=O)c2ccsc2)c2ccc(cc12)[N+]([O-])=O
Show InChI InChI=1S/C15H11N3O5S/c1-2-23-15(20)13-11-7-10(18(21)22)3-4-12(11)17(16-13)14(19)9-5-6-24-8-9/h3-8H,2H2,1H3
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n/an/a 30n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methylcoumarin as substrate measured every 30 seconds for 10...


J Med Chem 56: 6259-72 (2013)


Article DOI: 10.1021/jm400742j
BindingDB Entry DOI: 10.7270/Q2MC91FN
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50437997
PNG
(CHEMBL2409457)
Show SMILES CCOC(=O)c1nn(C(=O)c2cccc(OC)c2)c2ccc(cc12)[N+]([O-])=O
Show InChI InChI=1S/C18H15N3O6/c1-3-27-18(23)16-14-10-12(21(24)25)7-8-15(14)20(19-16)17(22)11-5-4-6-13(9-11)26-2/h4-10H,3H2,1-2H3
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n/an/a 25n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methylcoumarin as substrate measured every 30 seconds for 10...


J Med Chem 56: 6259-72 (2013)


Article DOI: 10.1021/jm400742j
BindingDB Entry DOI: 10.7270/Q2MC91FN
More data for this
Ligand-Target Pair
Thrombin and coagulation factor X


(Homo sapiens (Human))
BDBM50349389
PNG
(CHEMBL1808514)
Show SMILES COC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccccc12
Show InChI InChI=1S/C17H14N2O3/c1-11-6-5-7-12(10-11)16(20)19-14-9-4-3-8-13(14)15(18-19)17(21)22-2/h3-10H,1-2H3
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n/an/a 5.10E+3n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human plasma thrombin benzoyl-Phe-Val-Arg-7-amino-4-methylcoumarin as substrate by spectrophotometric analysis


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Thrombin and coagulation factor X


(Homo sapiens (Human))
BDBM50349390
PNG
(CHEMBL1808523)
Show SMILES CC(C)OC(=O)c1nn(C(=O)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C18H16N2O3/c1-12(2)23-18(22)16-14-10-6-7-11-15(14)20(19-16)17(21)13-8-4-3-5-9-13/h3-12H,1-2H3
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n/an/a 7.80E+3n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human plasma thrombin benzoyl-Phe-Val-Arg-7-amino-4-methylcoumarin as substrate by spectrophotometric analysis


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50349389
PNG
(CHEMBL1808514)
Show SMILES COC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccccc12
Show InChI InChI=1S/C17H14N2O3/c1-11-6-5-7-12(10-11)16(20)19-14-9-4-3-8-13(14)15(18-19)17(21)22-2/h3-10H,1-2H3
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n/an/a 870n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human urine urokinase using benzyloxycarbonyl-Gly-Gly-Arg-7-amino-4-methylcoumarin as substrate by spectrophotometric analysis


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50349390
PNG
(CHEMBL1808523)
Show SMILES CC(C)OC(=O)c1nn(C(=O)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C18H16N2O3/c1-12(2)23-18(22)16-14-10-6-7-11-15(14)20(19-16)17(21)13-8-4-3-5-9-13/h3-12H,1-2H3
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n/an/a 6.30E+3n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human urine urokinase using benzyloxycarbonyl-Gly-Gly-Arg-7-amino-4-methylcoumarin as substrate by spectrophotometric analysis


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50349407
PNG
(CHEMBL1808494)
Show SMILES CCOC(=O)c1nn(C(=O)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C17H14N2O3/c1-2-22-17(21)15-13-10-6-7-11-14(13)19(18-15)16(20)12-8-4-3-5-9-12/h3-11H,2H2,1H3
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n/an/a 400n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methyl-coumarin as substrate measured every 30 secs for 10 m...


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50349409
PNG
(CHEMBL1808496)
Show SMILES CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccccc12
Show InChI InChI=1S/C18H16N2O3/c1-3-23-18(22)16-14-9-4-5-10-15(14)20(19-16)17(21)13-8-6-7-12(2)11-13/h4-11H,3H2,1-2H3
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n/an/a 410n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methyl-coumarin as substrate measured every 30 secs for 10 m...


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50349410
PNG
(CHEMBL1808497)
Show SMILES CCOC(=O)c1nn(C(=O)c2ccc(C)cc2)c2ccccc12
Show InChI InChI=1S/C18H16N2O3/c1-3-23-18(22)16-14-6-4-5-7-15(14)20(19-16)17(21)13-10-8-12(2)9-11-13/h4-11H,3H2,1-2H3
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n/an/a 3.60E+4n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methyl-coumarin as substrate measured every 30 secs for 10 m...


