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5 similar compounds to monomer 84469

Wt: 257.2
BDBM84470
Wt: 273.7
BDBM84471
Wt: 318.1
BDBM84472
Wt: 237.2
BDBM50104399
Wt: 251.3
BDBM50118920

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 84470,84471,84472,50104399,50118920   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-L-fucosidase I


(Homo sapiens)
BDBM50118920
PNG
((1R,2S,3S)-4-Benzylamino-6-methyl-cyclohexane-1,2,...)
Show SMILES CC1CC(NCc2ccccc2)C(O)C(O)C1O
Show InChI InChI=1S/C14H21NO3/c1-9-7-11(13(17)14(18)12(9)16)15-8-10-5-3-2-4-6-10/h2-6,9,11-18H,7-8H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
69n/an/an/an/an/an/an/an/a



Keio University

Curated by ChEMBL


Assay Description
Binding affinity against alpha-L-fucosidase in bovine kidney was determined


Citation and Details
More data for this
Ligand-Target Pair
Golgi alpha-mannosidase II


(Homo sapiens (Human))
BDBM84472
PNG
(Aminocyclopentitetrol, 2e)
Show SMILES O[C@H]1[C@@H](O)[C@@H](O)[C@@H](NCc2ccc(Br)cc2)[C@H]1O
Show InChI InChI=1S/C12H16BrNO4/c13-7-3-1-6(2-4-7)5-14-8-9(15)11(17)12(18)10(8)16/h1-4,8-12,14-18H,5H2/t8-,9+,10-,11+,12-
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
330 -9.19n/an/an/an/an/a5.637



University of Georgia





Chembiochem 5: 1220-7 (2004)

More data for this
Ligand-Target Pair
Golgi alpha-mannosidase II


(Homo sapiens (Human))
BDBM84470
PNG
(Aminocyclopentitetrol, 2c)
Show SMILES O[C@H]1[C@@H](O)[C@@H](O)[C@@H](NCc2ccc(F)cc2)[C@H]1O
Show InChI InChI=1S/C12H16FNO4/c13-7-3-1-6(2-4-7)5-14-8-9(15)11(17)12(18)10(8)16/h1-4,8-12,14-18H,5H2/t8-,9+,10-,11+,12-
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
330 -9.19n/an/an/an/an/a5.637



University of Georgia





Chembiochem 5: 1220-7 (2004)

More data for this
Ligand-Target Pair
Golgi alpha-mannosidase II


(Homo sapiens (Human))
BDBM84471
PNG
(Aminocyclopentitetrol, 2d)
Show SMILES O[C@H]1[C@@H](O)[C@@H](O)[C@@H](NCc2ccc(Cl)cc2)[C@H]1O
Show InChI InChI=1S/C12H16ClNO4/c13-7-3-1-6(2-4-7)5-14-8-9(15)11(17)12(18)10(8)16/h1-4,8-12,14-18H,5H2/t8-,9+,10-,11+,12-
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
670 -8.76n/an/an/an/an/a5.637



University of Georgia





Chembiochem 5: 1220-7 (2004)

More data for this
Ligand-Target Pair
Alpha-L-fucosidase I


(Homo sapiens)
BDBM50104399
PNG
((R)-4-Benzylamino-5-methyl-cyclopentane-1,2,3-trio...)
Show SMILES CC1C(O)[C@@H](O)C(O)C1NCc1ccccc1
Show InChI InChI=1S/C13H19NO3/c1-8-10(12(16)13(17)11(8)15)14-7-9-5-3-2-4-6-9/h2-6,8,10-17H,7H2,1H3/t8?,10?,11?,12?,13-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
680n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.


Citation and Details
More data for this
Ligand-Target Pair
Golgi alpha-mannosidase II


(Homo sapiens (Human))
BDBM84470
PNG
(Aminocyclopentitetrol, 2c)
Show SMILES O[C@H]1[C@@H](O)[C@@H](O)[C@@H](NCc2ccc(F)cc2)[C@H]1O
Show InChI InChI=1S/C12H16FNO4/c13-7-3-1-6(2-4-7)5-14-8-9(15)11(17)12(18)10(8)16/h1-4,8-12,14-18H,5H2/t8-,9+,10-,11+,12-
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.00E+3 -7.41n/an/an/an/an/a5.637



University of Georgia





Chembiochem 5: 1220-7 (2004)

More data for this
Ligand-Target Pair
Golgi alpha-mannosidase II


(Homo sapiens (Human))
BDBM84472
PNG
(Aminocyclopentitetrol, 2e)
Show SMILES O[C@H]1[C@@H](O)[C@@H](O)[C@@H](NCc2ccc(Br)cc2)[C@H]1O
Show InChI InChI=1S/C12H16BrNO4/c13-7-3-1-6(2-4-7)5-14-8-9(15)11(17)12(18)10(8)16/h1-4,8-12,14-18H,5H2/t8-,9+,10-,11+,12-
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
7.60E+3 -7.26n/an/an/an/an/a5.637



University of Georgia





Chembiochem 5: 1220-7 (2004)

More data for this
Ligand-Target Pair
Golgi alpha-mannosidase II


(Homo sapiens (Human))
BDBM84471
PNG
(Aminocyclopentitetrol, 2d)
Show SMILES O[C@H]1[C@@H](O)[C@@H](O)[C@@H](NCc2ccc(Cl)cc2)[C@H]1O
Show InChI InChI=1S/C12H16ClNO4/c13-7-3-1-6(2-4-7)5-14-8-9(15)11(17)12(18)10(8)16/h1-4,8-12,14-18H,5H2/t8-,9+,10-,11+,12-
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
8.10E+3 -7.22n/an/an/an/an/a5.637



University of Georgia





Chembiochem 5: 1220-7 (2004)

More data for this
Ligand-Target Pair
Alpha-L-fucosidase I


(Homo sapiens)
BDBM50118920
PNG
((1R,2S,3S)-4-Benzylamino-6-methyl-cyclohexane-1,2,...)
Show SMILES CC1CC(NCc2ccccc2)C(O)C(O)C1O
Show InChI InChI=1S/C14H21NO3/c1-9-7-11(13(17)14(18)12(9)16)15-8-10-5-3-2-4-6-10/h2-6,9,11-18H,7-8H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Keio University

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase


Citation and Details
More data for this
Ligand-Target Pair