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13 similar compounds to monomer 173530

Wt: 369.3
BDBM79576
Wt: 339.3
BDBM95431
Purchase
Wt: 345.3
BDBM50104098
Wt: 295.2
BDBM173533
Wt: 295.2
BDBM173534
Wt: 295.2
BDBM173535
Wt: 309.3
BDBM173536
Purchase
Wt: 279.2
BDBM173537
Purchase
Wt: 279.2
BDBM173538
Wt: 309.3
BDBM173539
Wt: 309.3
BDBM173540
Wt: 311.2
BDBM173531
Wt: 295.2
BDBM173532

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 79576,95431,50104098,173533,173534,173535,173536,173537,173538,173539,173540,173531,173532   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine receptor D2L/neurotensin receptor NTS1


(Homo sapiens)
BDBM79576
PNG
(4,6-Dimethoxy-1H-indole-2-carboxylic acid [1-(2-hy...)
Show SMILES COc1cc(OC)c2cc([nH]c2c1)C(=O)NN=Cc1cccc(OC)c1O
Show InChI InChI=1S/C19H19N3O5/c1-25-12-7-14-13(17(8-12)27-3)9-15(21-14)19(24)22-20-10-11-5-4-6-16(26-2)18(11)23/h4-10,21,23H,1-3H3,(H,22,24)/b20-10+
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n/an/an/an/a 1.93E+4n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


Citation and Details
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM50104098
PNG
(5-Hydroxy-1H-indole-2-carboxylic acid (4-hydroxy-n...)
Show SMILES Oc1ccc2[nH]c(cc2c1)C(=O)N\N=C\c1ccc(O)c2ccccc12
Show InChI InChI=1S/C20H15N3O3/c24-14-6-7-17-13(9-14)10-18(22-17)20(26)23-21-11-12-5-8-19(25)16-4-2-1-3-15(12)16/h1-11,22,24-25H,(H,23,26)/b21-11+
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n/an/a>1.00E+5n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Binding affinity for human Glucagon Receptor


Citation and Details
More data for this
Ligand-Target Pair
Nuclear receptor coactivator 1


(Homo sapiens)
BDBM79576
PNG
(4,6-Dimethoxy-1H-indole-2-carboxylic acid [1-(2-hy...)
Show SMILES COc1cc(OC)c2cc([nH]c2c1)C(=O)NN=Cc1cccc(OC)c1O
Show InChI InChI=1S/C19H19N3O5/c1-25-12-7-14-13(17(8-12)27-3)9-15(21-14)19(24)22-20-10-11-5-4-6-16(26-2)18(11)23/h4-10,21,23H,1-3H3,(H,22,24)/b20-10+
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n/an/a 1.15E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


Citation and Details
More data for this
Ligand-Target Pair
MSRA protein


(Bos taurus)
BDBM95431
PNG
(5-methoxy-N-[(E)-(4-methoxy-3-oxidanyl-phenyl)meth...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)N\N=C\c1ccc(OC)c(O)c1
Show InChI InChI=1S/C18H17N3O4/c1-24-13-4-5-14-12(8-13)9-15(20-14)18(23)21-19-10-11-3-6-17(25-2)16(22)7-11/h3-10,20,22H,1-2H3,(H,21,23)/b19-10+
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n/an/a>1.55E+5n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay




Citation and Details
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM173531
PNG
((E)-N'-(2,4,6-trihydroxybenzylidene)-1H-indole...)
Show SMILES Oc1cc(O)c(\C=N\NC(=O)c2cc3ccccc3[nH]2)c(O)c1
Show InChI InChI=1S/C16H13N3O4/c20-10-6-14(21)11(15(22)7-10)8-17-19-16(23)13-5-9-3-1-2-4-12(9)18-13/h1-8,18,20-22H,(H,19,23)/b17-8+
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n/an/a 4.92E+4n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM)



Assay Description
The 135 無 of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 無 of test sample with 70% DMSO added into the wells. The ...


Bioorg Chem 63: 24-35 (2015)

More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM173532
PNG
((E)-N'-(2,5-dihydroxybenzylidene)-1H-indole-2-...)
Show SMILES Oc1ccc(O)c(\C=N\NC(=O)c2cc3ccccc3[nH]2)c1
Show InChI InChI=1S/C16H13N3O3/c20-12-5-6-15(21)11(7-12)9-17-19-16(22)14-8-10-3-1-2-4-13(10)18-14/h1-9,18,20-21H,(H,19,22)/b17-9+
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n/an/a 1.44E+5n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM)



Assay Description
The 135 無 of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 無 of test sample with 70% DMSO added into the wells. The ...


Bioorg Chem 63: 24-35 (2015)

More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM173533
PNG
((E)-N'-(3,4-dihydroxybenzylidene)-1H-indole-2-...)
Show SMILES Oc1ccc(\C=N\NC(=O)c2cc3ccccc3[nH]2)cc1O
Show InChI InChI=1S/C16H13N3O3/c20-14-6-5-10(7-15(14)21)9-17-19-16(22)13-8-11-3-1-2-4-12(11)18-13/h1-9,18,20-21H,(H,19,22)/b17-9+
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n/an/a 4.10E+4n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM)



Assay Description
The 135 無 of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 無 of test sample with 70% DMSO added into the wells. The ...


