BindingDB logo
myBDB logout

6 similar compounds to monomer 50433055

Compile data set for download or QSAR
Wt: 278.2
BDBM50433068
Wt: 310.2
BDBM50433054
Wt: 296.2
BDBM50433057
Wt: 312.7
BDBM50433058
Wt: 292.2
BDBM50433067
Wt: 298.6
BDBM50433060

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50433068,50433054,50433057,50433058,50433067,50433060   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase N


(Homo sapiens (Human))
BDBM50433054
PNG
(CHEMBL2376114)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCCO2)c2cc(F)ccc12
Show InChI InChI=1S/C14H15FN2O5/c15-9-3-4-11-10(7-9)14(21-5-1-2-6-22-14)13(19)17(11)8-12(18)16-20/h3-4,7,20H,1-2,5-6,8H2,(H,16,18)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.52E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50433057
PNG
(CHEMBL2376109)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCO2)c2cc(F)ccc12
Show InChI InChI=1S/C13H13FN2O5/c14-8-2-3-10-9(6-8)13(20-4-1-5-21-13)12(18)16(10)7-11(17)15-19/h2-3,6,19H,1,4-5,7H2,(H,15,17)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.75E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50433058
PNG
(CHEMBL2376108)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCO2)c2cc(Cl)ccc12
Show InChI InChI=1S/C13H13ClN2O5/c14-8-2-3-10-9(6-8)13(20-4-1-5-21-13)12(18)16(10)7-11(17)15-19/h2-3,6,19H,1,4-5,7H2,(H,15,17)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.09E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50433060
PNG
(CHEMBL2376104)
Show SMILES ONC(=O)CN1C(=O)C2(OCCO2)c2cc(Cl)ccc12
Show InChI InChI=1S/C12H11ClN2O5/c13-7-1-2-9-8(5-7)12(19-3-4-20-12)11(17)15(9)6-10(16)14-18/h1-2,5,18H,3-4,6H2,(H,14,16)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.58E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433060
PNG
(CHEMBL2376104)
Show SMILES ONC(=O)CN1C(=O)C2(OCCO2)c2cc(Cl)ccc12
Show InChI InChI=1S/C12H11ClN2O5/c13-7-1-2-9-8(5-7)12(19-3-4-20-12)11(17)15(9)6-10(16)14-18/h1-2,5,18H,3-4,6H2,(H,14,16)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 310n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433067
PNG
(CHEMBL2376112)
Show SMILES Cc1ccc2N(CC(=O)NO)C(=O)C3(OCCCO3)c2c1
Show InChI InChI=1S/C14H16N2O5/c1-9-3-4-11-10(7-9)14(20-5-2-6-21-14)13(18)16(11)8-12(17)15-19/h3-4,7,19H,2,5-6,8H2,1H3,(H,15,17)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.33E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433068
PNG
(CHEMBL2376111)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCO2)c2ccccc12
Show InChI InChI=1S/C13H14N2O5/c16-11(14-18)8-15-10-5-2-1-4-9(10)13(12(15)17)19-6-3-7-20-13/h1-2,4-5,18H,3,6-8H2,(H,14,16)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.66E+5n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433057
PNG
(CHEMBL2376109)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCO2)c2cc(F)ccc12
Show InChI InChI=1S/C13H13FN2O5/c14-8-2-3-10-9(6-8)13(20-4-1-5-21-13)12(18)16(10)7-11(17)15-19/h2-3,6,19H,1,4-5,7H2,(H,15,17)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.71E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433058
PNG
(CHEMBL2376108)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCO2)c2cc(Cl)ccc12
Show InChI InChI=1S/C13H13ClN2O5/c14-8-2-3-10-9(6-8)13(20-4-1-5-21-13)12(18)16(10)7-11(17)15-19/h2-3,6,19H,1,4-5,7H2,(H,15,17)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433054
PNG
(CHEMBL2376114)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCCO2)c2cc(F)ccc12
Show InChI InChI=1S/C14H15FN2O5/c15-9-3-4-11-10(7-9)14(21-5-1-2-6-22-14)13(19)17(11)8-12(18)16-20/h3-4,7,20H,1-2,5-6,8H2,(H,16,18)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.06E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair