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1 similar compounds to monomer 50387903

Compile data set for download or QSAR
Wt: 374.4
BDBM50387899

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50387899   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucose-dependent insulinotropic receptor


(Mus musculus)
BDBM50387899
PNG
(CHEMBL2058400)
Show SMILES CC(C)(C)OC(=O)N1CCC(CCCNc2ccc3c(O)coc3c2)CC1
Show InChI InChI=1S/C21H30N2O4/c1-21(2,3)27-20(25)23-11-8-15(9-12-23)5-4-10-22-16-6-7-17-18(24)14-26-19(17)13-16/h6-7,13-15,22,24H,4-5,8-12H2,1-3H3
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 66n/an/an/an/a



Sanwa Kagaku Kenkyusho Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assay


Bioorg Med Chem Lett 22: 5123-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.05.117
BindingDB Entry DOI: 10.7270/Q2TD9ZC4
More data for this
Ligand-Target Pair
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))
BDBM50387899
PNG
(CHEMBL2058400)
Show SMILES CC(C)(C)OC(=O)N1CCC(CCCNc2ccc3c(O)coc3c2)CC1
Show InChI InChI=1S/C21H30N2O4/c1-21(2,3)27-20(25)23-11-8-15(9-12-23)5-4-10-22-16-6-7-17-18(24)14-26-19(17)13-16/h6-7,13-15,22,24H,4-5,8-12H2,1-3H3
Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 52n/an/an/an/a



Sanwa Kagaku Kenkyusho Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assay


Bioorg Med Chem Lett 22: 5123-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.05.117
BindingDB Entry DOI: 10.7270/Q2TD9ZC4
More data for this
Ligand-Target Pair