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18 similar compounds to monomer 50376868

Compile data set for download or QSAR
Wt: 408.3
BDBM50376853
Purchase
Wt: 423.4
BDBM50376855
Wt: 453.3
BDBM50376856
Wt: 452.4
BDBM50376857
Wt: 453.3
BDBM50376858
Wt: 423.4
BDBM50376859
Wt: 438.4
BDBM50376860
Wt: 456.8
BDBM50376861
Wt: 453.3
BDBM50376862
Wt: 433.4
BDBM50376863
Wt: 423.4
BDBM50376864
Wt: 423.4
BDBM50376865
Wt: 487.2
BDBM50376866
Wt: 433.4
BDBM50376867
Wt: 442.8
BDBM50376869
Displayed 1 to 15 (of 18 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 34 hits for monomerid = 50376853,50376855,50376856,50376857,50376858,50376859,50376860,50376861,50376862,50376863,50376864,50376865,50376866,50376867,50376869   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376853
PNG
(CHEMBL258986)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F
Show InChI InChI=1/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376853
PNG
(CHEMBL258986)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F
Show InChI InChI=1/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27)
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n/an/a 1.25E+4n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376855
PNG
(CHEMBL412315)
Show SMILES Nc1cccc2c(c[nH]c12)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1/C18H16F3N5O2S/c19-18(20,21)16-8-15(13-9-24-17-12(13)2-1-3-14(17)22)26(25-16)10-4-6-11(7-5-10)29(23,27)28/h1-7,9,15,24H,8,22H2,(H2,23,27,28)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376856
PNG
(CHEMBL259881)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2c(cccc12)[N+]([O-])=O)C(F)(F)F
Show InChI InChI=1/C18H14F3N5O4S/c19-18(20,21)16-8-15(13-9-23-17-12(13)2-1-3-14(17)26(27)28)25(24-16)10-4-6-11(7-5-10)31(22,29)30/h1-7,9,15,23H,8H2,(H2,22,29,30)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376857
PNG
(CHEMBL412286)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccc(cc12)C(O)=O)C(F)(F)F
Show InChI InChI=1/C19H15F3N4O4S/c20-19(21,22)17-8-16(14-9-24-15-6-1-10(18(27)28)7-13(14)15)26(25-17)11-2-4-12(5-3-11)31(23,29)30/h1-7,9,16,24H,8H2,(H,27,28)(H2,23,29,30)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376858
PNG
(CHEMBL265200)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccc(cc12)[N+]([O-])=O)C(F)(F)F
Show InChI InChI=1/C18H14F3N5O4S/c19-18(20,21)17-8-16(14-9-23-15-6-3-11(26(27)28)7-13(14)15)25(24-17)10-1-4-12(5-2-10)31(22,29)30/h1-7,9,16,23H,8H2,(H2,22,29,30)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376859
PNG
(CHEMBL408971)
Show SMILES Nc1ccc2c(c[nH]c2c1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1/C18H16F3N5O2S/c19-18(20,21)17-8-16(14-9-24-15-7-10(22)1-6-13(14)15)26(25-17)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8,22H2,(H2,23,27,28)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376860
PNG
(CHEMBL411032)
Show SMILES COc1cccc2[nH]cc(C3CC(=NN3c3ccc(cc3)S(N)(=O)=O)C(F)(F)F)c12
Show InChI InChI=1/C19H17F3N4O3S/c1-29-16-4-2-3-14-18(16)13(10-24-14)15-9-17(19(20,21)22)25-26(15)11-5-7-12(8-6-11)30(23,27)28/h2-8,10,15,24H,9H2,1H3,(H2,23,27,28)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376861
PNG
(CHEMBL411719)
Show SMILES Cc1[nH]c2cc(Cl)ccc2c1C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1/C19H16ClF3N4O2S/c1-10-18(14-7-2-11(20)8-15(14)25-10)16-9-17(19(21,22)23)26-27(16)12-3-5-13(6-4-12)30(24,28)29/h2-8,16,25H,9H2,1H3,(H2,24,28,29)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376862
PNG
(CHEMBL258988)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2cc(ccc12)[N+]([O-])=O)C(F)(F)F
Show InChI InChI=1/C18H14F3N5O4S/c19-18(20,21)17-8-16(14-9-23-15-7-11(26(27)28)3-6-13(14)15)25(24-17)10-1-4-12(5-2-10)31(22,29)30/h1-7,9,16,23H,8H2,(H2,22,29,30)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376863
PNG
(CHEMBL263383)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2cc(ccc12)C#N)C(F)(F)F
