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3 similar compounds to monomer 50079183

Compile data set for download or QSAR
Wt: 167.1
BDBM82252
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Wt: 167.1
BDBM50053589
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Wt: 167.1
BDBM50089914
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 82252,50053589,50089914   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50053589
PNG
((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
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8.40E+3n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche

Curated by PDSP Ki Database




J Neurochem 75: 2590-601 (2000)


Article DOI: 10.1046/j.1471-4159.2000.0752590.x
BindingDB Entry DOI: 10.7270/Q2J67FGZ
More data for this
Ligand-Target Pair
Glutamate kainate


(RAT)
BDBM82252
PNG
((R)-3-Hydroxyphenylglyci)
Show SMILES N[C@@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/s2
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Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Glutamate kainate


(RAT)
BDBM50053589
PNG
((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
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Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT)
BDBM82252
PNG
((R)-3-Hydroxyphenylglyci)
Show SMILES N[C@@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/s2
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Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT)
BDBM50053589
PNG
((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
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Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor


(RAT)
BDBM82252
PNG
((R)-3-Hydroxyphenylglyci)
Show SMILES N[C@@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/s2
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Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor


(RAT)
BDBM82252
PNG
((R)-3-Hydroxyphenylglyci)
Show SMILES N[C@@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/s2
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Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor


(RAT)
BDBM50053589
PNG
((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
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Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor


(RAT)
BDBM50053589
PNG
((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
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Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM82252
PNG
((R)-3-Hydroxyphenylglyci)
Show SMILES N[C@@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/s2
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Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50053589
PNG
((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
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Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50053589
PNG
((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM82252
PNG
((R)-3-Hydroxyphenylglyci)
Show SMILES N[C@@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/s2
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>1.00E+4n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50053589
PNG
((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50053589
PNG
((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Emory University

Curated by PDSP Ki Database




Annu Rev Pharmacol Toxicol 37: 205-37 (1997)


Article DOI: 10.1146/annurev.pharmtox.37.1.205
BindingDB Entry DOI: 10.7270/Q2M043ZH
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50053589
PNG
((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Emory University

Curated by PDSP Ki Database




Annu Rev Pharmacol Toxicol 37: 205-37 (1997)


Article DOI: 10.1146/annurev.pharmtox.37.1.205
BindingDB Entry DOI: 10.7270/Q2M043ZH
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50053589
PNG
((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche

Curated by PDSP Ki Database




J Neurochem 75: 2590-601 (2000)


Article DOI: 10.1046/j.1471-4159.2000.0752590.x
BindingDB Entry DOI: 10.7270/Q2J67FGZ
More data for this
Ligand-Target Pair
GRIA3


(RAT)
BDBM82252
PNG
((R)-3-Hydroxyphenylglyci)
Show SMILES N[C@@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/s2
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>1.00E+4n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
GRIA3


(RAT)
BDBM50053589
PNG
((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by PDSP Ki Database




Eur J Pharmacol 267: 77-84 (1994)


Article DOI: 10.1016/0922-4106(94)90227-5
BindingDB Entry DOI: 10.7270/Q2RX99MZ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50089914
PNG
(Amino-(3-hydroxy-phenyl)-acetic acid(S-HPG) | CHEM...)
Show SMILES NC(C(O)=O)c1cccc(O)c1
Show InChI InChI=1/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)
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1.40E+4n/an/an/an/an/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Agonist potency against cloned metabotropic glutamate receptor 5


J Med Chem 43: 2609-45 (2000)


Article DOI: 10.1021/jm000007r
BindingDB Entry DOI: 10.7270/Q2DZ090Q
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50089914
PNG
(Amino-(3-hydroxy-phenyl)-acetic acid(S-HPG) | CHEM...)
Show SMILES NC(C(O)=O)c1cccc(O)c1
Show InChI InChI=1/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)
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>1.00E+6n/an/an/an/an/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).


J Med Chem 43: 2609-45 (2000)


Article DOI: 10.1021/jm000007r
BindingDB Entry DOI: 10.7270/Q2DZ090Q
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50089914
PNG
(Amino-(3-hydroxy-phenyl)-acetic acid(S-HPG) | CHEM...)
Show SMILES NC(C(O)=O)c1cccc(O)c1
Show InChI InChI=1/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)
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1.00E+6n/an/an/an/an/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Agonist potency against cloned human metabotropic glutamate receptor 1


J Med Chem 43: 2609-45 (2000)


Article DOI: 10.1021/jm000007r
BindingDB Entry DOI: 10.7270/Q2DZ090Q
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50089914
PNG
(Amino-(3-hydroxy-phenyl)-acetic acid(S-HPG) | CHEM...)
Show SMILES NC(C(O)=O)c1cccc(O)c1
Show InChI InChI=1/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)
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>1.00E+6n/an/an/an/an/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)


J Med Chem 43: 2609-45 (2000)


Article DOI: 10.1021/jm000007r
BindingDB Entry DOI: 10.7270/Q2DZ090Q
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50053589
PNG
((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
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n/an/an/an/a 6.80E+4n/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Effective concentration of the compound for half maximal stimulation of PI hydrolysis (mGluR1a)


J Med Chem 39: 3998-4006 (1996)


Article DOI: 10.1021/jm9601718
BindingDB Entry DOI: 10.7270/Q2765DFJ
More data for this
Ligand-Target Pair