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2 similar compounds to monomer 50452930

Compile data set for download or QSAR
Wt: 255.3
BDBM50452964
Wt: 306.3
BDBM50452946

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452964,50452946   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452964
PNG
(CHEMBL37309)
Show SMILES C1CN2CCC1C(C2)c1nc(no1)-c1ccccc1
Show InChI InChI=1S/C15H17N3O/c1-2-4-12(5-3-1)14-16-15(19-17-14)13-10-18-8-6-11(13)7-9-18/h1-5,11,13H,6-10H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452946
PNG
(CHEMBL36854)
Show SMILES C1CN2CCC1C(C2)c1nc(no1)-c1cnc2ccccc2c1
Show InChI InChI=1S/C18H18N4O/c1-2-4-16-13(3-1)9-14(10-19-16)17-20-18(23-21-17)15-11-22-7-5-12(15)6-8-22/h1-4,9-10,12,15H,5-8,11H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.51E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair