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6 similar compounds to monomer 50406165

Compile data set for download or QSAR
Wt: 408.9
BDBM50406155
Wt: 392.4
BDBM50406162
Wt: 419.4
BDBM50406138
Wt: 241.3
BDBM50406141
Wt: 227.3
BDBM50406149
Wt: 402.5
BDBM50406153

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50406155,50406162,50406138,50406141,50406149,50406153   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406138
PNG
(CHEMBL100170)
Show SMILES [O-][N+](=O)c1ccccc1NC(=O)CCN1CCN2Cc3[nH]c4ccccc4c3CC2C1
Show InChI InChI=1S/C23H25N5O3/c29-23(25-20-7-3-4-8-22(20)28(30)31)9-10-26-11-12-27-15-21-18(13-16(27)14-26)17-5-1-2-6-19(17)24-21/h1-8,16,24H,9-15H2,(H,25,29)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.74E+3n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum


J Med Chem 33: 2970-6 (1990)


Article DOI: 10.1021/jm00173a011
BindingDB Entry DOI: 10.7270/Q2Z89DMH
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406141
PNG
(CHEMBL321104)
Show SMILES CN1CCN2Cc3[nH]c4ccccc4c3CC2C1
Show InChI InChI=1S/C15H19N3/c1-17-6-7-18-10-15-13(8-11(18)9-17)12-4-2-3-5-14(12)16-15/h2-5,11,16H,6-10H2,1H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 283n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum


J Med Chem 33: 2970-6 (1990)


Article DOI: 10.1021/jm00173a011
BindingDB Entry DOI: 10.7270/Q2Z89DMH
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406162
PNG
(CHEMBL101029)
Show SMILES Fc1ccccc1NC(=O)CCN1CCN2Cc3[nH]c4ccccc4c3CC2C1
Show InChI InChI=1S/C23H25FN4O/c24-19-6-2-4-8-21(19)26-23(29)9-10-27-11-12-28-15-22-18(13-16(28)14-27)17-5-1-3-7-20(17)25-22/h1-8,16,25H,9-15H2,(H,26,29)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.28E+3n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum


J Med Chem 33: 2970-6 (1990)


Article DOI: 10.1021/jm00173a011
BindingDB Entry DOI: 10.7270/Q2Z89DMH
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406153
PNG
(CHEMBL101625)
Show SMILES CCc1ccccc1NC(=O)CCN1CCN2Cc3[nH]c4ccccc4c3CC2C1
Show InChI InChI=1S/C25H30N4O/c1-2-18-7-3-5-9-22(18)27-25(30)11-12-28-13-14-29-17-24-21(15-19(29)16-28)20-8-4-6-10-23(20)26-24/h3-10,19,26H,2,11-17H2,1H3,(H,27,30)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 634n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum


J Med Chem 33: 2970-6 (1990)


Article DOI: 10.1021/jm00173a011
BindingDB Entry DOI: 10.7270/Q2Z89DMH
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406155
PNG
(CHEMBL101217)
Show SMILES Clc1ccccc1NC(=O)CCN1CCN2Cc3[nH]c4ccccc4c3CC2C1
Show InChI InChI=1S/C23H25ClN4O/c24-19-6-2-4-8-21(19)26-23(29)9-10-27-11-12-28-15-22-18(13-16(28)14-27)17-5-1-3-7-20(17)25-22/h1-8,16,25H,9-15H2,(H,26,29)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 979n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum


J Med Chem 33: 2970-6 (1990)


Article DOI: 10.1021/jm00173a011
BindingDB Entry DOI: 10.7270/Q2Z89DMH
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406149
PNG
(CHEMBL101491)
Show SMILES C1CN2Cc3[nH]c4ccccc4c3CC2CN1
Show InChI InChI=1S/C14H17N3/c1-2-4-13-11(3-1)12-7-10-8-15-5-6-17(10)9-14(12)16-13/h1-4,10,15-16H,5-9H2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 535n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum


J Med Chem 33: 2970-6 (1990)


Article DOI: 10.1021/jm00173a011
BindingDB Entry DOI: 10.7270/Q2Z89DMH
More data for this
Ligand-Target Pair