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There are 11 purchasable compounds for target: Alpha-tubulin

Wt: 339.3
BDBM81747
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Wt: 374.4
BDBM81748
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Wt: 378.5
BDBM81749
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Wt: 297.3
BDBM81750
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Wt: 358.3
BDBM81751
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Wt: 388.4
BDBM81752
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Wt: 364.4
BDBM81753
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Wt: 381.4
BDBM81755
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Wt: 339.3
BDBM81756
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Wt: 346.8
BDBM81757
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Wt: 348.3
BDBM81758
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 81747,81748,81749,81750,81751,81752,81753,81755,81756,81757,81758   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tubulin


(Leishmania tarentolae (Sauroleishmania tarentolae))
BDBM81758
PNG
(Chembridge No 9044486, Class 4, 6)
Show SMILES COC(=O)c1ccsc1NC(=O)CSc1nc2ccccc2o1
Show InChI InChI=1S/C15H12N2O4S2/c1-20-14(19)9-6-7-22-13(9)17-12(18)8-23-15-16-10-4-2-3-5-11(10)21-15/h2-7H,8H2,1H3,(H,17,18)
PDB

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PubMed
n/an/a 8.10E+4n/an/an/an/an/an/a



The Ohio State University



Assay Description
In vitro activity assay using leishmania tarentolae and porcine brain tubulin.


Chem Biol Drug Des 72: 513-24 (2008)

More data for this
Ligand-Target Pair
Tubulin


(Leishmania tarentolae (Sauroleishmania tarentolae))
BDBM81756
PNG
(Chembridge No 9056942, Class 3, 7)
Show SMILES COc1cc(OC)cc(c1)C(=O)NCc1nc(no1)-c1ccccc1
Show InChI InChI=1S/C18H17N3O4/c1-23-14-8-13(9-15(10-14)24-2)18(22)19-11-16-20-17(21-25-16)12-6-4-3-5-7-12/h3-10H,11H2,1-2H3,(H,19,22)
PDB

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PubMed
n/an/a 7.80E+4n/an/an/an/an/an/a



The Ohio State University



Assay Description
In vitro activity assay using leishmania tarentolae and porcine brain tubulin.


Chem Biol Drug Des 72: 513-24 (2008)

More data for this
Ligand-Target Pair
Tubulin


(Leishmania tarentolae (Sauroleishmania tarentolae))
BDBM81747
PNG
(Chembridge No 9067250, Class 1, 8)
Show SMILES COC(=O)c1ccccc1NS(=O)(=O)c1ccc(OC)c(F)c1
Show InChI InChI=1S/C15H14FNO5S/c1-21-14-8-7-10(9-12(14)16)23(19,20)17-13-6-4-3-5-11(13)15(18)22-2/h3-9,17H,1-2H3
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UniChem
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PubMed
n/an/a 5.50E+4n/an/an/an/an/an/a



The Ohio State University



Assay Description
In vitro activity assay using leishmania tarentolae and porcine brain tubulin.


Chem Biol Drug Des 72: 513-24 (2008)

More data for this
Ligand-Target Pair
Tubulin


(Leishmania tarentolae (Sauroleishmania tarentolae))
BDBM81748
PNG
(Chembridge No 7946770, Class 1, 9)
Show SMILES CCOc1cccc(c1)C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCCC1
Show InChI InChI=1S/C19H22N2O4S/c1-2-25-17-7-5-6-15(14-17)19(22)20-16-8-10-18(11-9-16)26(23,24)21-12-3-4-13-21/h5-11,14H,2-4,12-13H2,1H3,(H,20,22)
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PubMed
n/an/a 5.80E+4n/an/an/an/an/an/a



The Ohio State University



Assay Description
In vitro activity assay using leishmania tarentolae and porcine brain tubulin.


Chem Biol Drug Des 72: 513-24 (2008)

More data for this
Ligand-Target Pair
Tubulin


(Leishmania tarentolae (Sauroleishmania tarentolae))
BDBM81749
PNG
(Chembridge No 7960631, Class 1, 10)
Show SMILES CCN(CC)S(=O)(=O)c1ccc(NC(=O)c2ccccc2SC)cc1
Show InChI InChI=1S/C18H22N2O3S2/c1-4-20(5-2)25(22,23)15-12-10-14(11-13-15)19-18(21)16-8-6-7-9-17(16)24-3/h6-13H,4-5H2,1-3H3,(H,19,21)
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PubMed
n/an/a 6.40E+4n/an/an/an/an/an/a



The Ohio State University



Assay Description
In vitro activity assay using leishmania tarentolae and porcine brain tubulin.


