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1 similar compounds to monomer 50432765

Compile data set for download or QSAR
Wt: 408.4
BDBM50432764

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50432764   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50432764
PNG
(CHEMBL2348795)
Show SMILES C[C@H](Nc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1
Show InChI InChI=1S/C25H20N4O2/c1-16(27-21-8-4-6-17-5-2-3-7-20(17)21)24(30)28-19-9-10-23-22(15-19)29-25(31-23)18-11-13-26-14-12-18/h2-16,27H,1H3,(H,28,30)/t16-/m0/s1
PDB
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of human IMPDH2


J Med Chem 56: 4028-43 (2013)


Article DOI: 10.1021/jm400241j
BindingDB Entry DOI: 10.7270/Q2GF0VWF
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50432764
PNG
(CHEMBL2348795)
Show SMILES C[C@H](Nc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1
Show InChI InChI=1S/C25H20N4O2/c1-16(27-21-8-4-6-17-5-2-3-7-20(17)21)24(30)28-19-9-10-23-22(15-19)29-25(31-23)18-11-13-26-14-12-18/h2-16,27H,1H3,(H,28,30)/t16-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...


J Med Chem 56: 4028-43 (2013)


Article DOI: 10.1021/jm400241j
BindingDB Entry DOI: 10.7270/Q2GF0VWF
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50432764
PNG
(CHEMBL2348795)
Show SMILES C[C@H](Nc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1
Show InChI InChI=1S/C25H20N4O2/c1-16(27-21-8-4-6-17-5-2-3-7-20(17)21)24(30)28-19-9-10-23-22(15-19)29-25(31-23)18-11-13-26-14-12-18/h2-16,27H,1H3,(H,28,30)/t16-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...


J Med Chem 56: 4028-43 (2013)


Article DOI: 10.1021/jm400241j
BindingDB Entry DOI: 10.7270/Q2GF0VWF
More data for this
Ligand-Target Pair