Compounds in cluster

18 similar compounds to monomer 50380709

Wt: 388.4 BDBM50380683	Wt: 492.5 BDBM50380684	Wt: 406.4 BDBM50380690	Wt: 406.4 BDBM50380692	Wt: 406.4 BDBM50380693
Wt: 422.9 BDBM50380694	Wt: 402.4 BDBM50380696	Wt: 456.4 BDBM50380697	Wt: 456.4 BDBM50380699	Wt: 424.4 BDBM50380701
Wt: 424.4 BDBM50380702	Wt: 457.3 BDBM50380703	Wt: 474.4 BDBM50380705	Wt: 450.4 BDBM50380707	Wt: 464.5 BDBM50380708

Displayed 1 to 15 (of 18 total ) | Next | Last >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50380683,50380684,50380690,50380692,50380693,50380694,50380696,50380697,50380699,50380701,50380702,50380703,50380705,50380707,50380708
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380683 (CHEMBL2017507) Show SMILES CCOP(=O)(OCC)C(Cc1ccccc1)c1sc2ccccc2c1C Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380708 (CHEMBL2017664) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380690 (CHEMBL2017505) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380692 (CHEMBL2017508) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380693 (CHEMBL2017509) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380694 (CHEMBL2017510) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380696 (CHEMBL2017512) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380697 (CHEMBL2017513) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380699 (CHEMBL2017655) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	365	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380701 (CHEMBL2017657) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380702 (CHEMBL2017658) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380703 (CHEMBL2017659) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380705 (CHEMBL2017661) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380707 (CHEMBL2017663) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380684 (CHEMBL2017666) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
Janssen Pharmaceutica NV Curated by ChEMBL					More data for this Ligand-Target Pair