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1 similar compounds to monomer 50380714

Compile data set for download or QSAR
Wt: 420.4
BDBM50380712

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380712   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential M8 protein


(Canis lupus familiaris (Dog))
BDBM50380712
PNG
(CHEMBL2017670)
Show SMILES CCCP(=O)(CCC)C(Cc1ccc(F)c(F)c1)c1sc2ccccc2c1C
Show InChI InChI=1S/C23H27F2OPS/c1-4-12-27(26,13-5-2)21(15-17-10-11-19(24)20(25)14-17)23-16(3)18-8-6-7-9-22(18)28-23/h6-11,14,21H,4-5,12-13,15H2,1-3H3
KEGG

UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 165n/an/an/an/an/an/a



Janssen Pharmaceutica NV

Curated by ChEMBL


Assay Description
Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...


Bioorg Med Chem Lett 22: 2922-6 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.060
BindingDB Entry DOI: 10.7270/Q2TM7C48
More data for this
Ligand-Target Pair