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There are 8 purchasable compounds for target: ATP-PRT

Wt: 295.2
BDBM25324
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Wt: 267.2
BDBM25325
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Wt: 405.4
BDBM25314
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Wt: 446.4
BDBM25316
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Wt: 491.6
BDBM25318
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Wt: 494.9
BDBM25321
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Wt: 424.1
BDBM25322
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Wt: 424.3
BDBM25323
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 25324,25325,25314,25316,25318,25321,25322,25323   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ATP Phosphoribosyltransferase


(Mycobacterium tuberculosis)
BDBM25314
PNG
(2-[(5,6-diphenyl-1,2,4-triazin-3-yl)sulfanyl]-N-(1...)
Show SMILES O=C(CSc1nnc(-c2ccccc2)c(n1)-c1ccccc1)Nc1nccs1
Show InChI InChI=1S/C20H15N5OS2/c26-16(22-19-21-11-12-27-19)13-28-20-23-17(14-7-3-1-4-8-14)18(24-25-20)15-9-5-2-6-10-15/h1-12H,13H2,(H,21,22,26)
PDB
MMDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.00E+3n/an/an/an/a8.522



Yale University



Assay Description
Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...


J Med Chem 51: 5984-92 (2008)

More data for this
Ligand-Target Pair
ATP Phosphoribosyltransferase


(Mycobacterium tuberculosis)
BDBM25316
PNG
(ChemBridge nitrobenzothiazole, 6 | N-(6-nitro-1,3-...)
Show SMILES [O-][N+](=O)c1ccc2nc(NC(=O)CC(NC(=O)c3ccccc3)c3ccccc3)sc2c1
Show InChI InChI=1S/C23H18N4O4S/c28-21(26-23-25-18-12-11-17(27(30)31)13-20(18)32-23)14-19(15-7-3-1-4-8-15)24-22(29)16-9-5-2-6-10-16/h1-13,19H,14H2,(H,24,29)(H,25,26,28)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.00E+3n/an/an/an/a8.522



Yale University



Assay Description
Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...


J Med Chem 51: 5984-92 (2008)

More data for this
Ligand-Target Pair
ATP Phosphoribosyltransferase


(Mycobacterium tuberculosis)
BDBM25318
PNG
((4-methoxyphenyl)methyl 2-methyl-5-oxo-4,7-bis(thi...)
Show SMILES COc1ccc(COC(=O)C2=C(C)N=C3CC(CC(=O)C3C2c2cccs2)c2cccs2)cc1
Show InChI InChI=1S/C27H25NO4S2/c1-16-24(27(30)32-15-17-7-9-19(31-2)10-8-17)26(23-6-4-12-34-23)25-20(28-16)13-18(14-21(25)29)22-5-3-11-33-22/h3-12,18,25-26H,13-15H2,1-2H3
PDB
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PC cid
PC sid
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Article
PubMed
n/an/a 1.00E+4n/an/an/an/a8.522



Yale University



Assay Description
Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...


J Med Chem 51: 5984-92 (2008)

More data for this
Ligand-Target Pair
ATP Phosphoribosyltransferase


(Mycobacterium tuberculosis)
BDBM25325
PNG
(2-[methyl(6-nitro-1,3-benzothiazol-2-yl)amino]acet...)
Show SMILES CN(CC(O)=O)c1nc2ccc(cc2s1)[N+]([O-])=O
Show InChI InChI=1S/C10H9N3O4S/c1-12(5-9(14)15)10-11-7-3-2-6(13(16)17)4-8(7)18-10/h2-4H,5H2,1H3,(H,14,15)
PDB
MMDB

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PC sid
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Article
PubMed
n/an/an/an/an/an/an/a8.522



Yale University



Assay Description
Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...


J Med Chem 51: 5984-92 (2008)

More data for this
Ligand-Target Pair
ATP Phosphoribosyltransferase


(Mycobacterium tuberculosis)
BDBM25322
PNG
(2-bromo-3,5-dinitro-N-[(phenylcarbamoyl)amino]benz...)
Show SMILES [O-][N+](=O)c1cc(C(=O)NNC(=O)Nc2ccccc2)c(Br)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C14H10BrN5O6/c15-12-10(6-9(19(23)24)7-11(12)20(25)26)13(21)17-18-14(22)16-8-4-2-1-3-5-8/h1-7H,(H,17,21)(H2,16,18,22)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.50E+3n/an/an/an/a8.522



Yale University



Assay Description
Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...


J Med Chem 51: 5984-92 (2008)

More data for this
Ligand-Target Pair
ATP Phosphoribosyltransferase


(Mycobacterium tuberculosis)
BDBM25323
PNG
(2-({7-[(3-hydroxyphenyl)amino]-4-nitro-2,1,3-benzo...)
Show SMILES Oc1cccc(Nc2cc(Nc3ccc(cc3O)[N+]([O-])=O)c([N+]([O-])=O)c3nonc23)c1
Show InChI InChI=1S/C18H12N6O7/c25-11-3-1-2-9(6-11)19-13-8-14(18(24(29)30)17-16(13)21-31-22-17)20-12-5-4-10(23(27)28)7-15(12)26/h1-8,19-20,25-26H
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.19E+4n/an/an/an/a8.522



Yale University



Assay Description
Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...


J Med Chem 51: 5984-92 (2008)

More data for this
Ligand-Target Pair
ATP Phosphoribosyltransferase


(Mycobacterium tuberculosis)
BDBM25324
PNG
(ChemBridge nitrobenzothiazole, 19 | ethyl 0-[(6-ni...)
Show SMILES CCOC(=O)C(=O)Nc1nc2ccc(cc2s1)[N+]([O-])=O
Show InChI InChI=1S/C11H9N3O5S/c1-2-19-10(16)9(15)13-11-12-7-4-3-6(14(17)18)5-8(7)20-11/h3-5H,2H2,1H3,(H,12,13,15)
PDB
MMDB

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Article
PubMed
n/an/a 1.39E+4n/an/an/an/a8.522



Yale University



Assay Description
Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...


J Med Chem 51: 5984-92 (2008)

More data for this
Ligand-Target Pair
ATP Phosphoribosyltransferase


(Mycobacterium tuberculosis)
BDBM25321
PNG
((4E)-4-[(4-chlorophenyl)(hydroxy)methylidene]-1-(p...)
Show SMILES COc1cc(cc(OC)c1OC)C1C(C(=O)c2ccc(Cl)cc2)C(=O)C(=O)N1Cc1cccnc1
Show InChI InChI=1S/C26H23ClN2O6/c1-33-19-11-17(12-20(34-2)25(19)35-3)22-21(23(30)16-6-8-18(27)9-7-16)24(31)26(32)29(22)14-15-5-4-10-28-13-15/h4-13,21-22H,14H2,1-3H3
PDB
MMDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a8.522



Yale University



Assay Description
Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...


J Med Chem 51: 5984-92 (2008)

More data for this
Ligand-Target Pair