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5 similar compounds to monomer 44997

Compile data set for download or QSAR
Wt: 268.2
BDBM52507
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Wt: 374.3
BDBM54311
Wt: 360.3
BDBM57357
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Wt: 330.3
BDBM114706
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Wt: 374.3
BDBM50384142
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 52507,54311,57357,114706,50384142   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
POsterior Segregation family member (pos-1)


(Caenorhabditis elegans)
BDBM52507
PNG
((3E)-2-amino-5-methyl-3-(phenylhydrazinylidene)-7-...)
Show SMILES Cc1cc(=O)n2[nH]c(N)c(N=Nc3ccccc3)c2n1
Show InChI InChI=1S/C13H12N6O/c1-8-7-10(20)19-13(15-8)11(12(14)18-19)17-16-9-5-3-2-4-6-9/h2-7,18H,14H2,1H3
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PCBioAssay
n/an/an/an/a 3.78E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q28G8J4C
More data for this
Ligand-Target Pair
RecName: Full=Zinc finger protein mex-5


(Caenorhabditis elegans)
BDBM52507
PNG
((3E)-2-amino-5-methyl-3-(phenylhydrazinylidene)-7-...)
Show SMILES Cc1cc(=O)n2[nH]c(N)c(N=Nc3ccccc3)c2n1
Show InChI InChI=1S/C13H12N6O/c1-8-7-10(20)19-13(15-8)11(12(14)18-19)17-16-9-5-3-2-4-6-9/h2-7,18H,14H2,1H3
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n/an/an/an/a 1.52E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2D798VP
More data for this
Ligand-Target Pair
nucleotide-binding oligomerization domain containing 2


(Homo sapiens)
BDBM54311
PNG
((3E)-2-amino-3-(1,3-benzodioxol-5-ylhydrazinyliden...)
Show SMILES Nc1[nH]n2c(nc(cc2=O)-c2ccccc2)c1N=Nc1ccc2OCOc2c1
Show InChI InChI=1S/C19H14N6O3/c20-18-17(23-22-12-6-7-14-15(8-12)28-10-27-14)19-21-13(9-16(26)25(19)24-18)11-4-2-1-3-5-11/h1-9,24H,10,20H2
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n/an/a 1.45E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q23R0R8T
More data for this
Ligand-Target Pair
X-linked inhibitor of apoptosis protein (XIAP)


(Homo sapiens (Human))
BDBM52507
PNG
((3E)-2-amino-5-methyl-3-(phenylhydrazinylidene)-7-...)
Show SMILES Cc1cc(=O)n2[nH]c(N)c(N=Nc3ccccc3)c2n1
Show InChI InChI=1S/C13H12N6O/c1-8-7-10(20)19-13(15-8)11(12(14)18-19)17-16-9-5-3-2-4-6-9/h2-7,18H,14H2,1H3
PDB

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n/an/a 1.00E+5n/an/an/an/an/an/a



Sanford-Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2HD7T4S
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (human))
BDBM50384142
PNG
(CHEMBL2029700)
Show SMILES Nc1[nH]n2c(nc(cc2=O)-c2ccccc2)c1N=Nc1ccc2OCOc2c1
Show InChI InChI=1S/C19H14N6O3/c20-18-17(23-22-12-6-7-14-15(8-12)28-10-27-14)19-21-13(9-16(26)25(19)24-18)11-4-2-1-3-5-11/h1-9,24H,10,20H2
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CHEMBL
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Article
PubMed
n/an/a 5.30E+3n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of EGFR after 50 mins by HTRF assay


Bioorg Med Chem Lett 22: 4004-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.092
BindingDB Entry DOI: 10.7270/Q2DF6S7R
More data for this
Ligand-Target Pair
streptokinase A precursor


(Streptococcus pyogenes M1 GAS)
BDBM57357
PNG
((3E)-2-amino-3-[(3-methoxyphenyl)hydrazinylidene]-...)
Show SMILES COc1cccc(c1)N=Nc1c(N)[nH]n2c1nc(cc2=O)-c1ccccc1
Show InChI InChI=1S/C19H16N6O2/c1-27-14-9-5-8-13(10-14)22-23-17-18(20)24-25-16(26)11-15(21-19(17)25)12-6-3-2-4-7-12/h2-11,24H,20H2,1H3
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n/an/an/an/a 1.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2736PBV
More data for this
Ligand-Target Pair
Tumor necrosis factor


(Homo sapiens (Human))
BDBM54311
PNG
((3E)-2-amino-3-(1,3-benzodioxol-5-ylhydrazinyliden...)
Show SMILES Nc1[nH]n2c(nc(cc2=O)-c2ccccc2)c1N=Nc1ccc2OCOc2c1
Show InChI InChI=1S/C19H14N6O3/c20-18-17(23-22-12-6-7-14-15(8-12)28-10-27-14)19-21-13(9-16(26)25(19)24-18)11-4-2-1-3-5-11/h1-9,24H,10,20H2
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n/an/a 2.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q25M6443
More data for this
Ligand-Target Pair
protein artemis isoform a


(Homo sapiens)
BDBM114706
PNG
((3E)-2-amino-5-phenyl-3-(phenylhydrazinylidene)-7-...)
Show SMILES Nc1[nH]n2c(nc(cc2=O)-c2ccccc2)c1N=Nc1ccccc1
Show InChI InChI=1S/C18H14N6O/c19-17-16(22-21-13-9-5-2-6-10-13)18-20-14(11-15(25)24(18)23-17)12-7-3-1-4-8-12/h1-11,23H,19H2
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n/an/a 1.99E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...


PubChem Bioassay (2013)


BindingDB Entry DOI: 10.7270/Q2MC8XP5
More data for this
Ligand-Target Pair
nucleotide-binding oligomerization domain containing 1


(Homo sapiens)
BDBM54311
PNG
((3E)-2-amino-3-(1,3-benzodioxol-5-ylhydrazinyliden...)
Show SMILES Nc1[nH]n2c(nc(cc2=O)-c2ccccc2)c1N=Nc1ccc2OCOc2c1
Show InChI InChI=1S/C19H14N6O3/c20-18-17(23-22-12-6-7-14-15(8-12)28-10-27-14)19-21-13(9-16(26)25(19)24-18)11-4-2-1-3-5-11/h1-9,24H,10,20H2
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n/an/an/an/a 1.84E+4n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2CN72C0
More data for this
Ligand-Target Pair