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3 similar compounds to monomer 50040253

Wt: 415.4
BDBM50349937
Wt: 429.5
BDBM50349957
Wt: 429.5
BDBM50349964

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50349937,50349957,50349964   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349957
PNG
(CHEMBL1812292)
Show SMILES COc1ccccc1N1CCN(CCn2cnc3c4ccc(C)cc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H27N5O2/c1-18-7-8-19-21(15-18)26-16-20-24(19)27-17-30(25(20)31)14-11-28-9-12-29(13-10-28)22-5-3-4-6-23(22)32-2/h3-8,15-17H,9-14H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
14n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349937
PNG
(CHEMBL1812168)
Show SMILES COc1ccccc1N1CCN(CCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C24H25N5O2/c1-31-22-9-5-4-8-21(22)28-13-10-27(11-14-28)12-15-29-17-26-23-18-6-2-3-7-20(18)25-16-19(23)24(29)30/h2-9,16-17H,10-15H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
42n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349964
PNG
(CHEMBL1812303)
Show SMILES COc1ccccc1N1CCN(CCn2cnc3c4cc(C)ccc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H27N5O2/c1-18-7-8-21-19(15-18)24-20(16-26-21)25(31)30(17-27-24)14-11-28-9-12-29(13-10-28)22-5-3-4-6-23(22)32-2/h3-8,15-17H,9-14H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
82n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)

More data for this
Ligand-Target Pair