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1 similar compounds to monomer 50406783

Compile data set for download or QSAR
Wt: 242.2
BDBM50406766

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50406766   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM50406766
PNG
(CHEMBL36497)
Show SMILES Cc1noc(n1)-c1ccc2[nH]cc(CCN)c2c1
Show InChI InChI=1S/C13H14N4O/c1-8-16-13(18-17-8)9-2-3-12-11(6-9)10(4-5-14)7-15-12/h2-3,6-7,15H,4-5,14H2,1H3
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Article
PubMed
n/an/a 1.26E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from pig cortex 5-hydroxytryptamine 1C receptor


J Med Chem 36: 1529-38 (1993)


Article DOI: 10.1021/jm00063a003
BindingDB Entry DOI: 10.7270/Q22V2HB9
More data for this
Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor


(Sus scrofa)
BDBM50406766
PNG
(CHEMBL36497)
Show SMILES Cc1noc(n1)-c1ccc2[nH]cc(CCN)c2c1
Show InChI InChI=1S/C13H14N4O/c1-8-16-13(18-17-8)9-2-3-12-11(6-9)10(4-5-14)7-15-12/h2-3,6-7,15H,4-5,14H2,1H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane


J Med Chem 36: 1529-38 (1993)


Article DOI: 10.1021/jm00063a003
BindingDB Entry DOI: 10.7270/Q22V2HB9
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50406766
PNG
(CHEMBL36497)
Show SMILES Cc1noc(n1)-c1ccc2[nH]cc(CCN)c2c1
Show InChI InChI=1S/C13H14N4O/c1-8-16-13(18-17-8)9-2-3-12-11(6-9)10(4-5-14)7-15-12/h2-3,6-7,15H,4-5,14H2,1H3
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Article
PubMed
n/an/a 1.59E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
isplacement of [3H]DOB from rat cortex homogenate 5-hydroxytryptamine 2 receptor


J Med Chem 36: 1529-38 (1993)


Article DOI: 10.1021/jm00063a003
BindingDB Entry DOI: 10.7270/Q22V2HB9
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50406766
PNG
(CHEMBL36497)
Show SMILES Cc1noc(n1)-c1ccc2[nH]cc(CCN)c2c1
Show InChI InChI=1S/C13H14N4O/c1-8-16-13(18-17-8)9-2-3-12-11(6-9)10(4-5-14)7-15-12/h2-3,6-7,15H,4-5,14H2,1H3
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Article
PubMed
n/an/a<1.00E+4n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 from rat cortex homogenate 5-hydroxytryptamine 3 receptor


J Med Chem 36: 1529-38 (1993)


Article DOI: 10.1021/jm00063a003
BindingDB Entry DOI: 10.7270/Q22V2HB9
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50406766
PNG
(CHEMBL36497)
Show SMILES Cc1noc(n1)-c1ccc2[nH]cc(CCN)c2c1
Show InChI InChI=1S/C13H14N4O/c1-8-16-13(18-17-8)9-2-3-12-11(6-9)10(4-5-14)7-15-12/h2-3,6-7,15H,4-5,14H2,1H3
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Article
PubMed
n/an/a 63n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from pig cortex 5-hydroxytryptamine 1A receptor


J Med Chem 36: 1529-38 (1993)


Article DOI: 10.1021/jm00063a003
BindingDB Entry DOI: 10.7270/Q22V2HB9
More data for this
Ligand-Target Pair