Show InChI InChI=1/C19H14F3N5O2S/c20-19(21,22)18-8-17(15-10-25-16-7-11(9-23)1-6-14(15)16)27(26-18)12-2-4-13(5-3-12)30(24,28)29/h1-7,10,17,25H,8H2,(H2,24,28,29)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376864
PNG
(CHEMBL263640)
Show SMILES Nc1cccc2[nH]cc(C3CC(=NN3c3ccc(cc3)S(N)(=O)=O)C(F)(F)F)c12
Show InChI InChI=1/C18H16F3N5O2S/c19-18(20,21)16-8-15(12-9-24-14-3-1-2-13(22)17(12)14)26(25-16)10-4-6-11(7-5-10)29(23,27)28/h1-7,9,15,24H,8,22H2,(H2,23,27,28)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376865
PNG
(CHEMBL412100)
Show SMILES Nc1ccc2[nH]cc(C3CC(=NN3c3ccc(cc3)S(N)(=O)=O)C(F)(F)F)c2c1
Show InChI InChI=1/C18H16F3N5O2S/c19-18(20,21)17-8-16(14-9-24-15-6-1-10(22)7-13(14)15)26(25-17)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8,22H2,(H2,23,27,28)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376866
PNG
(CHEMBL261067)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2cc(Br)ccc12)C(F)(F)F
Show InChI InChI=1/C18H14BrF3N4O2S/c19-10-1-6-13-14(9-24-15(13)7-10)16-8-17(18(20,21)22)25-26(16)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8H2,(H2,23,27,28)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376867
PNG
(CHEMBL412054)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccc(cc12)C#N)C(F)(F)F
Show InChI InChI=1/C19H14F3N5O2S/c20-19(21,22)18-8-17(15-10-25-16-6-1-11(9-23)7-14(15)16)27(26-18)12-2-4-13(5-3-12)30(24,28)29/h1-7,10,17,25H,8H2,(H2,24,28,29)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376869
PNG
(CHEMBL261255)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2cc(Cl)ccc12)C(F)(F)F
Show InChI InChI=1/C18H14ClF3N4O2S/c19-10-1-6-13-14(9-24-15(13)7-10)16-8-17(18(20,21)22)25-26(16)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8H2,(H2,23,27,28)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376855
PNG
(CHEMBL412315)
Show SMILES Nc1cccc2c(c[nH]c12)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1/C18H16F3N5O2S/c19-18(20,21)16-8-15(13-9-24-17-12(13)2-1-3-14(17)22)26(25-16)10-4-6-11(7-5-10)29(23,27)28/h1-7,9,15,24H,8,22H2,(H2,23,27,28)
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n/an/a 2.40E+3n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376856
PNG
(CHEMBL259881)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2c(cccc12)[N+]([O-])=O)C(F)(F)F
Show InChI InChI=1/C18H14F3N5O4S/c19-18(20,21)16-8-15(13-9-23-17-12(13)2-1-3-14(17)26(27)28)25(24-16)10-4-6-11(7-5-10)31(22,29)30/h1-7,9,15,23H,8H2,(H2,22,29,30)
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Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376857
PNG
(CHEMBL412286)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccc(cc12)C(O)=O)C(F)(F)F
Show InChI InChI=1/C19H15F3N4O4S/c20-19(21,22)17-8-16(14-9-24-15-6-1-10(18(27)28)7-13(14)15)26(25-17)11-2-4-12(5-3-11)31(23,29)30/h1-7,9,16,24H,8H2,(H,27,28)(H2,23,29,30)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376858
PNG
(CHEMBL265200)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccc(cc12)[N+]([O-])=O)C(F)(F)F
Show InChI InChI=1/C18H14F3N5O4S/c19-18(20,21)17-8-16(14-9-23-15-6-3-11(26(27)28)7-13(14)15)25(24-17)10-1-4-12(5-2-10)31(22,29)30/h1-7,9,16,23H,8H2,(H2,22,29,30)
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n/an/a 5.72E+4n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376859
PNG
(CHEMBL408971)
Show SMILES Nc1ccc2c(c[nH]c2c1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1/C18H16F3N5O2S/c19-18(20,21)17-8-16(14-9-24-15-7-10(22)1-6-13(14)15)26(25-17)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8,22H2,(H2,23,27,28)
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n/an/a 7.50E+3n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376860
PNG
(CHEMBL411032)
Show SMILES COc1cccc2[nH]cc(C3CC(=NN3c3ccc(cc3)S(N)(=O)=O)C(F)(F)F)c12
Show InChI InChI=1/C19H17F3N4O3S/c1-29-16-4-2-3-14-18(16)13(10-24-14)15-9-17(19(20,21)22)25-26(15)11-5-7-12(8-6-11)30(23,27)28/h2-8,10,15,24H,9H2,1H3,(H2,23,27,28)
