BindingDB logo
myBDB logout

13 similar compounds to monomer 50244033

Compile data set for download or QSAR
Wt: 390.4
BDBM85039
Purchase
Wt: 390.4
BDBM85040
Wt: 314.3
BDBM50007552
Wt: 390.4
BDBM50007553
Wt: 342.3
BDBM50007554
Wt: 300.3
BDBM50010629
Wt: 426.5
BDBM50065228
Wt: 412.5
BDBM50065233
Wt: 440.4
BDBM50065234
Wt: 404.4
BDBM50065238
Wt: 424.4
BDBM50065239
Wt: 356.4
BDBM50065243
Wt: 440.4
BDBM50083885

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 87 hits for monomerid = 85039,85040,50007552,50007553,50007554,50010629,50065228,50065233,50065234,50065238,50065239,50065243,50083885   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50007552
PNG
(6-Methoxy-4-methoxymethyl-9H-beta-carboline-3-carb...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OC)cc3c2c1COC
Show InChI InChI=1S/C17H18N2O4/c1-4-23-17(20)16-12(9-21-2)15-11-7-10(22-3)5-6-13(11)19-14(15)8-18-16/h5-8,18H,4,9H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
0.140n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50007552
PNG
(6-Methoxy-4-methoxymethyl-9H-beta-carboline-3-carb...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OC)cc3c2c1COC
Show InChI InChI=1S/C17H18N2O4/c1-4-23-17(20)16-12(9-21-2)15-11-7-10(22-3)5-6-13(11)19-14(15)8-18-16/h5-8,18H,4,9H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
0.140n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha1-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50007554
PNG
(4-Methoxymethyl-6-propoxy-9H-beta-carboline-3-carb...)
Show SMILES CCCOc1ccc2[nH]c3cnc(C(=O)OCC)c(COC)c3c2c1
Show InChI InChI=1S/C19H22N2O4/c1-4-8-25-12-6-7-15-13(9-12)17-14(11-23-3)18(19(22)24-5-2)20-10-16(17)21-15/h6-7,9-10,21H,4-5,8,11H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.490n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha1-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50007554
PNG
(4-Methoxymethyl-6-propoxy-9H-beta-carboline-3-carb...)
Show SMILES CCCOc1ccc2[nH]c3cnc(C(=O)OCC)c(COC)c3c2c1
Show InChI InChI=1S/C19H22N2O4/c1-4-8-25-12-6-7-15-13(9-12)17-14(11-23-3)18(19(22)24-5-2)20-10-16(17)21-15/h6-7,9-10,21H,4-5,8,11H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.490n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50007552
PNG
(6-Methoxy-4-methoxymethyl-9H-beta-carboline-3-carb...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OC)cc3c2c1COC
Show InChI InChI=1S/C17H18N2O4/c1-4-23-17(20)16-12(9-21-2)15-11-7-10(22-3)5-6-13(11)19-14(15)8-18-16/h5-8,18H,4,9H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
1.19n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha2-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50007552
PNG
(6-Methoxy-4-methoxymethyl-9H-beta-carboline-3-carb...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OC)cc3c2c1COC
Show InChI InChI=1S/C17H18N2O4/c1-4-23-17(20)16-12(9-21-2)15-11-7-10(22-3)5-6-13(11)19-14(15)8-18-16/h5-8,18H,4,9H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
1.20n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-2-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50007554
PNG
(4-Methoxymethyl-6-propoxy-9H-beta-carboline-3-carb...)
Show SMILES CCCOc1ccc2[nH]c3cnc(C(=O)OCC)c(COC)c3c2c1
Show InChI InChI=1S/C19H22N2O4/c1-4-8-25-12-6-7-15-13(9-12)17-14(11-23-3)18(19(22)24-5-2)20-10-16(17)21-15/h6-7,9-10,21H,4-5,8,11H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.20n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-2-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50007554
PNG
(4-Methoxymethyl-6-propoxy-9H-beta-carboline-3-carb...)
Show SMILES CCCOc1ccc2[nH]c3cnc(C(=O)OCC)c(COC)c3c2c1
Show InChI InChI=1S/C19H22N2O4/c1-4-8-25-12-6-7-15-13(9-12)17-14(11-23-3)18(19(22)24-5-2)20-10-16(17)21-15/h6-7,9-10,21H,4-5,8,11H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.21n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha2-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens-HUMAN)
BDBM50007552
PNG
(6-Methoxy-4-methoxymethyl-9H-beta-carboline-3-carb...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OC)cc3c2c1COC
Show InChI InChI=1S/C17H18N2O4/c1-4-23-17(20)16-12(9-21-2)15-11-7-10(22-3)5-6-13(11)19-14(15)8-18-16/h5-8,18H,4,9H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
1.70n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens-HUMAN)
BDBM50007552
PNG
(6-Methoxy-4-methoxymethyl-9H-beta-carboline-3-carb...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OC)cc3c2c1COC
Show InChI InChI=1S/C17H18N2O4/c1-4-23-17(20)16-12(9-21-2)15-11-7-10(22-3)5-6-13(11)19-14(15)8-18-16/h5-8,18H,4,9H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
1.70n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha3-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50010629
PNG
(6-Hydroxy-4-methoxymethyl-9H-beta-carboline-3-carb...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(O)cc3c2c1COC
Show InChI InChI=1S/C16H16N2O4/c1-3-22-16(20)15-11(8-21-2)14-10-6-9(19)4-5-12(10)18-13(14)7-17-15/h4-7,17,19H,3,8H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