Bioorg Chem 63: 24-35 (2015)

More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM173534
PNG
((E)-N'-(2,3-dihydroxybenzylidene)-1H-indole-2-...)
Show SMILES Oc1cccc(\C=N\NC(=O)c2cc3ccccc3[nH]2)c1O
Show InChI InChI=1S/C16H13N3O3/c20-14-7-3-5-11(15(14)21)9-17-19-16(22)13-8-10-4-1-2-6-12(10)18-13/h1-9,18,20-21H,(H,19,22)/b17-9+
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n/an/a 8.65E+4n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM)



Assay Description
The 135 無 of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 無 of test sample with 70% DMSO added into the wells. The ...


Bioorg Chem 63: 24-35 (2015)

More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM173535
PNG
((E)-N'-(3,5-dihydroxybenzylidene)-1H-indole-2-...)
Show SMILES Oc1cc(O)cc(\C=N\NC(=O)c2cc3ccccc3[nH]2)c1
Show InChI InChI=1S/C16H13N3O3/c20-12-5-10(6-13(21)8-12)9-17-19-16(22)15-7-11-3-1-2-4-14(11)18-15/h1-9,18,20-21H,(H,19,22)/b17-9+
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n/an/a 2.26E+5n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM)



Assay Description
The 135 無 of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 無 of test sample with 70% DMSO added into the wells. The ...


Bioorg Chem 63: 24-35 (2015)

More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM173536
PNG
((E)-N'-(4-hydroxy-3-methoxybenzylidene)-1H-ind...)
Show SMILES COc1cc(\C=N\NC(=O)c2cc3ccccc3[nH]2)ccc1O
Show InChI InChI=1S/C17H15N3O3/c1-23-16-8-11(6-7-15(16)21)10-18-20-17(22)14-9-12-4-2-3-5-13(12)19-14/h2-10,19,21H,1H3,(H,20,22)/b18-10+
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n/an/a 1.55E+5n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM)



Assay Description
The 135 無 of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 無 of test sample with 70% DMSO added into the wells. The ...


Bioorg Chem 63: 24-35 (2015)

More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM173537
PNG
((E)-N'-(4-hydroxybenzylidene)-1H-indole-2-carb...)
Show SMILES Oc1ccc(\C=N\NC(=O)c2cc3ccccc3[nH]2)cc1
Show InChI InChI=1S/C16H13N3O2/c20-13-7-5-11(6-8-13)10-17-19-16(21)15-9-12-3-1-2-4-14(12)18-15/h1-10,18,20H,(H,19,21)/b17-10+
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n/an/a 2.06E+5n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM)



Assay Description
The 135 無 of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 無 of test sample with 70% DMSO added into the wells. The ...


Bioorg Chem 63: 24-35 (2015)

More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM173538
PNG
((E)-N'-(2-hydroxybenzylidene)-1H-indole-2-carb...)
Show SMILES Oc1ccccc1\C=N\NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C16H13N3O2/c20-15-8-4-2-6-12(15)10-17-19-16(21)14-9-11-5-1-3-7-13(11)18-14/h1-10,18,20H,(H,19,21)/b17-10+
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n/an/a 4.26E+4n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM)



Assay Description
The 135 無 of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 無 of test sample with 70% DMSO added into the wells. The ...


Bioorg Chem 63: 24-35 (2015)

More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM173539
PNG
((E)-N'-(3-hydroxy-4-methoxybenzylidene)-1H-ind...)
Show SMILES COc1ccc(\C=N\NC(=O)c2cc3ccccc3[nH]2)cc1O
Show InChI InChI=1S/C17H15N3O3/c1-23-16-7-6-11(8-15(16)21)10-18-20-17(22)14-9-12-4-2-3-5-13(12)19-14/h2-10,19,21H,1H3,(H,20,22)/b18-10+
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n/an/a 1.91E+5n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM)



Assay Description
The 135 無 of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 無 of test sample with 70% DMSO added into the wells. The ...


Bioorg Chem 63: 24-35 (2015)

More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM173540
PNG
((E)-N'-(2-hydroxy-5-methoxybenzylidene)-1H-ind...)
Show SMILES COc1ccc(O)c(\C=N\NC(=O)c2cc3ccccc3[nH]2)c1
Show InChI InChI=1S/C17H15N3O3/c1-23-13-6-7-16(21)12(8-13)10-18-20-17(22)15-9-11-4-2-3-5-14(11)19-15/h2-10,19,21H,1H3,(H,20,22)/b18-10+
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n/an/a 4.92E+4n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM)



Assay Description
The 135 無 of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 無 of test sample with 70% DMSO added into the wells. The ...


Bioorg Chem 63: 24-35 (2015)

More data for this
Ligand-Target Pair
nuclear receptor coactivator 3 isoform a


(Homo sapiens)
BDBM79576
PNG
(4,6-Dimethoxy-1H-indole-2-carboxylic acid [1-(2-hy...)
Show SMILES COc1cc(OC)c2cc([nH]c2c1)C(=O)NN=Cc1cccc(OC)c1O
Show InChI InChI=1S/C19H19N3O5/c1-25-12-7-14-13(17(8-12)27-3)9-15(21-14)19(24)22-20-10-11-5-4-6-16(26-2)18(11)23/h4-10,21,23H,1-3H3,(H,22,24)/b20-10+
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n/an/a 3.56E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


Citation and Details
More data for this
Ligand-Target Pair