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5 similar compounds to monomer 50441298

Compile data set for download or QSAR
Wt: 396.3
BDBM50441321
Wt: 368.3
BDBM50441322
Wt: 354.2
BDBM50441323
Wt: 356.3
BDBM50441324
Wt: 342.2
BDBM50441327

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50441321,50441322,50441323,50441324,50441327   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
tyrosine-protein phosphatase non-receptor type 5 isoform a


(Homo sapiens (Human))
BDBM50441322
PNG
(CHEMBL2431707)
Show SMILES Oc1c(cccc1-c1cccc(c1)C(F)(F)P(O)(O)=O)C1CCCC1
Show InChI InChI=1S/C18H19F2O4P/c19-18(20,25(22,23)24)14-8-3-7-13(11-14)16-10-4-9-15(17(16)21)12-5-1-2-6-12/h3-4,7-12,21H,1-2,5-6H2,(H2,22,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.50E+4n/an/an/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis


J Med Chem 56: 7636-50 (2013)


Article DOI: 10.1021/jm401037h
BindingDB Entry DOI: 10.7270/Q2HH6MHW
More data for this
Ligand-Target Pair
tyrosine-protein phosphatase non-receptor type 5 isoform a


(Homo sapiens (Human))
BDBM50441323
PNG
(CHEMBL2431706)
Show SMILES Oc1c(cccc1-c1cccc(c1)C(F)(F)P(O)(O)=O)C1CCC1
Show InChI InChI=1S/C17H17F2O4P/c18-17(19,24(21,22)23)13-7-2-6-12(10-13)15-9-3-8-14(16(15)20)11-4-1-5-11/h2-3,6-11,20H,1,4-5H2,(H2,21,22,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.50E+4n/an/an/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis


J Med Chem 56: 7636-50 (2013)


Article DOI: 10.1021/jm401037h
BindingDB Entry DOI: 10.7270/Q2HH6MHW
More data for this
Ligand-Target Pair
tyrosine-protein phosphatase non-receptor type 5 isoform a


(Homo sapiens (Human))
BDBM50441321
PNG
(CHEMBL2431669)
Show SMILES Oc1c(cccc1-c1cccc(c1)C(F)(F)P(O)(O)=O)C1CCCCCC1
Show InChI InChI=1S/C20H23F2O4P/c21-20(22,27(24,25)26)16-10-5-9-15(13-16)18-12-6-11-17(19(18)23)14-7-3-1-2-4-8-14/h5-6,9-14,23H,1-4,7-8H2,(H2,24,25,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.20E+4n/an/an/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis


J Med Chem 56: 7636-50 (2013)


Article DOI: 10.1021/jm401037h
BindingDB Entry DOI: 10.7270/Q2HH6MHW
More data for this
Ligand-Target Pair
tyrosine-protein phosphatase non-receptor type 5 isoform a


(Homo sapiens (Human))
BDBM50441324
PNG
(CHEMBL2431705)
Show SMILES CC(C)(C)c1cccc(c1O)-c1cccc(c1)C(F)(F)P(O)(O)=O
Show InChI InChI=1S/C17H19F2O4P/c1-16(2,3)14-9-5-8-13(15(14)20)11-6-4-7-12(10-11)17(18,19)24(21,22)23/h4-10,20H,1-3H3,(H2,21,22,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.30E+4n/an/an/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis


J Med Chem 56: 7636-50 (2013)


Article DOI: 10.1021/jm401037h
BindingDB Entry DOI: 10.7270/Q2HH6MHW
More data for this
Ligand-Target Pair
tyrosine-protein phosphatase non-receptor type 5 isoform a


(Homo sapiens (Human))
BDBM50441327
PNG
(CHEMBL2431702)
Show SMILES CC(C)c1cccc(c1O)-c1cccc(c1)C(F)(F)P(O)(O)=O
Show InChI InChI=1S/C16H17F2O4P/c1-10(2)13-7-4-8-14(15(13)19)11-5-3-6-12(9-11)16(17,18)23(20,21)22/h3-10,19H,1-2H3,(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.90E+4n/an/an/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysis


J Med Chem 56: 7636-50 (2013)


Article DOI: 10.1021/jm401037h
BindingDB Entry DOI: 10.7270/Q2HH6MHW
More data for this
Ligand-Target Pair