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50349418
PNG
(CHEMBL1808512)
Show SMILES CCOC(=O)c1nn(C(=O)c2cccc(N)c2)c2ccccc12
Show InChI InChI=1S/C17H15N3O3/c1-2-23-17(22)15-13-8-3-4-9-14(13)20(19-15)16(21)11-6-5-7-12(18)10-11/h3-10H,2,18H2,1H3
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n/an/a 1.60E+3n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methyl-coumarin as substrate measured every 30 secs for 10 m...


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50349419
PNG
(CHEMBL1808513)
Show SMILES COC(=O)c1nn(C(=O)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C16H12N2O3/c1-21-16(20)14-12-9-5-6-10-13(12)18(17-14)15(19)11-7-3-2-4-8-11/h2-10H,1H3
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n/an/a 89n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methyl-coumarin as substrate measured every 30 secs for 10 m...


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50349389
PNG
(CHEMBL1808514)
Show SMILES COC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccccc12
Show InChI InChI=1S/C17H14N2O3/c1-11-6-5-7-12(10-11)16(20)19-14-9-4-3-8-13(14)15(18-19)17(21)22-2/h3-10H,1-2H3
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n/an/a 130n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methyl-coumarin as substrate measured every 30 secs for 10 m...


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50349420
PNG
(CHEMBL1808518)
Show SMILES CCCOC(=O)c1nn(C(=O)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C18H16N2O3/c1-2-12-23-18(22)16-14-10-6-7-11-15(14)20(19-16)17(21)13-8-4-3-5-9-13/h3-11H,2,12H2,1H3
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n/an/a 400n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methyl-coumarin as substrate measured every 30 secs for 10 m...


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50349390
PNG
(CHEMBL1808523)
Show SMILES CC(C)OC(=O)c1nn(C(=O)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C18H16N2O3/c1-12(2)23-18(22)16-14-10-6-7-11-15(14)20(19-16)17(21)13-8-4-3-5-9-13/h3-12H,1-2H3
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n/an/a 240n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methyl-coumarin as substrate measured every 30 secs for 10 m...


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50349424
PNG
(CHEMBL1808524)
Show SMILES CC(C)OC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccccc12
Show InChI InChI=1S/C19H18N2O3/c1-12(2)24-19(23)17-15-9-4-5-10-16(15)21(20-17)18(22)14-8-6-7-13(3)11-14/h4-12H,1-3H3
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n/an/a 650n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methyl-coumarin as substrate measured every 30 secs for 10 m...


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Thrombin and coagulation factor X


(Homo sapiens (Human))
BDBM50349419
PNG
(CHEMBL1808513)
Show SMILES COC(=O)c1nn(C(=O)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C16H12N2O3/c1-21-16(20)14-12-9-5-6-10-13(12)18(17-14)15(19)11-7-3-2-4-8-11/h2-10H,1H3
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antibodypedia
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n/an/a 1.40E+4n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human plasma thrombin benzoyl-Phe-Val-Arg-7-amino-4-methylcoumarin as substrate by spectrophotometric analysis


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50349419
PNG
(CHEMBL1808513)
Show SMILES COC(=O)c1nn(C(=O)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C16H12N2O3/c1-21-16(20)14-12-9-5-6-10-13(12)18(17-14)15(19)11-7-3-2-4-8-11/h2-10H,1H3
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n/an/a 1.20E+3n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human urine urokinase using benzyloxycarbonyl-Gly-Gly-Arg-7-amino-4-methylcoumarin as substrate by spectrophotometric analysis


Bioorg Med Chem 19: 4460-72 (2011)


Article DOI: 10.1016/j.bmc.2011.06.036
BindingDB Entry DOI: 10.7270/Q2JD4X5N
More data for this
Ligand-Target Pair
Beta-chymotrypsin


(Homo sapiens (Human))
BDBM50437994
PNG
(CHEMBL2409571)
Show SMILES CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc(NC(=O)CC)cc12
Show InChI InChI=1S/C21H21N3O4/c1-4-18(25)22-15-9-10-17-16(12-15)19(21(27)28-5-2)23-24(17)20(26)14-8-6-7-13(3)11-14/h6-12H,4-5H2,1-3H3,(H,22,25)
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n/an/a 140n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysis


J Med Chem 56: 6259-72 (2013)


Article DOI: 10.1021/jm400742j
BindingDB Entry DOI: 10.7270/Q2MC91FN
More data for this
Ligand-Target Pair