Chem Biol Drug Des 72: 513-24 (2008)

More data for this
Ligand-Target Pair
Tubulin


(Leishmania tarentolae (Sauroleishmania tarentolae))
BDBM81750
PNG
(Chembridge No 9063043, Class 1, 17)
Show SMILES COc1ccccc1NC(=O)c1ccc(OCC(C)=C)cc1
Show InChI InChI=1S/C18H19NO3/c1-13(2)12-22-15-10-8-14(9-11-15)18(20)19-16-6-4-5-7-17(16)21-3/h4-11H,1,12H2,2-3H3,(H,19,20)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.00E+4n/an/an/an/an/an/a



The Ohio State University



Assay Description
In vitro activity assay using leishmania tarentolae and porcine brain tubulin.


Chem Biol Drug Des 72: 513-24 (2008)

More data for this
Ligand-Target Pair
Tubulin


(Leishmania tarentolae (Sauroleishmania tarentolae))
BDBM81752
PNG
(Chembridge No 9035650, Class 2, 12)
Show SMILES COc1ccc(cc1)C(=O)N1CCN(CC1)c1oc(nc1C#N)-c1ccccc1
Show InChI InChI=1S/C22H20N4O3/c1-28-18-9-7-17(8-10-18)21(27)25-11-13-26(14-12-25)22-19(15-23)24-20(29-22)16-5-3-2-4-6-16/h2-10H,11-14H2,1H3
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PubMed
n/an/a 6.60E+4n/an/an/an/an/an/a



The Ohio State University



Assay Description
In vitro activity assay using leishmania tarentolae and porcine brain tubulin.


Chem Biol Drug Des 72: 513-24 (2008)

More data for this
Ligand-Target Pair
Tubulin


(Leishmania tarentolae (Sauroleishmania tarentolae))
BDBM81753
PNG
(Chembridge No 9035165, Class 2, 13)
Show SMILES O=C(N1CCN(CC1)c1oc(nc1C#N)-c1ccccc1)c1cccs1
Show InChI InChI=1S/C19H16N4O2S/c20-13-15-19(25-17(21-15)14-5-2-1-3-6-14)23-10-8-22(9-11-23)18(24)16-7-4-12-26-16/h1-7,12H,8-11H2
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PubMed
n/an/a 6.00E+4n/an/an/an/an/an/a



The Ohio State University



Assay Description
In vitro activity assay using leishmania tarentolae and porcine brain tubulin.


Chem Biol Drug Des 72: 513-24 (2008)

More data for this
Ligand-Target Pair
Tubulin


(Leishmania tarentolae (Sauroleishmania tarentolae))
BDBM81755
PNG
(Chembridge No 9026860, Class 3, 14)
Show SMILES COc1ccc(cc1)C(=O)N(Cc1nc(no1)-c1ccc(OC)cc1)C(C)C
Show InChI InChI=1S/C21H23N3O4/c1-14(2)24(21(25)16-7-11-18(27-4)12-8-16)13-19-22-20(23-28-19)15-5-9-17(26-3)10-6-15/h5-12,14H,13H2,1-4H3
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PubMed
n/an/a 8.90E+4n/an/an/an/an/an/a



The Ohio State University



Assay Description
In vitro activity assay using leishmania tarentolae and porcine brain tubulin.


Chem Biol Drug Des 72: 513-24 (2008)

More data for this
Ligand-Target Pair
Tubulin


(Leishmania tarentolae (Sauroleishmania tarentolae))
BDBM81757
PNG
(Chembridge No 9049411, Class 4, 15)
Show SMILES COc1cc(NC(=O)CSC2=NCCS2)c(OC)cc1Cl
Show InChI InChI=1S/C13H15ClN2O3S2/c1-18-10-6-9(11(19-2)5-8(10)14)16-12(17)7-21-13-15-3-4-20-13/h5-6H,3-4,7H2,1-2H3,(H,16,17)
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PubMed
n/an/a 1.07E+5n/an/an/an/an/an/a



The Ohio State University



Assay Description
In vitro activity assay using leishmania tarentolae and porcine brain tubulin.


Chem Biol Drug Des 72: 513-24 (2008)

More data for this
Ligand-Target Pair
Tubulin


(Leishmania tarentolae (Sauroleishmania tarentolae))
BDBM81751
PNG
(Chembridge No 9041709, Class 2, 11)
Show SMILES O=C(N1CCN(CC1)c1oc(nc1C#N)-c1ccccc1)c1ccccc1
Show InChI InChI=1S/C21H18N4O2/c22-15-18-21(27-19(23-18)16-7-3-1-4-8-16)25-13-11-24(12-14-25)20(26)17-9-5-2-6-10-17/h1-10H,11-14H2
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PubMed
n/an/a 6.80E+4n/an/an/an/an/an/a



The Ohio State University



Assay Description
In vitro activity assay using leishmania tarentolae and porcine brain tubulin.


Chem Biol Drug Des 72: 513-24 (2008)

More data for this
Ligand-Target Pair