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7 similar compounds to monomer 50370021

Compile data set for download or QSAR
Wt: 178.2
BDBM50370028
Wt: 192.2
BDBM50370029
Wt: 178.2
BDBM50370030
Wt: 192.2
BDBM50370033
Wt: 192.2
BDBM50370037
Wt: 192.2
BDBM50370015
Wt: 220.3
BDBM50370016

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50370028,50370029,50370030,50370033,50370037,50370015,50370016   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1D adrenergic receptor


(Homo sapiens (Human))
BDBM50370037
PNG
(CHEMBL1744288)
Show SMILES CCc1sccc1Cc1cnc[nH]1
Show InChI InChI=1S/C10H12N2S/c1-2-10-8(3-4-13-10)5-9-6-11-7-12-9/h3-4,6-7H,2,5H2,1H3,(H,11,12)
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Article
PubMed
0.0700n/an/an/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against alpha-2D adrenergic receptor of male Wistar rat


J Med Chem 44: 863-72 (2001)


Article DOI: 10.1021/jm0003891
BindingDB Entry DOI: 10.7270/Q23R0TKP
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))
BDBM50370033
PNG
(CHEMBL1744278)
Show SMILES CCc1cscc1Cc1cnc[nH]1
Show InChI InChI=1S/C10H12N2S/c1-2-8-5-13-6-9(8)3-10-4-11-7-12-10/h4-7H,2-3H2,1H3,(H,11,12)
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Article
PubMed
0.290n/an/an/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against alpha-2D adrenergic receptor of male Wistar rat


J Med Chem 44: 863-72 (2001)


Article DOI: 10.1021/jm0003891
BindingDB Entry DOI: 10.7270/Q23R0TKP
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))
BDBM50370016
PNG
(CHEMBL1744276)
Show SMILES CCc1cc(Cc2cnc[nH]2)c(CC)s1
Show InChI InChI=1S/C12H16N2S/c1-3-11-6-9(12(4-2)15-11)5-10-7-13-8-14-10/h6-8H,3-5H2,1-2H3,(H,13,14)
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PubMed
0.400n/an/an/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against alpha-2D adrenergic receptor of male Wistar rat


J Med Chem 44: 863-72 (2001)


Article DOI: 10.1021/jm0003891
BindingDB Entry DOI: 10.7270/Q23R0TKP
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))
BDBM50370028
PNG
(CHEMBL1744294)
Show SMILES Cc1sccc1Cc1cnc[nH]1
Show InChI InChI=1S/C9H10N2S/c1-7-8(2-3-12-7)4-9-5-10-6-11-9/h2-3,5-6H,4H2,1H3,(H,10,11)
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PubMed
0.440n/an/an/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against alpha-2D adrenergic receptor of male Wistar rat


J Med Chem 44: 863-72 (2001)


Article DOI: 10.1021/jm0003891
BindingDB Entry DOI: 10.7270/Q23R0TKP
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))
BDBM50370030
PNG
(CHEMBL1744291)
Show SMILES Cc1cscc1Cc1cnc[nH]1
Show InChI InChI=1S/C9H10N2S/c1-7-4-12-5-8(7)2-9-3-10-6-11-9/h3-6H,2H2,1H3,(H,10,11)
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PubMed
0.470n/an/an/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against alpha-2D adrenergic receptor of male Wistar rat


J Med Chem 44: 863-72 (2001)


Article DOI: 10.1021/jm0003891
BindingDB Entry DOI: 10.7270/Q23R0TKP
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))
BDBM50370015
PNG
(CHEMBL1744277)
Show SMILES Cc1cc(Cc2cnc[nH]2)c(C)s1
Show InChI InChI=1S/C10H12N2S/c1-7-3-9(8(2)13-7)4-10-5-11-6-12-10/h3,5-6H,4H2,1-2H3,(H,11,12)
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Article
PubMed
0.690n/an/an/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against alpha-2D adrenergic receptor of male Wistar rat


J Med Chem 44: 863-72 (2001)


Article DOI: 10.1021/jm0003891
BindingDB Entry DOI: 10.7270/Q23R0TKP
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))
BDBM50370029
PNG
(CHEMBL1744269)
Show SMILES CC(c1cnc[nH]1)c1ccsc1C
Show InChI InChI=1S/C10H12N2S/c1-7(10-5-11-6-12-10)9-3-4-13-8(9)2/h3-7H,1-2H3,(H,11,12)
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Article
PubMed
2.30n/an/an/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against alpha-2D adrenergic receptor of male Wistar rat


J Med Chem 44: 863-72 (2001)


Article DOI: 10.1021/jm0003891
BindingDB Entry DOI: 10.7270/Q23R0TKP
More data for this
Ligand-Target Pair