2n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens-HUMAN)
BDBM50007554
PNG
(4-Methoxymethyl-6-propoxy-9H-beta-carboline-3-carb...)
Show SMILES CCCOc1ccc2[nH]c3cnc(C(=O)OCC)c(COC)c3c2c1
Show InChI InChI=1S/C19H22N2O4/c1-4-8-25-12-6-7-15-13(9-12)17-14(11-23-3)18(19(22)24-5-2)20-10-16(17)21-15/h6-7,9-10,21H,4-5,8,11H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.20n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha3-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens-HUMAN)
BDBM50007554
PNG
(4-Methoxymethyl-6-propoxy-9H-beta-carboline-3-carb...)
Show SMILES CCCOc1ccc2[nH]c3cnc(C(=O)OCC)c(COC)c3c2c1
Show InChI InChI=1S/C19H22N2O4/c1-4-8-25-12-6-7-15-13(9-12)17-14(11-23-3)18(19(22)24-5-2)20-10-16(17)21-15/h6-7,9-10,21H,4-5,8,11H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.20n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50007554
PNG
(4-Methoxymethyl-6-propoxy-9H-beta-carboline-3-carb...)
Show SMILES CCCOc1ccc2[nH]c3cnc(C(=O)OCC)c(COC)c3c2c1
Show InChI InChI=1S/C19H22N2O4/c1-4-8-25-12-6-7-15-13(9-12)17-14(11-23-3)18(19(22)24-5-2)20-10-16(17)21-15/h6-7,9-10,21H,4-5,8,11H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.40n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50007554
PNG
(4-Methoxymethyl-6-propoxy-9H-beta-carboline-3-carb...)
Show SMILES CCCOc1ccc2[nH]c3cnc(C(=O)OCC)c(COC)c3c2c1
Show InChI InChI=1S/C19H22N2O4/c1-4-8-25-12-6-7-15-13(9-12)17-14(11-23-3)18(19(22)24-5-2)20-10-16(17)21-15/h6-7,9-10,21H,4-5,8,11H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.40n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50007552
PNG
(6-Methoxy-4-methoxymethyl-9H-beta-carboline-3-carb...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OC)cc3c2c1COC
Show InChI InChI=1S/C17H18N2O4/c1-4-23-17(20)16-12(9-21-2)15-11-7-10(22-3)5-6-13(11)19-14(15)8-18-16/h5-8,18H,4,9H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
4n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50007552
PNG
(6-Methoxy-4-methoxymethyl-9H-beta-carboline-3-carb...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OC)cc3c2c1COC
Show InChI InChI=1S/C17H18N2O4/c1-4-23-17(20)16-12(9-21-2)15-11-7-10(22-3)5-6-13(11)19-14(15)8-18-16/h5-8,18H,4,9H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
4n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50007553
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4ccccc4)cc3c2c1COC
Show InChI InChI=1S/C23H22N2O4/c1-3-28-23(26)22-18(14-27-2)21-17-11-16(29-13-15-7-5-4-6-8-15)9-10-19(17)25-20(21)12-24-22/h4-12,24H,3,13-14H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
4.10n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha1-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50007553
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4ccccc4)cc3c2c1COC
Show InChI InChI=1S/C23H22N2O4/c1-3-28-23(26)22-18(14-27-2)21-17-11-16(29-13-15-7-5-4-6-8-15)9-10-19(17)25-20(21)12-24-22/h4-12,24H,3,13-14H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
4.10n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50007553
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4ccccc4)cc3c2c1COC
Show InChI InChI=1S/C23H22N2O4/c1-3-28-23(26)22-18(14-27-2)21-17-11-16(29-13-15-7-5-4-6-8-15)9-10-19(17)25-20(21)12-24-22/h4-12,24H,3,13-14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
4.20n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha2-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50007553
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4ccccc4)cc3c2c1COC
Show InChI InChI=1S/C23H22N2O4/c1-3-28-23(26)22-18(14-27-2)21-17-11-16(29-13-15-7-5-4-6-8-15)9-10-19(17)25-20(21)12-24-22/h4-12,24H,3,13-14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
4.20n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-2-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50007553
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4ccccc4)cc3c2c1COC
Show InChI InChI=1S/C23H22N2O4/c1-3-28-23(26)22-18(14-27-2)21-17-11-16(29-13-15-7-5-4-6-8-15)9-10-19(17)25-20(21)12-24-22/h4-12,24H,3,13-14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
4.5n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50007553
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4ccccc4)cc3c2c1COC
Show InChI InChI=1S/C23H22N2O4/c1-3-28-23(26)22-18(14-27-2)21-17-11-16(29-13-15-7-5-4-6-8-15)9-10-19(17)25-20(21)12-24-22/h4-12,24H,3,13-14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
4.5n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50010629
PNG
(6-Hydroxy-4-methoxymethyl-9H-beta-carboline-3-carb...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(O)cc3c2c1COC
Show InChI InChI=1S/C16H16N2O4/c1-3-22-16(20)15-11(8-21-2)14-10-6-9(19)4-5-12(10)18-13(14)7-17-15/h4-7,17,19H,3,8H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
5.40n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-2-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens-HUMAN)
BDBM50007553
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4ccccc4)cc3c2c1COC
Show InChI InChI=1S/C23H22N2O4/c1-3-28-23(26)22-18(14-27-2)21-17-11-16(29-13-15-7-5-4-6-8-15)9-10-19(17)25-20(21)12-24-22/h4-12,24H,3,13-14H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
6n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha3-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50065238
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES COCc1c([nH]cc2nc3ccc(OCc4ccccc4)cc3c12)C(=O)OC(C)C
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-24(27)23-19(14-28-3)22-18-11-17(29-13-16-7-5-4-6-8-16)9-10-20(18)26-21(22)12-25-23/h4-12,15,25H,13-14H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
6n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50065238
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES COCc1c([nH]cc2nc3ccc(OCc4ccccc4)cc3c12)C(=O)OC(C)C
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-24(27)23-19(14-28-3)22-18-11-17(29-13-16-7-5-4-6-8-16)9-10-20(18)26-21(22)12-25-23/h4-12,15,25H,13-14H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
6n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens-HUMAN)
BDBM50007553
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4ccccc4)cc3c2c1COC
Show InChI InChI=1S/C23H22N2O4/c1-3-28-23(26)22-18(14-27-2)21-17-11-16(29-13-15-7-5-4-6-8-15)9-10-19(17)25-20(21)12-24-22/h4-12,24H,3,13-14H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
6n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens-HUMAN)
BDBM50065238
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES COCc1c([nH]cc2nc3ccc(OCc4ccccc4)cc3c12)C(=O)OC(C)C
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-24(27)23-19(14-28-3)22-18-11-17(29-13-16-7-5-4-6-8-16)9-10-20(18)26-21(22)12-25-23/h4-12,15,25H,13-14H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
7.5n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens-HUMAN)
BDBM50065238
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES COCc1c([nH]cc2nc3ccc(OCc4ccccc4)cc3c12)C(=O)OC(C)C
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-24(27)23-19(14-28-3)22-18-11-17(29-13-16-7-5-4-6-8-16)9-10-20(18)26-21(22)12-25-23/h4-12,15,25H,13-14H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
7.5n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha3-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens-HUMAN)
BDBM50010629
PNG
(6-Hydroxy-4-methoxymethyl-9H-beta-carboline-3-carb...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(O)cc3c2c1COC
Show InChI InChI=1S/C16H16N2O4/c1-3-22-16(20)15-11(8-21-2)14-10-6-9(19)4-5-12(10)18-13(14)7-17-15/h4-7,17,19H,3,8H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
11n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50065238
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES COCc1c([nH]cc2nc3ccc(OCc4ccccc4)cc3c12)C(=O)OC(C)C
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-24(27)23-19(14-28-3)22-18-11-17(29-13-16-7-5-4-6-8-16)9-10-20(18)26-21(22)12-25-23/h4-12,15,25H,13-14H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
12n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50065238
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES COCc1c([nH]cc2nc3ccc(OCc4ccccc4)cc3c12)C(=O)OC(C)C
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-24(27)23-19(14-28-3)22-18-11-17(29-13-16-7-5-4-6-8-16)9-10-20(18)26-21(22)12-25-23/h4-12,15,25H,13-14H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
12.4n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha1-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50083885
PNG
(4-Methoxymethyl-6-(naphthalen-2-ylmethoxy)-9H-beta...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4ccc5ccccc5c4)cc3c2c1COC
Show InChI InChI=1S/C27H24N2O4/c1-3-32-27(30)26-22(16-31-2)25-21-13-20(10-11-23(21)29-24(25)14-28-26)33-15-17-8-9-18-6-4-5-7-19(18)12-17/h4-14,28H,3,15-16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
15n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50065238
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES COCc1c([nH]cc2nc3ccc(OCc4ccccc4)cc3c12)C(=O)OC(C)C
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-24(27)23-19(14-28-3)22-18-11-17(29-13-16-7-5-4-6-8-16)9-10-20(18)26-21(22)12-25-23/h4-12,15,25H,13-14H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
15n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-2-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50065238
PNG
(6-Benzyloxy-4-methoxymethyl-9H-beta-carboline-3-ca...)
Show SMILES COCc1c([nH]cc2nc3ccc(OCc4ccccc4)cc3c12)C(=O)OC(C)C
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-24(27)23-19(14-28-3)22-18-11-17(29-13-16-7-5-4-6-8-16)9-10-20(18)26-21(22)12-25-23/h4-12,15,25H,13-14H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
15.3n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha2-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50065234
PNG
(4-Methoxymethyl-6-(naphthalen-1-ylmethoxy)-9H-beta...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4cccc5ccccc45)cc3c2c1COC
Show InChI InChI=1S/C27H24N2O4/c1-3-32-27(30)26-22(16-31-2)25-21-13-19(11-12-23(21)29-24(25)14-28-26)33-15-18-9-6-8-17-7-4-5-10-20(17)18/h4-14,28H,3,15-16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
15.4n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha1-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50010629
PNG
(6-Hydroxy-4-methoxymethyl-9H-beta-carboline-3-carb...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(O)cc3c2c1COC
Show InChI InChI=1S/C16H16N2O4/c1-3-22-16(20)15-11(8-21-2)14-10-6-9(19)4-5-12(10)18-13(14)7-17-15/h4-7,17,19H,3,8H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
19n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50065243
PNG
(4-Methoxymethyl-9-methyl-6-propoxy-9H-beta-carboli...)
Show SMILES CCCOc1ccc2n(C)c3cnc(C(=O)OCC)c(COC)c3c2c1
Show InChI InChI=1S/C20H24N2O4/c1-5-9-26-13-7-8-16-14(10-13)18-15(12-24-4)19(20(23)25-6-2)21-11-17(18)22(16)3/h7-8,10-11H,5-6,9,12H2,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
26n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50065243
PNG
(4-Methoxymethyl-9-methyl-6-propoxy-9H-beta-carboli...)
Show SMILES CCCOc1ccc2n(C)c3cnc(C(=O)OCC)c(COC)c3c2c1
Show InChI InChI=1S/C20H24N2O4/c1-5-9-26-13-7-8-16-14(10-13)18-15(12-24-4)19(20(23)25-6-2)21-11-17(18)22(16)3/h7-8,10-11H,5-6,9,12H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
105n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-2-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50065243
PNG
(4-Methoxymethyl-9-methyl-6-propoxy-9H-beta-carboli...)
Show SMILES CCCOc1ccc2n(C)c3cnc(C(=O)OCC)c(COC)c3c2c1
Show InChI InChI=1S/C20H24N2O4/c1-5-9-26-13-7-8-16-14(10-13)18-15(12-24-4)19(20(23)25-6-2)21-11-17(18)22(16)3/h7-8,10-11H,5-6,9,12H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
161n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens-HUMAN)
BDBM50065243
PNG
(4-Methoxymethyl-9-methyl-6-propoxy-9H-beta-carboli...)
Show SMILES CCCOc1ccc2n(C)c3cnc(C(=O)OCC)c(COC)c3c2c1
Show InChI InChI=1S/C20H24N2O4/c1-5-9-26-13-7-8-16-14(10-13)18-15(12-24-4)19(20(23)25-6-2)21-11-17(18)22(16)3/h7-8,10-11H,5-6,9,12H2,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
164n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50065239
PNG
(4-Ethyl-6-(naphthalen-1-ylmethoxy)-9H-beta-carboli...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4cccc5ccccc45)cc3c2c1CC
Show InChI InChI=1S/C27H24N2O3/c1-3-20-25-22-14-19(32-16-18-10-7-9-17-8-5-6-11-21(17)18)12-13-23(22)29-24(25)15-28-26(20)27(30)31-4-2/h5-15,28H,3-4,16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
183n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha1-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50065239
PNG
(4-Ethyl-6-(naphthalen-1-ylmethoxy)-9H-beta-carboli...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4cccc5ccccc45)cc3c2c1CC
Show InChI InChI=1S/C27H24N2O3/c1-3-20-25-22-14-19(32-16-18-10-7-9-17-8-5-6-11-21(17)18)12-13-23(22)29-24(25)15-28-26(20)27(30)31-4-2/h5-15,28H,3-4,16H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
270n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50065239
PNG
(4-Ethyl-6-(naphthalen-1-ylmethoxy)-9H-beta-carboli...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4cccc5ccccc45)cc3c2c1CC
Show InChI InChI=1S/C27H24N2O3/c1-3-20-25-22-14-19(32-16-18-10-7-9-17-8-5-6-11-21(17)18)12-13-23(22)29-24(25)15-28-26(20)27(30)31-4-2/h5-15,28H,3-4,16H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
291n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha2-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens-HUMAN)
BDBM50065234
PNG
(4-Methoxymethyl-6-(naphthalen-1-ylmethoxy)-9H-beta...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4cccc5ccccc45)cc3c2c1COC
Show InChI InChI=1S/C27H24N2O4/c1-3-32-27(30)26-22(16-31-2)25-21-13-19(11-12-23(21)29-24(25)14-28-26)33-15-18-9-6-8-17-7-4-5-10-20(17)18/h4-14,28H,3,15-16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
293n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha3-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens-HUMAN)
BDBM50083885
PNG
(4-Methoxymethyl-6-(naphthalen-2-ylmethoxy)-9H-beta...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4ccc5ccccc5c4)cc3c2c1COC
Show InChI InChI=1S/C27H24N2O4/c1-3-32-27(30)26-22(16-31-2)25-21-13-20(10-11-23(21)29-24(25)14-28-26)33-15-17-8-9-18-6-4-5-7-19(18)12-17/h4-14,28H,3,15-16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
293n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens-HUMAN)
BDBM50065239
PNG
(4-Ethyl-6-(naphthalen-1-ylmethoxy)-9H-beta-carboli...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4cccc5ccccc45)cc3c2c1CC
Show InChI InChI=1S/C27H24N2O3/c1-3-20-25-22-14-19(32-16-18-10-7-9-17-8-5-6-11-21(17)18)12-13-23(22)29-24(25)15-28-26(20)27(30)31-4-2/h5-15,28H,3-4,16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
300n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing GABA alpha3-beta3-gamma2 receptor


