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4 similar compounds to monomer 50438501

Compile data set for download or QSAR
Wt: 439.4
BDBM50438500
Wt: 381.3
BDBM50438502
Wt: 339.3
BDBM50438503
Wt: 323.3
BDBM50438504

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50438500,50438502,50438503,50438504   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acidic alpha-glucosidase


(Rattus norvegicus)
BDBM50438500
PNG
(CHEMBL2414822)
Show SMILES CC(=O)Oc1ccc(\C=C\C(=O)NC[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1OC(C)=O
Show InChI InChI=1S/C20H25NO10/c1-10(23)29-13-5-3-12(7-14(13)30-11(2)24)4-6-17(25)21-8-15-18(26)20(28)19(27)16(9-22)31-15/h3-7,15-16,18-20,22,26-28H,8-9H2,1-2H3,(H,21,25)/b6-4+/t15-,16+,18-,19+,20+/m0/s1
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4.80E+3n/an/an/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Competitive inhibition of rat intestinal maltase using maltose as substrate by Lineweaver-Burk plot analysis


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Rattus norvegicus (Rat))
BDBM50438500
PNG
(CHEMBL2414822)
Show SMILES CC(=O)Oc1ccc(\C=C\C(=O)NC[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1OC(C)=O
Show InChI InChI=1S/C20H25NO10/c1-10(23)29-13-5-3-12(7-14(13)30-11(2)24)4-6-17(25)21-8-15-18(26)20(28)19(27)16(9-22)31-15/h3-7,15-16,18-20,22,26-28H,8-9H2,1-2H3,(H,21,25)/b6-4+/t15-,16+,18-,19+,20+/m0/s1
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1.71E+4n/an/an/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Competitive inhibition of rat intestinal sucrase using sucrose as substrate by Lineweaver-Burk plot analysis


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
Acidic alpha-glucosidase


(Rattus norvegicus)
BDBM50438503
PNG
(CHEMBL2414819)
Show SMILES OC[C@H]1O[C@@H](CNC(=O)\C=C\c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C16H21NO7/c18-8-12-15(22)16(23)14(21)11(24-12)7-17-13(20)6-3-9-1-4-10(19)5-2-9/h1-6,11-12,14-16,18-19,21-23H,7-8H2,(H,17,20)/b6-3+/t11-,12+,14-,15+,16+/m0/s1
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n/an/a 3.69E+5n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal maltase using maltose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
Acidic alpha-glucosidase


