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There are 7 purchasable compounds for target: alternatively spliced Trp4

Wt: 270.3
BDBM72595
Wt: 226.3
BDBM77617
Purchase
Wt: 228.2
BDBM77619
Purchase
Wt: 299.3
BDBM77614
Purchase
Wt: 319.4
BDBM77615
Purchase
Wt: 214.3
BDBM79618
Purchase
Wt: 258.3
BDBM79629
Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 72595,77617,77619,77614,77615,79618,79629   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
alternatively spliced Trp4


(Mus musculus)
BDBM77614
PNG
((4-Fluoro-benzyl)-[5-(4-fluoro-phenyl)-1-methyl-1H...)
Show SMILES Cn1c(NCc2ccc(F)cc2)ncc1-c1ccc(F)cc1
Show InChI InChI=1S/C17H15F2N3/c1-22-16(13-4-8-15(19)9-5-13)11-21-17(22)20-10-12-2-6-14(18)7-3-12/h2-9,11H,10H2,1H3,(H,20,21)
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PCBioAssay
n/an/a 4.28E+3n/an/an/an/an/an/a



Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay


Assay Description
Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...


Citation and Details
More data for this
Ligand-Target Pair
alternatively spliced Trp4


(Mus musculus)
BDBM77615
PNG
(2-phenyl-N-(2-phenylsulfanylphenyl)acetamide | 2-p...)
Show SMILES O=C(Cc1ccccc1)Nc1ccccc1Sc1ccccc1
Show InChI InChI=1S/C20H17NOS/c22-20(15-16-9-3-1-4-10-16)21-18-13-7-8-14-19(18)23-17-11-5-2-6-12-17/h1-14H,15H2,(H,21,22)
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n/an/a 3.87E+4n/an/an/an/an/an/a



Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay


Assay Description
Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...


Citation and Details
More data for this
Ligand-Target Pair
alternatively spliced Trp4


(Mus musculus)
BDBM72595
PNG
(2-(1-azepanyl)-7-methoxy-4-methylquinoline;oxalic ...)
Show SMILES COc1ccc2c(C)cc(nc2c1)N1CCCCCC1
Show InChI InChI=1S/C17H22N2O/c1-13-11-17(19-9-5-3-4-6-10-19)18-16-12-14(20-2)7-8-15(13)16/h7-8,11-12H,3-6,9-10H2,1-2H3
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UniChem
PCBioAssay
n/an/a 2.38E+3n/an/an/an/an/an/a



Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay


Assay Description
Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...


Citation and Details
More data for this
Ligand-Target Pair
alternatively spliced Trp4


(Mus musculus)
BDBM79629
PNG
(2-(1-azepanyl)-6-fluoro-4-methylquinoline;2,2,2-tr...)
Show SMILES Cc1cc(nc2ccc(F)cc12)N1CCCCCC1
Show InChI InChI=1S/C16H19FN2/c1-12-10-16(19-8-4-2-3-5-9-19)18-15-7-6-13(17)11-14(12)15/h6-7,10-11H,2-5,8-9H2,1H3
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PCBioAssay
n/an/a 1.63E+3n/an/an/an/an/an/a



Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay


Assay Description
The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...


Citation and Details
More data for this
Ligand-Target Pair
alternatively spliced Trp4


(Mus musculus)
BDBM77619
PNG
(4-(4-methyl-2-quinolinyl)morpholine;2,2,2-trifluor...)
Show SMILES Cc1cc(nc2ccccc12)N1CCOCC1
Show InChI InChI=1S/C14H16N2O/c1-11-10-14(16-6-8-17-9-7-16)15-13-5-3-2-4-12(11)13/h2-5,10H,6-9H2,1H3
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n/an/a 1.40E+5n/an/an/an/an/an/a



Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay


Assay Description
Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...


Citation and Details
More data for this
Ligand-Target Pair
alternatively spliced Trp4


(Mus musculus)
BDBM79618
PNG
(N,N-diethyl-4-methyl-2-quinolinamine;2,2,2-trifluo...)
Show SMILES CCN(CC)c1cc(C)c2ccccc2n1
Show InChI InChI=1S/C14H18N2/c1-4-16(5-2)14-10-11(3)12-8-6-7-9-13(12)15-14/h6-10H,4-5H2,1-3H3
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PCBioAssay
n/an/a 7.54E+3n/an/an/an/an/an/a



Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay


Assay Description
The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...


Citation and Details
More data for this
Ligand-Target Pair
alternatively spliced Trp4


(Mus musculus)
BDBM77617
PNG
(4-methyl-2-(1-piperidinyl)quinoline | 4-methyl-2-p...)
Show SMILES Cc1cc(nc2ccccc12)N1CCCCC1
Show InChI InChI=1S/C15H18N2/c1-12-11-15(17-9-5-2-6-10-17)16-14-8-4-3-7-13(12)14/h3-4,7-8,11H,2,5-6,9-10H2,1H3
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PCBioAssay
n/an/a 2.63E+3n/an/an/an/an/an/a



Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay


Assay Description
Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...


Citation and Details
More data for this
Ligand-Target Pair