BindingDB logo
myBDB logout

2 similar compounds to monomer 50290849

Compile data set for download or QSAR
Wt: 370.3
BDBM6511
Purchase
Wt: 360.4
BDBM97006
Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6511,97006   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Probable global transcription activator SNF2L2


(Homo sapiens (Human))
BDBM97006
PNG
(MLS001198520 | N-(3,4,5-trimethoxyphenyl)-9-acridi...)
Show SMILES COc1cc(Nc2c3ccccc3nc3ccccc23)cc(OC)c1OC
Show InChI InChI=1S/C22H20N2O3/c1-25-19-12-14(13-20(26-2)22(19)27-3)23-21-15-8-4-6-10-17(15)24-18-11-7-5-9-16(18)21/h4-13H,1-3H3,(H,23,24)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 9.12E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay




PubChem Bioassay (2013)


BindingDB Entry DOI: 10.7270/Q2GF0S4R
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM6511
PNG
(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
Show SMILES COc1cc(Nc2ccnc3cc(OC)c(OC)cc23)cc(OC)c1OC
Show InChI InChI=1S/C20H22N2O5/c1-23-16-10-13-14(6-7-21-15(13)11-17(16)24-2)22-12-8-18(25-3)20(27-5)19(9-12)26-4/h6-11H,1-5H3,(H,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/a7.530



Wyeth-Ayerst Research



Assay Description
Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...


Bioorg Med Chem Lett 10: 2477-80 (2000)


Article DOI: 10.1016/S0960-894X(00)00493-5
BindingDB Entry DOI: 10.7270/Q20P0X7T
More data for this
Ligand-Target Pair