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There are 23 purchasable compounds for target: adrenergic Beta

Wt: 266.3
BDBM25749
Wt: 211.2
BDBM25392
Wt: 229.3
BDBM25760
Wt: 272.3
BDBM25762
Wt: 249.3
BDBM25764
Wt: 239.3
BDBM25769
Wt: 225.2
BDBM25770
Wt: 277.1
BDBM27958
Wt: 259.3
BDBM60973
Wt: 312.4
BDBM82479
Wt: 193.2
BDBM92678
Wt: 195.2
BDBM92680
Wt: 196.6
BDBM50001915
Wt: 169.1
BDBM50029051
Wt: 209.2
BDBM50169785
Displayed 1 to 15 (of 24 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 25749,25392,25760,25762,25764,25769,25770,27958,60973,82479,92678,92680,50001915,50029051,50169785   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ADRB2


(BOVINE)
BDBM25392
PNG
(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Show SMILES CC(C)NCC(O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3
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110n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Compound was evaluated for beta adrenergic binding affinity towards beta-2 receptor of bovine lung


J Med Chem 35: 1009-18 (1992)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM25392
PNG
(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Show SMILES CC(C)NCC(O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3
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110n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Tested for binding affinity against beta-2 adrenergic receptor in bovine lung using [3H]DHA as radioligand


J Med Chem 36: 3077-86 (1993)

More data for this
Ligand-Target Pair
ADRB2


(HUMAN)
BDBM50001915
PNG
(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)
Show SMILES Clc1cccc(c1)N1CCNCC1
Show InChI InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2
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PubMed
2.50E+3n/an/an/an/an/an/an/an/a



Stanford University

Curated by PDSP Ki Database




Biol Psychiatry 25: 569-75 (1989)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM50029051
PNG
((-)-arterenol | (-)-noradrenaline | (-)-norepineph...)
Show SMILES NC[C@H](O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1
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6.00E+3n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Compound was evaluated for beta adrenergic binding affinity towards beta-2 receptor of bovine lung


J Med Chem 35: 1009-18 (1992)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM50029051
PNG
((-)-arterenol | (-)-noradrenaline | (-)-norepineph...)
Show SMILES NC[C@H](O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1
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6.00E+3n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Tested for binding affinity against beta-2 adrenergic receptor in bovine lung using [3H]DHA as radioligand


J Med Chem 36: 3077-86 (1993)

More data for this
Ligand-Target Pair
ADRB2


(HUMAN)
BDBM82479
PNG
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE)
Show SMILES CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1
Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3
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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM92678
PNG
(2-(tert-butylamino)-1-phenylethan-1-ol, 4)
Show SMILES CC(C)(C)NCC(O)c1ccccc1
Show InChI InChI=1S/C12H19NO/c1-12(2,3)13-9-11(14)10-7-5-4-6-8-10/h4-8,11,13-14H,9H2,1-3H3
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n/an/an/a 2.94E+3n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Apparent binding affinity constant to beta-2 adrenergic receptor determined using [3H]DHA


J Med Chem 29: 549-54 (1986)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM27958
PNG
(1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...)
Show SMILES CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1
Show InChI InChI=1S/C12H18Cl2N2O/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7/h4-5,10,16-17H,6,15H2,1-3H3
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n/an/an/a 37n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Apparent binding affinity constant to beta-2 adrenergic receptor determined using [3H]DHA


J Med Chem 29: 549-54 (1986)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM50169785
PNG
((2-Hydroxy-3-phenoxy-propyl)-isopropyl-ammonium | ...)
Show SMILES CC(C)NCC(O)COc1ccccc1
Show InChI InChI=1S/C12H19NO2/c1-10(2)13-8-11(14)9-15-12-6-4-3-5-7-12/h3-7,10-11,13-14H,8-9H2,1-2H3
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n/an/an/a 5.37E+4n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)


