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7 similar compounds to monomer 50431430

Compile data set for download or QSAR
Wt: 312.4
BDBM50431424
Wt: 348.4
BDBM50431425
Wt: 348.4
BDBM50431426
Wt: 312.4
BDBM50431427
Wt: 312.4
BDBM50431428
Wt: 332.8
BDBM50431429
Wt: 298.3
BDBM50431431

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50431424,50431425,50431426,50431427,50431428,50431429,50431431   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431426
PNG
(CHEMBL2348280)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2cccc3ccccc23)c1=O
Show InChI InChI=1S/C22H24N2O2/c1-4-5-13-24-16(3)15(2)14-20(22(24)26)23-21(25)19-12-8-10-17-9-6-7-11-18(17)19/h6-12,14H,4-5,13H2,1-3H3,(H,23,25)
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12n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB2 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431424
PNG
(CHEMBL2348277)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2ccccc2C)c1=O
Show InChI InChI=1S/C19H24N2O2/c1-5-6-11-21-15(4)14(3)12-17(19(21)23)20-18(22)16-10-8-7-9-13(16)2/h7-10,12H,5-6,11H2,1-4H3,(H,20,22)
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14n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB2 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431429
PNG
(CHEMBL2348276)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2ccccc2Cl)c1=O
Show InChI InChI=1S/C18H21ClN2O2/c1-4-5-10-21-13(3)12(2)11-16(18(21)23)20-17(22)14-8-6-7-9-15(14)19/h6-9,11H,4-5,10H2,1-3H3,(H,20,22)
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16n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB2 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431426
PNG
(CHEMBL2348280)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2cccc3ccccc23)c1=O
Show InChI InChI=1S/C22H24N2O2/c1-4-5-13-24-16(3)15(2)14-20(22(24)26)23-21(25)19-12-8-10-17-9-6-7-11-18(17)19/h6-12,14H,4-5,13H2,1-3H3,(H,23,25)
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19n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB1 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431428
PNG
(CHEMBL2348278)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2cccc(C)c2)c1=O
Show InChI InChI=1S/C19H24N2O2/c1-5-6-10-21-15(4)14(3)12-17(19(21)23)20-18(22)16-9-7-8-13(2)11-16/h7-9,11-12H,5-6,10H2,1-4H3,(H,20,22)
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42n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB2 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431427
PNG
(CHEMBL2348279)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2ccc(C)cc2)c1=O
Show InChI InChI=1S/C19H24N2O2/c1-5-6-11-21-15(4)14(3)12-17(19(21)23)20-18(22)16-9-7-13(2)8-10-16/h7-10,12H,5-6,11H2,1-4H3,(H,20,22)
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72n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB2 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431431
PNG
(CHEMBL2348274)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2ccccc2)c1=O
Show InChI InChI=1S/C18H22N2O2/c1-4-5-11-20-14(3)13(2)12-16(18(20)22)19-17(21)15-9-7-6-8-10-15/h6-10,12H,4-5,11H2,1-3H3,(H,19,21)
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89n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB2 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431428
PNG
(CHEMBL2348278)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2cccc(C)c2)c1=O
Show InChI InChI=1S/C19H24N2O2/c1-5-6-10-21-15(4)14(3)12-17(19(21)23)20-18(22)16-9-7-8-13(2)11-16/h7-9,11-12H,5-6,10H2,1-4H3,(H,20,22)
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343n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB1 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431424
PNG
(CHEMBL2348277)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2ccccc2C)c1=O
Show InChI InChI=1S/C19H24N2O2/c1-5-6-11-21-15(4)14(3)12-17(19(21)23)20-18(22)16-10-8-7-9-13(16)2/h7-10,12H,5-6,11H2,1-4H3,(H,20,22)
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390n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB1 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431429
PNG
(CHEMBL2348276)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2ccccc2Cl)c1=O
Show InChI InChI=1S/C18H21ClN2O2/c1-4-5-10-21-13(3)12(2)11-16(18(21)23)20-17(22)14-8-6-7-9-15(14)19/h6-9,11H,4-5,10H2,1-3H3,(H,20,22)
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391n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB1 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431425
PNG
(CHEMBL2348281)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2ccc3ccccc3c2)c1=O
Show InChI InChI=1S/C22H24N2O2/c1-4-5-12-24-16(3)15(2)13-20(22(24)26)23-21(25)19-11-10-17-8-6-7-9-18(17)14-19/h6-11,13-14H,4-5,12H2,1-3H3,(H,23,25)
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768n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB2 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431427
PNG
(CHEMBL2348279)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2ccc(C)cc2)c1=O
Show InChI InChI=1S/C19H24N2O2/c1-5-6-11-21-15(4)14(3)12-17(19(21)23)20-18(22)16-9-7-13(2)8-10-16/h7-10,12H,5-6,11H2,1-4H3,(H,20,22)
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854n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB1 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431431
PNG
(CHEMBL2348274)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2ccccc2)c1=O
Show InChI InChI=1S/C18H22N2O2/c1-4-5-11-20-14(3)13(2)12-16(18(20)22)19-17(21)15-9-7-6-8-10-15/h6-10,12H,4-5,11H2,1-3H3,(H,19,21)
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1.38E+3n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB1 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431425
PNG
(CHEMBL2348281)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2ccc3ccccc3c2)c1=O
Show InChI InChI=1S/C22H24N2O2/c1-4-5-12-24-16(3)15(2)13-20(22(24)26)23-21(25)19-11-10-17-8-6-7-9-18(17)14-19/h6-11,13-14H,4-5,12H2,1-3H3,(H,23,25)
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>5.00E+3n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [H3]-CP-55940 from human recombinant CB1 receptor expressed in CHO cells


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50431424
PNG
(CHEMBL2348277)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)c2ccccc2C)c1=O
Show InChI InChI=1S/C19H24N2O2/c1-5-6-11-21-15(4)14(3)12-17(19(21)23)20-18(22)16-10-8-7-9-13(16)2/h7-10,12H,5-6,11H2,1-4H3,(H,20,22)
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n/an/a 13n/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced accumulation of cAMP


Bioorg Med Chem 21: 2045-55 (2013)


Article DOI: 10.1016/j.bmc.2013.01.006
BindingDB Entry DOI: 10.7270/Q2PG1T2V
More data for this
Ligand-Target Pair