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1 similar compounds to monomer 84544

Compile data set for download or QSAR
Wt: 647.6
BDBM84543

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 84543   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-dependent kinase 2


(Homo sapiens (Human))
BDBM84543
PNG
(Indirubin derivative, 25)
Show SMILES CN(C)CCN(C)S(=O)(=O)c1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\OCCO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2c1
Show InChI InChI=1/C29H37N5O10S/c1-33(2)10-11-34(3)45(40,41)16-8-9-20-18(14-16)22(28(39)31-20)24-23(17-6-4-5-7-19(17)30-24)32-43-13-12-42-29-27(38)26(37)25(36)21(15-35)44-29/h4-9,14,21,25-27,29-30,35-38H,10-13,15H2,1-3H3,(H,31,39)/b24-22-,32-23+/t21-,25-,26+,27-,29-/s2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 90n/an/an/an/a8.022



Schering AG



Assay Description
Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.


Chembiochem 6: 531-40 (2005)


Article DOI: 10.1002/cbic.200400108
BindingDB Entry DOI: 10.7270/Q2B56H8H
More data for this
Ligand-Target Pair