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1 similar compounds to monomer 50382392

Compile data set for download or QSAR
Wt: 325.1
BDBM50382397

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50382397   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50382397
PNG
(CHEMBL2022164)
Show SMILES CN1CCC(=O)N=C1NC(=O)Nc1cccc(Br)c1
Show InChI InChI=1S/C12H13BrN4O2/c1-17-6-5-10(18)15-11(17)16-12(19)14-9-4-2-3-8(13)7-9/h2-4,7H,5-6H2,1H3,(H2,14,15,16,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 96n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonist activity at human mGluR5 expressed in CHO-K1 cells assessed as inhibition of glutamate-induced intracellular calcium mobilization


ACS Med Chem Lett 2: 882-884 (2011)


Article DOI: 10.1021/ml200162f
BindingDB Entry DOI: 10.7270/Q2XW4KT8
More data for this
Ligand-Target Pair