J Med Chem 28: 1328-34 (1985)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM25749
PNG
(CHEMBL6995 | N-{4-[2-hydroxy-3-(propan-2-ylamino)p...)
Show SMILES CC(C)NCC(O)COc1ccc(NC(C)=O)cc1
Show InChI InChI=1S/C14H22N2O3/c1-10(2)15-8-13(18)9-19-14-6-4-12(5-7-14)16-11(3)17/h4-7,10,13,15,18H,8-9H2,1-3H3,(H,16,17)
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n/an/an/a 2.04E+4n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)


J Med Chem 28: 1328-34 (1985)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM60973
PNG
((2R)-1-(1-naphthalenyloxy)-3-(propan-2-ylamino)-2-...)
Show SMILES CC(C)NC[C@@H](O)COc1cccc2ccccc12
Show InChI InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3/t14-/m1/s1
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n/an/an/a 0.890n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)


J Med Chem 28: 1328-34 (1985)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM27958
PNG
(1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...)
Show SMILES CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1
Show InChI InChI=1S/C12H18Cl2N2O/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7/h4-5,10,16-17H,6,15H2,1-3H3
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n/an/an/a 36n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)


J Med Chem 28: 1328-34 (1985)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM25769
PNG
(4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxym...)
Show SMILES CC(C)(C)NCC(O)c1ccc(O)c(CO)c1
Show InChI InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3
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n/an/an/a 520n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)


J Med Chem 28: 1328-34 (1985)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM25760
PNG
(1-(naphthalen-2-yl)-2-(propan-2-ylamino)ethan-1-ol...)
Show SMILES CC(C)NCC(O)c1ccc2ccccc2c1
Show InChI InChI=1S/C15H19NO/c1-11(2)16-10-15(17)14-8-7-12-5-3-4-6-13(12)9-14/h3-9,11,15-17H,10H2,1-2H3
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n/an/an/a 160n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)


J Med Chem 28: 1328-34 (1985)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM25770
PNG
(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Show SMILES CC(C)(C)NCC(O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C12H19NO3/c1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8/h4-6,11,13-16H,7H2,1-3H3
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n/an/an/a 3.98E+3n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)


J Med Chem 28: 1328-34 (1985)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM92680
PNG
(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenol, 8)
Show SMILES CC(C)NCC(O)c1ccc(O)cc1
Show InChI InChI=1S/C11H17NO2/c1-8(2)12-7-11(14)9-3-5-10(13)6-4-9/h3-6,8,11-14H,7H2,1-2H3
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n/an/an/a 4.27E+3n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)


J Med Chem 28: 1328-34 (1985)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM25392
PNG
(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Show SMILES CC(C)NCC(O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3
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n/an/an/a 330n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)


J Med Chem 28: 1328-34 (1985)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM25762
PNG
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Show SMILES CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1
Show InChI InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3
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n/an/an/a 580n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)


J Med Chem 28: 1328-34 (1985)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM25770
PNG
(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Show SMILES CC(C)(C)NCC(O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C12H19NO3/c1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8/h4-6,11,13-16H,7H2,1-3H3
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n/an/an/a 4.48E+3n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Apparent binding affinity constant to beta-2 adrenergic receptor determined using [3H]DHA


J Med Chem 29: 549-54 (1986)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM25769
PNG
(4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxym...)
Show SMILES CC(C)(C)NCC(O)c1ccc(O)c(CO)c1
Show InChI InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3
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n/an/an/a 570n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Apparent binding affinity constant to beta-2 adrenergic receptor determined using [3H]DHA


J Med Chem 29: 549-54 (1986)

More data for this
Ligand-Target Pair
ADRB2


(BOVINE)
BDBM25764
PNG
(ALPRENOLOL,(+) | ALPRENOLOL,(-) | Alfeprol | Alphe...)
Show SMILES CC(C)NCC(O)COc1ccccc1CC=C
Show InChI InChI=1S/C15H23NO2/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3
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n/an/a 2.98n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of [3H]dihydroalprenolol radioligand binding to Beta-2 adrenergic receptor in calf lung membranes.


J Med Chem 25: 931-6 (1982)

More data for this
Ligand-Target Pair