BindingDB logo
myBDB logout

2 similar compounds to monomer 50406144

Compile data set for download or QSAR
Wt: 363.4
BDBM50406164
Wt: 369.8
BDBM50406148

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50406164,50406148   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406164
PNG
(CHEMBL421393)
Show SMILES CCc1ccccc1NC(=O)CCN1CCN2Cc3ccccc3CC2C1
Show InChI InChI=1S/C23H29N3O/c1-2-18-7-5-6-10-22(18)24-23(27)11-12-25-13-14-26-16-20-9-4-3-8-19(20)15-21(26)17-25/h3-10,21H,2,11-17H2,1H3,(H,24,27)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 525n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum


J Med Chem 33: 2970-6 (1990)


Article DOI: 10.1021/jm00173a011
BindingDB Entry DOI: 10.7270/Q2Z89DMH
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406148
PNG
(CHEMBL319817)
Show SMILES Clc1ccccc1NC(=O)CCN1CCN2Cc3ccccc3CC2C1
Show InChI InChI=1S/C21H24ClN3O/c22-19-7-3-4-8-20(19)23-21(26)9-10-24-11-12-25-14-17-6-2-1-5-16(17)13-18(25)15-24/h1-8,18H,9-15H2,(H,23,26)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 677n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum


J Med Chem 33: 2970-6 (1990)


Article DOI: 10.1021/jm00173a011
BindingDB Entry DOI: 10.7270/Q2Z89DMH
More data for this
Ligand-Target Pair