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50083885
PNG
(4-Methoxymethyl-6-(naphthalen-2-ylmethoxy)-9H-beta...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4ccc5ccccc5c4)cc3c2c1COC
Show InChI InChI=1S/C27H24N2O4/c1-3-32-27(30)26-22(16-31-2)25-21-13-20(10-11-23(21)29-24(25)14-28-26)33-15-17-8-9-18-6-4-5-7-19(18)12-17/h4-14,28H,3,15-16H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
323n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2


J Med Chem 43: 71-95 (2000)


Article DOI: 10.1021/jm990341r
BindingDB Entry DOI: 10.7270/Q2W37X0J
More data for this
Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit


(Homo sapiens-Homo sapiens (Human))
BDBM50065234
PNG
(4-Methoxymethyl-6-(naphthalen-1-ylmethoxy)-9H-beta...)
Show SMILES CCOC(=O)c1[nH]cc2nc3ccc(OCc4cccc5ccccc45)cc3c2c1COC
Show InChI InChI=1S/C27H24N2O4/c1-3-32-27(30)26-22(16-31-2)25-21-13-19(11-12-23(21)29-24(25)14-28-26)33-15-18-9-6-8-17-7-4-5-10-20(17)18/h4-14,28H,3,15-16H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
323n/an/an/an/an/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity measured using LtK- cell membranes expressing Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2


J Med Chem 41: 2537-52 (1998)


Article DOI: 10.1021/jm970460b
BindingDB Entry DOI: 10.7270/Q2QN65WP
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 87 total )  |  Next  |  Last  >>