BindingDB logo
myBDB logout

9 similar compounds to monomer 50452956

Compile data set for download or QSAR
Wt: 242.2
BDBM50452934
Purchase
Wt: 310.3
BDBM50452941
Wt: 270.3
BDBM50452963
Wt: 322.4
BDBM50452970
Wt: 308.3
BDBM50452953
Wt: 296.3
BDBM50452959
Wt: 322.4
BDBM50452972
Wt: 438.3
BDBM50452932
Wt: 256.3
BDBM50452933

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50452934,50452941,50452963,50452970,50452953,50452959,50452972,50452932,50452933   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452970
PNG
(CHEMBL36478)
Show SMILES CN1C2CCC1CC(C2)c1nc(no1)-c1cn(C)c2ccccc12
Show InChI InChI=1S/C19H22N4O/c1-22-11-16(15-5-3-4-6-17(15)22)18-20-19(24-21-18)12-9-13-7-8-14(10-12)23(13)2/h3-6,11-14H,7-10H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 191n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452941
PNG
(CHEMBL36601)
Show SMILES Cn1cc(-c2noc(CCN3CCCCC3)n2)c2ccccc12
Show InChI InChI=1S/C18H22N4O/c1-21-13-15(14-7-3-4-8-16(14)21)18-19-17(23-20-18)9-12-22-10-5-2-6-11-22/h3-4,7-8,13H,2,5-6,9-12H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 372n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452963
PNG
(CHEMBL38310)
Show SMILES CN(C)CCc1nc(no1)-c1cn(C)c2ccccc12
Show InChI InChI=1S/C15H18N4O/c1-18(2)9-8-14-16-15(17-20-14)12-10-19(3)13-7-5-4-6-11(12)13/h4-7,10H,8-9H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452932
PNG
(CHEMBL285166)
Show SMILES Cn1cc(-c2noc(n2)C2CC[N+](C)(C)CC2)c2ccccc12
Show InChI InChI=1S/C18H23N4O.HI/c1-21-12-15(14-6-4-5-7-16(14)21)17-19-18(23-20-17)13-8-10-22(2,3)11-9-13;/h4-7,12-13H,8-11H2,1-3H3;1H/q+1;/p-1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 35n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452953
PNG
(CHEMBL284101)
Show SMILES Cn1cc(-c2noc(n2)C23CCN(CC2)CC3)c2ccccc12
Show InChI InChI=1S/C18H20N4O/c1-21-12-14(13-4-2-3-5-15(13)21)16-19-17(23-20-16)18-6-9-22(10-7-18)11-8-18/h2-5,12H,6-11H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.30n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452933
PNG
(CHEMBL37365)
Show SMILES CNCCc1nc(no1)-c1cn(C)c2ccccc12
Show InChI InChI=1S/C14H16N4O/c1-15-8-7-13-16-14(17-19-13)11-9-18(2)12-6-4-3-5-10(11)12/h3-6,9,15H,7-8H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 85n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452959
PNG
(CHEMBL284523)
Show SMILES CN1CCC(CC1)c1nc(no1)-c1cn(C)c2ccccc12
Show InChI InChI=1S/C17H20N4O/c1-20-9-7-12(8-10-20)17-18-16(19-22-17)14-11-21(2)15-6-4-3-5-13(14)15/h3-6,11-12H,7-10H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452972
PNG
(CHEMBL37237)
Show SMILES Cn1cc(-c2noc(CC3CN4CCC3CC4)n2)c2ccccc12
Show InChI InChI=1S/C19H22N4O/c1-22-12-16(15-4-2-3-5-17(15)22)19-20-18(24-21-19)10-14-11-23-8-6-13(14)7-9-23/h2-5,12-14H,6-11H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 55n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452934
PNG
(CHEMBL286884)
Show SMILES Cn1cc(-c2noc(CCN)n2)c2ccccc12
Show InChI InChI=1S/C13H14N4O/c1-17-8-10(9-4-2-3-5-11(9)17)13-15-12(6-7-14)18-16-13/h2-5,8H,6-7,14H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 68n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair