BindingDB logo
myBDB logout

2 similar compounds to monomer 50387888

Compile data set for download or QSAR
Wt: 400.5
BDBM50387898
Wt: 372.5
BDBM50387902

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50387898,50387902   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))
BDBM50387898
PNG
(CHEMBL2058399)
Show SMILES CC(C)(C)OC(=O)N1CCC(CCCNc2ccc3c(CCCCC3=O)c2)CC1
Show InChI InChI=1S/C24H36N2O3/c1-24(2,3)29-23(28)26-15-12-18(13-16-26)7-6-14-25-20-10-11-21-19(17-20)8-4-5-9-22(21)27/h10-11,17-18,25H,4-9,12-16H2,1-3H3
Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 770n/an/an/an/a



Sanwa Kagaku Kenkyusho Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assay


Bioorg Med Chem Lett 22: 5123-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.05.117
BindingDB Entry DOI: 10.7270/Q2TD9ZC4
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Mus musculus)
BDBM50387902
PNG
(CHEMBL2058403)
Show SMILES CC(C)(C)OC(=O)N1CCC(CCCNc2ccc3CCC(=O)c3c2)CC1
Show InChI InChI=1S/C22H32N2O3/c1-22(2,3)27-21(26)24-13-10-16(11-14-24)5-4-12-23-18-8-6-17-7-9-20(25)19(17)15-18/h6,8,15-16,23H,4-5,7,9-14H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 123n/an/an/an/a



Sanwa Kagaku Kenkyusho Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assay


Bioorg Med Chem Lett 22: 5123-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.05.117
BindingDB Entry DOI: 10.7270/Q2TD9ZC4
More data for this
Ligand-Target Pair
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))
BDBM50387902
PNG
(CHEMBL2058403)
Show SMILES CC(C)(C)OC(=O)N1CCC(CCCNc2ccc3CCC(=O)c3c2)CC1
Show InChI InChI=1S/C22H32N2O3/c1-22(2,3)27-21(26)24-13-10-16(11-14-24)5-4-12-23-18-8-6-17-7-9-20(25)19(17)15-18/h6,8,15-16,23H,4-5,7,9-14H2,1-3H3
Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 46n/an/an/an/a



Sanwa Kagaku Kenkyusho Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assay


Bioorg Med Chem Lett 22: 5123-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.05.117
BindingDB Entry DOI: 10.7270/Q2TD9ZC4
More data for this
Ligand-Target Pair