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8 similar compounds to monomer 98618

Compile data set for download or QSAR
Wt: 328.3
BDBM98605
Wt: 354.4
BDBM98606
Wt: 340.3
BDBM98607
Wt: 340.3
BDBM98608
Wt: 420.4
BDBM98610
Wt: 344.3
BDBM98614
Wt: 390.4
BDBM98615
Wt: 358.3
BDBM98617
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 98605,98606,98607,98608,98610,98614,98615,98617   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3


(Homo sapiens (Human))
BDBM98605
PNG
(2-amino-1-ethyl-7-[2-(3-hydroxytetrahydrofuran-3-y...)
Show SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC(C)(C)O
Show InChI InChI=1S/C17H20N4O3/c1-5-21-14(18)12(16(23)19-4)13(22)11-7-6-10(20-15(11)21)8-9-17(2,3)24/h6-7,24H,5,18H2,1-4H3,(H,19,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 23n/an/an/an/an/a20



Sanofi

US Patent


Assay Description
Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.


US Patent US8470847 (2013)


BindingDB Entry DOI: 10.7270/Q2WD3Z67
More data for this
Ligand-Target Pair
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3


(Homo sapiens (Human))
BDBM98606
PNG
(2-amino-7-(3,4-dihydroxy-3-methyl-but-1-ynyl)-1-et...)
Show SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC1(O)CCCC1
Show InChI InChI=1S/C19H22N4O3/c1-3-23-16(20)14(18(25)21-2)15(24)13-7-6-12(22-17(13)23)8-11-19(26)9-4-5-10-19/h6-7,26H,3-5,9-10,20H2,1-2H3,(H,21,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 46n/an/an/an/an/a20



Sanofi

US Patent


Assay Description
Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.


US Patent US8470847 (2013)


BindingDB Entry DOI: 10.7270/Q2WD3Z67
More data for this
Ligand-Target Pair
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3


(Homo sapiens (Human))
BDBM98607
PNG
(2-amino-7-(3-cyclopropyl-3-hydroxy-prop-1-ynyl)-1-...)
Show SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC(O)C1CC1
Show InChI InChI=1S/C18H20N4O3/c1-3-22-16(19)14(18(25)20-2)15(24)12-8-6-11(21-17(12)22)7-9-13(23)10-4-5-10/h6,8,10,13,23H,3-5,19H2,1-2H3,(H,20,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 37n/an/an/an/an/a20



Sanofi

US Patent


Assay Description
Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.


US Patent US8470847 (2013)


BindingDB Entry DOI: 10.7270/Q2WD3Z67
More data for this
Ligand-Target Pair
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3


(Homo sapiens (Human))
BDBM98617
PNG
(2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methyl-bu...)
Show SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC(C)(O)COC
Show InChI InChI=1S/C18H22N4O4/c1-5-22-15(19)13(17(24)20-3)14(23)12-7-6-11(21-16(12)22)8-9-18(2,25)10-26-4/h6-7,25H,5,10,19H2,1-4H3,(H,20,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 23n/an/an/an/an/a20



Sanofi

US Patent


Assay Description
Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.


US Patent US8470847 (2013)


BindingDB Entry DOI: 10.7270/Q2WD3Z67
More data for this
Ligand-Target Pair
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3


(Homo sapiens (Human))
BDBM98610
PNG
(2-amino-1-ethyl-7-[3-hydroxy-3-(3-methoxyphenyl)bu...)
Show SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC(C)(O)c1cccc(OC)c1
Show InChI InChI=1S/C23H24N4O4/c1-5-27-20(24)18(22(29)25-3)19(28)17-10-9-15(26-21(17)27)11-12-23(2,30)14-7-6-8-16(13-14)31-4/h6-10,13,30H,5,24H2,1-4H3,(H,25,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 6n/an/an/an/an/a20



Sanofi

US Patent


Assay Description
Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.


US Patent US8470847 (2013)


BindingDB Entry DOI: 10.7270/Q2WD3Z67
More data for this
Ligand-Target Pair
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3


(Homo sapiens (Human))
BDBM98614
PNG
(2-amino-7-(3,4-dihydroxy-3-methyl-but-1-ynyl)-1-et...)
Show SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC(C)(O)CO
Show InChI InChI=1S/C17H20N4O4/c1-4-21-14(18)12(16(24)19-3)13(23)11-6-5-10(20-15(11)21)7-8-17(2,25)9-22/h5-6,22,25H,4,9,18H2,1-3H3,(H,19,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 43n/an/an/an/an/a20



Sanofi

US Patent


Assay Description
Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.


US Patent US8470847 (2013)


BindingDB Entry DOI: 10.7270/Q2WD3Z67
More data for this
Ligand-Target Pair
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3


(Homo sapiens (Human))
BDBM98615
PNG
(2-amino-1-ethyl-7-(3-hydroxy-3-phenyl-but-1-ynyl)-...)
Show SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC(C)(O)c1ccccc1
Show InChI InChI=1S/C22H22N4O3/c1-4-26-19(23)17(21(28)24-3)18(27)16-11-10-15(25-20(16)26)12-13-22(2,29)14-8-6-5-7-9-14/h5-11,29H,4,23H2,1-3H3,(H,24,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 14n/an/an/an/an/a20



Sanofi

US Patent


Assay Description
Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.


US Patent US8470847 (2013)


BindingDB Entry DOI: 10.7270/Q2WD3Z67
More data for this
Ligand-Target Pair
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3


(Homo sapiens (Human))
BDBM98608
PNG
(2-amino-1-ethyl-7-[2-(1-hydroxycyclobutyl)ethynyl]...)
Show SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC1(O)CCC1
Show InChI InChI=1S/C18H20N4O3/c1-3-22-15(19)13(17(24)20-2)14(23)12-6-5-11(21-16(12)22)7-10-18(25)8-4-9-18/h5-6,25H,3-4,8-9,19H2,1-2H3,(H,20,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 21n/an/an/an/an/a20



Sanofi

US Patent


Assay Description
Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.


US Patent US8470847 (2013)


BindingDB Entry DOI: 10.7270/Q2WD3Z67
More data for this
Ligand-Target Pair