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5 similar compounds to monomer 84468

Wt: 149.1
BDBM84615
Wt: 133.1
BDBM50088627
Wt: 149.1
BDBM50283600
Wt: 163.1
BDBM50035932
Wt: 163.1
BDBM50035933

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 84615,50088627,50283600,50035932,50035933   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Golgi alpha-mannosidase II


(Drosophila melanogaster (Fruit fly))
BDBM84615
PNG
(Mannostatin analogue, 4a)
Show SMILES N[C@@H]1[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2/t1-,2-,3-,4+,5-/m1/s1
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300n/an/an/an/an/an/an/an/a



University of Toronto



Assay Description
The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...


Chembiochem 10: 268-77 (2009)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Golgi alpha-mannosidase II


(Drosophila melanogaster (Fruit fly))
BDBM50088627
PNG
((1S,2S,3R,4R)-4-Amino-cyclopentane-1,2,3-triol | (...)
Show SMILES N[C@@H]1C[C@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C5H11NO3/c6-2-1-3(7)5(9)4(2)8/h2-5,7-9H,1,6H2/t2-,3+,4-,5+/m1/s1
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2.65E+5n/an/an/an/an/an/an/an/a



University of Toronto



Assay Description
The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...


Chembiochem 10: 268-77 (2009)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
alpha-Glucosidase (α-Glucosidase)


(Rattus norvegicus (Rat))
BDBM50035932
PNG
(CHEMBL3358658)
Show SMILES N[C@H]1C[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1/C6H13NO4/c7-2-1-3(8)5(10)6(11)4(2)9/h2-6,8-11H,1,7H2/t2-,3+,4-,5-,6-/s2
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PubMed
n/an/a 7.30E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose substrate incubated for 10 mins


Bioorg Med Chem Lett 24: 5530-3 (2014)

More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Rattus norvegicus (Rat))
BDBM50035933
PNG
(CHEMBL3358659)
Show SMILES N[C@@H]1C[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1/C6H13NO4/c7-2-1-3(8)5(10)6(11)4(2)9/h2-6,8-11H,1,7H2/t2-,3-,4+,5+,6+/s2
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n/an/a 6.80E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose substrate incubated for 10 mins


Bioorg Med Chem Lett 24: 5530-3 (2014)

More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a 4.69E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Bioorg Med Chem Lett 4: 2643-2648 (1994)

More data for this
Ligand-Target Pair
Beta-glucocerebrosidase


(Homo sapiens (human))
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a 8.38E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL




Bioorg Med Chem Lett 4: 2643-2648 (1994)

More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a 2.41E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Bioorg Med Chem Lett 4: 2643-2648 (1994)

More data for this
Ligand-Target Pair
Beta-glucocerebrosidase


(Homo sapiens (human))
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a>3.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity was determined against almonds beta-glucosidase


Bioorg Med Chem Lett 4: 2643-2648 (1994)

More data for this
Ligand-Target Pair
Beta-glucocerebrosidase


(Homo sapiens (human))
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a 1.29E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL




Bioorg Med Chem Lett 4: 2643-2648 (1994)

More data for this
Ligand-Target Pair
Alpha glucosidase


(Homo sapiens)
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a>3.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL




Bioorg Med Chem Lett 4: 2643-2648 (1994)

More data for this
Ligand-Target Pair
Alpha glucosidase


(Homo sapiens)
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a>3.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL




Bioorg Med Chem Lett 4: 2643-2648 (1994)

More data for this
Ligand-Target Pair
Beta-glucocerebrosidase


(Homo sapiens (human))
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a>3.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL




Bioorg Med Chem Lett 4: 2643-2648 (1994)

More data for this
Ligand-Target Pair
Beta-glucocerebrosidase


(Homo sapiens (human))
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a 1.17E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL




Bioorg Med Chem Lett 4: 2643-2648 (1994)

More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Homo sapiens)
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a>3.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity was determined against Escherichia coli Alpha-galactosidase


Bioorg Med Chem Lett 4: 2643-2648 (1994)

More data for this
Ligand-Target Pair
Glucocerebrosidase (Acid beta-Glucosidase)


(Homo sapiens (human))
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a 7.78E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity was determined against Escherichia coli beta galactosidase


Bioorg Med Chem Lett 4: 2643-2648 (1994)

More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a>3.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity was determined against Escherichia coli Alpha-galactosidase


Bioorg Med Chem Lett 4: 2643-2648 (1994)

More data for this
Ligand-Target Pair