(Rattus norvegicus)
BDBM50438504
PNG
(CHEMBL2414818)
Show SMILES OC[C@H]1O[C@@H](CNC(=O)\C=C\c2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C16H21NO6/c18-9-12-15(21)16(22)14(20)11(23-12)8-17-13(19)7-6-10-4-2-1-3-5-10/h1-7,11-12,14-16,18,20-22H,8-9H2,(H,17,19)/b7-6+/t11-,12+,14-,15+,16+/m0/s1
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n/an/a 1.68E+5n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal maltase using maltose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM50438500
PNG
(CHEMBL2414822)
Show SMILES CC(=O)Oc1ccc(\C=C\C(=O)NC[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1OC(C)=O
Show InChI InChI=1S/C20H25NO10/c1-10(23)29-13-5-3-12(7-14(13)30-11(2)24)4-6-17(25)21-8-15-18(26)20(28)19(27)16(9-22)31-15/h3-7,15-16,18-20,22,26-28H,8-9H2,1-2H3,(H,21,25)/b6-4+/t15-,16+,18-,19+,20+/m0/s1
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n/an/a 3.55E+5n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as 4-nitrophenol release from 4-nitrophenyl alpha-D-glucopyranoside preincubated fo...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM50438502
PNG
(CHEMBL2414820)
Show SMILES CC(=O)Oc1ccc(\C=C\C(=O)NC[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1
Show InChI InChI=1S/C18H23NO8/c1-10(21)26-12-5-2-11(3-6-12)4-7-15(22)19-8-13-16(23)18(25)17(24)14(9-20)27-13/h2-7,13-14,16-18,20,23-25H,8-9H2,1H3,(H,19,22)/b7-4+/t13-,14+,16-,17+,18+/m0/s1
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n/an/a 1.42E+5n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as 4-nitrophenol release from 4-nitrophenyl alpha-D-glucopyranoside preincubated fo...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Rattus norvegicus (Rat))
BDBM50438504
PNG
(CHEMBL2414818)
Show SMILES OC[C@H]1O[C@@H](CNC(=O)\C=C\c2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C16H21NO6/c18-9-12-15(21)16(22)14(20)11(23-12)8-17-13(19)7-6-10-4-2-1-3-5-10/h1-7,11-12,14-16,18,20-22H,8-9H2,(H,17,19)/b7-6+/t11-,12+,14-,15+,16+/m0/s1
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n/an/a 3.14E+5n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM50438504
PNG
(CHEMBL2414818)
Show SMILES OC[C@H]1O[C@@H](CNC(=O)\C=C\c2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C16H21NO6/c18-9-12-15(21)16(22)14(20)11(23-12)8-17-13(19)7-6-10-4-2-1-3-5-10/h1-7,11-12,14-16,18,20-22H,8-9H2,(H,17,19)/b7-6+/t11-,12+,14-,15+,16+/m0/s1
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n/an/a 2.30E+3n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as 4-nitrophenol release from 4-nitrophenyl alpha-D-glucopyranoside preincubated fo...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Rattus norvegicus (Rat))
BDBM50438500
PNG
(CHEMBL2414822)
Show SMILES CC(=O)Oc1ccc(\C=C\C(=O)NC[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1OC(C)=O
Show InChI InChI=1S/C20H25NO10/c1-10(23)29-13-5-3-12(7-14(13)30-11(2)24)4-6-17(25)21-8-15-18(26)20(28)19(27)16(9-22)31-15/h3-7,15-16,18-20,22,26-28H,8-9H2,1-2H3,(H,21,25)/b6-4+/t15-,16+,18-,19+,20+/m0/s1
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n/an/a 1.04E+4n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Rattus norvegicus (Rat))
BDBM50438502
PNG
(CHEMBL2414820)
Show SMILES CC(=O)Oc1ccc(\C=C\C(=O)NC[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1
Show InChI InChI=1S/C18H23NO8/c1-10(21)26-12-5-2-11(3-6-12)4-7-15(22)19-8-13-16(23)18(25)17(24)14(9-20)27-13/h2-7,13-14,16-18,20,23-25H,8-9H2,1H3,(H,19,22)/b7-4+/t13-,14+,16-,17+,18+/m0/s1
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n/an/a 1.55E+5n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Rattus norvegicus (Rat))
BDBM50438503
PNG
(CHEMBL2414819)
Show SMILES OC[C@H]1O[C@@H](CNC(=O)\C=C\c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C16H21NO7/c18-8-12-15(22)16(23)14(21)11(24-12)7-17-13(20)6-3-9-1-4-10(19)5-2-9/h1-6,11-12,14-16,18-19,21-23H,7-8H2,(H,17,20)/b6-3+/t11-,12+,14-,15+,16+/m0/s1
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n/an/a 4.06E+5n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
Acidic alpha-glucosidase


(Rattus norvegicus)
BDBM50438502
PNG
(CHEMBL2414820)
Show SMILES CC(=O)Oc1ccc(\C=C\C(=O)NC[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1
Show InChI InChI=1S/C18H23NO8/c1-10(21)26-12-5-2-11(3-6-12)4-7-15(22)19-8-13-16(23)18(25)17(24)14(9-20)27-13/h2-7,13-14,16-18,20,23-25H,8-9H2,1H3,(H,19,22)/b7-4+/t13-,14+,16-,17+,18+/m0/s1
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n/an/a 1.66E+5n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal maltase using maltose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
Acidic alpha-glucosidase


(Rattus norvegicus)
BDBM50438500
PNG
(CHEMBL2414822)
Show SMILES CC(=O)Oc1ccc(\C=C\C(=O)NC[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1OC(C)=O
Show InChI InChI=1S/C20H25NO10/c1-10(23)29-13-5-3-12(7-14(13)30-11(2)24)4-6-17(25)21-8-15-18(26)20(28)19(27)16(9-22)31-15/h3-7,15-16,18-20,22,26-28H,8-9H2,1-2H3,(H,21,25)/b6-4+/t15-,16+,18-,19+,20+/m0/s1
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n/an/a 5.10E+3n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal maltase using maltose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM50438503
PNG
(CHEMBL2414819)
Show SMILES OC[C@H]1O[C@@H](CNC(=O)\C=C\c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C16H21NO7/c18-8-12-15(22)16(23)14(21)11(24-12)7-17-13(20)6-3-9-1-4-10(19)5-2-9/h1-6,11-12,14-16,18-19,21-23H,7-8H2,(H,17,20)/b6-3+/t11-,12+,14-,15+,16+/m0/s1
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n/an/a 5.60E+3n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as 4-nitrophenol release from 4-nitrophenyl alpha-D-glucopyranoside preincubated fo...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair