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7 similar compounds to monomer 150749

Wt: 342.3
BDBM65837
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Wt: 416.4
BDBM67493
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Wt: 372.4
BDBM67506
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Wt: 342.3
BDBM67460
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Wt: 326.3
BDBM67462
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Wt: 356.4
BDBM67472
Wt: 312.3
BDBM67524
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 65837,67493,67506,67460,67462,67472,67524   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NADPH oxidase 1


(Homo sapiens)
BDBM65837
PNG
(4-(4,5-diphenyl-1,3-dihydroimidazol-2-ylidene)-2-m...)
Show SMILES COc1cc(ccc1O)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C22H18N2O2/c1-26-19-14-17(12-13-18(19)25)22-23-20(15-8-4-2-5-9-15)21(24-22)16-10-6-3-7-11-16/h2-14,25H,1H3,(H,23,24)
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n/an/a 1.81E+3n/an/an/an/an/an/a



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More data for this
Ligand-Target Pair
NADPH oxidase 1


(Homo sapiens)
BDBM65837
PNG
(4-(4,5-diphenyl-1,3-dihydroimidazol-2-ylidene)-2-m...)
Show SMILES COc1cc(ccc1O)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C22H18N2O2/c1-26-19-14-17(12-13-18(19)25)22-23-20(15-8-4-2-5-9-15)21(24-22)16-10-6-3-7-11-16/h2-14,25H,1H3,(H,23,24)
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n/an/a 1.12E+4n/an/an/an/an/an/a



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More data for this
Ligand-Target Pair
NADPH oxidase 1


(Homo sapiens)
BDBM65837
PNG
(4-(4,5-diphenyl-1,3-dihydroimidazol-2-ylidene)-2-m...)
Show SMILES COc1cc(ccc1O)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C22H18N2O2/c1-26-19-14-17(12-13-18(19)25)22-23-20(15-8-4-2-5-9-15)21(24-22)16-10-6-3-7-11-16/h2-14,25H,1H3,(H,23,24)
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More data for this
Ligand-Target Pair
NADPH oxidase 1


(Homo sapiens)
BDBM65837
PNG
(4-(4,5-diphenyl-1,3-dihydroimidazol-2-ylidene)-2-m...)
Show SMILES COc1cc(ccc1O)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C22H18N2O2/c1-26-19-14-17(12-13-18(19)25)22-23-20(15-8-4-2-5-9-15)21(24-22)16-10-6-3-7-11-16/h2-14,25H,1H3,(H,23,24)
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More data for this
Ligand-Target Pair
NADPH oxidase 1


(Homo sapiens)
BDBM67460
PNG
(5-(4,5-diphenyl-1H-imidazol-2-yl)-2-methoxy-phenol...)
Show SMILES COc1ccc(cc1O)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C22H18N2O2/c1-26-19-13-12-17(14-18(19)25)22-23-20(15-8-4-2-5-9-15)21(24-22)16-10-6-3-7-11-16/h2-14,25H,1H3,(H,23,24)
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n/an/a>1.70E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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More data for this
Ligand-Target Pair
NADPH oxidase 1


(Homo sapiens)
BDBM67462
PNG
(2-(3-methoxyphenyl)-4,5-diphenyl-1H-imidazole | SR...)
Show SMILES COc1cccc(c1)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C22H18N2O/c1-25-19-14-8-13-18(15-19)22-23-20(16-9-4-2-5-10-16)21(24-22)17-11-6-3-7-12-17/h2-15H,1H3,(H,23,24)
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The Scripps Research Institute Molecular Screening Center

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More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM67462
PNG
(2-(3-methoxyphenyl)-4,5-diphenyl-1H-imidazole | SR...)
Show SMILES COc1cccc(c1)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C22H18N2O/c1-25-19-14-8-13-18(15-19)22-23-20(16-9-4-2-5-10-16)21(24-22)17-11-6-3-7-12-17/h2-15H,1H3,(H,23,24)
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PubMed
n/an/a 3.59E+5n/an/an/an/an/a37



COMSATS Institute of Information Technology



Assay Description
A 100 無 assay mixture containing 70 無 phosphate buffer saline (50 mM at pH 6.8), 10 無 corresponding test compounds dissolved in methanol/DMSO (0.5...


Bioorg Chem 58: 65-71 (2015)

More data for this
Ligand-Target Pair
NADPH oxidase 1


(Homo sapiens)
BDBM67493
PNG
(2-(3,4-dimethoxyphenyl)-4,5-bis(4-methoxyphenyl)-1...)
Show SMILES COc1ccc(cc1)-c1nc([nH]c1-c1ccc(OC)cc1)-c1ccc(OC)c(OC)c1
Show InChI InChI=1S/C25H24N2O4/c1-28-19-10-5-16(6-11-19)23-24(17-7-12-20(29-2)13-8-17)27-25(26-23)18-9-14-21(30-3)22(15-18)31-4/h5-15H,1-4H3,(H,26,27)
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The Scripps Research Institute Molecular Screening Center

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More data for this
Ligand-Target Pair
NADPH oxidase 1


(Homo sapiens)
BDBM67506
PNG
(4-(4,5-diphenyl-1,3-dihydroimidazol-2-ylidene)-2,6...)
Show SMILES COc1cc(cc(OC)c1O)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C23H20N2O3/c1-27-18-13-17(14-19(28-2)22(18)26)23-24-20(15-9-5-3-6-10-15)21(25-23)16-11-7-4-8-12-16/h3-14,26H,1-2H3,(H,24,25)
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The Scripps Research Institute Molecular Screening Center

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More data for this
Ligand-Target Pair
NADPH oxidase 1


(Homo sapiens)
BDBM67524
PNG
(6-(4,5-diphenyl-1,3-dihydroimidazol-2-ylidene)-1-c...)
Show SMILES Oc1ccccc1-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H16N2O/c24-18-14-8-7-13-17(18)21-22-19(15-9-3-1-4-10-15)20(23-21)16-11-5-2-6-12-16/h1-14,24H,(H,22,23)
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n/an/a>1.70E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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More data for this
Ligand-Target Pair
NADPH oxidase 1


(Homo sapiens)
BDBM65837
PNG
(4-(4,5-diphenyl-1,3-dihydroimidazol-2-ylidene)-2-m...)
Show SMILES COc1cc(ccc1O)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C22H18N2O2/c1-26-19-14-17(12-13-18(19)25)22-23-20(15-8-4-2-5-9-15)21(24-22)16-10-6-3-7-11-16/h2-14,25H,1H3,(H,23,24)
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n/an/a 10n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...


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More data for this
Ligand-Target Pair
NADPH oxidase 1


(Homo sapiens)
BDBM67506
PNG
(4-(4,5-diphenyl-1,3-dihydroimidazol-2-ylidene)-2,6...)
Show SMILES COc1cc(cc(OC)c1O)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C23H20N2O3/c1-27-18-13-17(14-19(28-2)22(18)26)23-24-20(15-9-5-3-6-10-15)21(25-23)16-11-7-4-8-12-16/h3-14,26H,1-2H3,(H,24,25)
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The Scripps Research Institute Molecular Screening Center

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More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM67524
PNG
(6-(4,5-diphenyl-1,3-dihydroimidazol-2-ylidene)-1-c...)
Show SMILES Oc1ccccc1-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H16N2O/c24-18-14-8-7-13-17(18)21-22-19(15-9-3-1-4-10-15)20(23-21)16-11-5-2-6-12-16/h1-14,24H,(H,22,23)
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n/an/a 7.43E+4n/an/an/an/an/a37



COMSATS Institute of Information Technology



Assay Description
A 100 無 assay mixture containing 70 無 phosphate buffer saline (50 mM at pH 6.8), 10 無 corresponding test compounds dissolved in methanol/DMSO (0.5...


Bioorg Chem 58: 65-71 (2015)

More data for this
Ligand-Target Pair
NADPH oxidase 1


(Homo sapiens)
BDBM67472
PNG
(2-(3,4-dimethoxyphenyl)-4,5-diphenyl-1H-imidazole ...)
Show SMILES COc1ccc(cc1OC)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C23H20N2O2/c1-26-19-14-13-18(15-20(19)27-2)23-24-21(16-9-5-3-6-10-16)22(25-23)17-11-7-4-8-12-17/h3-15H,1-2H3,(H,24,25)
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The Scripps Research Institute Molecular Screening Center

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More data for this
Ligand-Target Pair