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n/an/a 8.70E+3n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376861
PNG
(CHEMBL411719)
Show SMILES Cc1[nH]c2cc(Cl)ccc2c1C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1/C19H16ClF3N4O2S/c1-10-18(14-7-2-11(20)8-15(14)25-10)16-9-17(19(21,22)23)26-27(16)12-3-5-13(6-4-12)30(24,28)29/h2-8,16,25H,9H2,1H3,(H2,24,28,29)
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n/an/a 6.00E+3n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376862
PNG
(CHEMBL258988)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2cc(ccc12)[N+]([O-])=O)C(F)(F)F
Show InChI InChI=1/C18H14F3N5O4S/c19-18(20,21)17-8-16(14-9-23-15-7-11(26(27)28)3-6-13(14)15)25(24-17)10-1-4-12(5-2-10)31(22,29)30/h1-7,9,16,23H,8H2,(H2,22,29,30)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376863
PNG
(CHEMBL263383)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2cc(ccc12)C#N)C(F)(F)F
Show InChI InChI=1/C19H14F3N5O2S/c20-19(21,22)18-8-17(15-10-25-16-7-11(9-23)1-6-14(15)16)27(26-18)12-2-4-13(5-3-12)30(24,28)29/h1-7,10,17,25H,8H2,(H2,24,28,29)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376864
PNG
(CHEMBL263640)
Show SMILES Nc1cccc2[nH]cc(C3CC(=NN3c3ccc(cc3)S(N)(=O)=O)C(F)(F)F)c12
Show InChI InChI=1/C18H16F3N5O2S/c19-18(20,21)16-8-15(12-9-24-14-3-1-2-13(22)17(12)14)26(25-16)10-4-6-11(7-5-10)29(23,27)28/h1-7,9,15,24H,8,22H2,(H2,23,27,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376865
PNG
(CHEMBL412100)
Show SMILES Nc1ccc2[nH]cc(C3CC(=NN3c3ccc(cc3)S(N)(=O)=O)C(F)(F)F)c2c1
Show InChI InChI=1/C18H16F3N5O2S/c19-18(20,21)17-8-16(14-9-24-15-6-1-10(22)7-13(14)15)26(25-17)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8,22H2,(H2,23,27,28)
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n/an/a 850n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376866
PNG
(CHEMBL261067)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2cc(Br)ccc12)C(F)(F)F
Show InChI InChI=1/C18H14BrF3N4O2S/c19-10-1-6-13-14(9-24-15(13)7-10)16-8-17(18(20,21)22)25-26(16)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8H2,(H2,23,27,28)
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n/an/a 4.40E+3n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376867
PNG
(CHEMBL412054)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccc(cc12)C#N)C(F)(F)F
Show InChI InChI=1/C19H14F3N5O2S/c20-19(21,22)18-8-17(15-10-25-16-6-1-11(9-23)7-14(15)16)27(26-18)12-2-4-13(5-3-12)30(24,28)29/h1-7,10,17,25H,8H2,(H2,24,28,29)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376869
PNG
(CHEMBL261255)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2cc(Cl)ccc12)C(F)(F)F
Show InChI InChI=1/C18H14ClF3N4O2S/c19-10-1-6-13-14(9-24-15(13)7-10)16-8-17(18(20,21)22)25-26(16)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8H2,(H2,23,27,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376853
PNG
(CHEMBL258986)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F
Show InChI InChI=1/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50376853
PNG
(CHEMBL258986)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F
Show InChI InChI=1/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376853
PNG
(CHEMBL258986)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F
Show InChI InChI=1/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27)
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n/an/a 850n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50376853
PNG
(CHEMBL258986)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F
Show InChI InChI=1/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Temple University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 by enzyme immuno assay


Bioorg Med Chem 16: 3907-16 (2008)


Article DOI: 10.1016/j.bmc.2008.01.047
BindingDB Entry DOI: 10.7270/Q2S46SV4
More data for this
Ligand-Target Pair