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There are 71 purchasable compounds for target: ADP-ribosylation factor GTPase-activating protein 1

Wt: 396.8
BDBM32341
Wt: 429.9
BDBM34388
Wt: 366.4
BDBM41188
Wt: 376.7
BDBM41086
Wt: 413.4
BDBM43208
Wt: 435.5
BDBM43011
Wt: 311.3
BDBM48131
Wt: 427.4
BDBM52271
Wt: 372.4
BDBM67993
Wt: 337.2
BDBM67822
Wt: 356.3
BDBM69756
Wt: 319.3
BDBM75956
Wt: 391.3
BDBM88864
Wt: 341.4
BDBM95195
Wt: 431.3
BDBM95196
Displayed 1 to 15 (of 71 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 32341,34388,41188,41086,43208,43011,48131,52271,67993,67822,69756,75956,88864,95195,95196   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM69756
PNG
(4-[(2-pyridin-4-yl-4-quinazolinyl)amino]benzoic ac...)
Show SMILES COC(=O)c1ccc(Nc2nc(nc3ccccc23)-c2ccncc2)cc1
Show InChI InChI=1S/C21H16N4O2/c1-27-21(26)15-6-8-16(9-7-15)23-20-17-4-2-3-5-18(17)24-19(25-20)14-10-12-22-13-11-14/h2-13H,1H3,(H,23,24,25)
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n/an/a 9.84E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM67993
PNG
((Z)-3-(1,3-diphenyl-4-pyrazolyl)-N-(2-thiazolyl)-2...)
Show SMILES O=C(Nc1nccs1)\C=C/c1cn(nc1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H16N4OS/c26-19(23-21-22-13-14-27-21)12-11-17-15-25(18-9-5-2-6-10-18)24-20(17)16-7-3-1-4-8-16/h1-15H,(H,22,23,26)/b12-11-
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n/an/a 3.21E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM41188
PNG
(MLS000111800 | SMR000107719 | cid_2909321)
Show SMILES COc1ccc(cc1)-n1c2nncn2c2sc3CC(C)CCc3c2c1=O
Show InChI InChI=1S/C19H18N4O2S/c1-11-3-8-14-15(9-11)26-18-16(14)17(24)23(19-21-20-10-22(18)19)12-4-6-13(25-2)7-5-12/h4-7,10-11H,3,8-9H2,1-2H3
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n/an/a 2.31E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM75956
PNG
(3-Methyl-benzofuran-2-carboxylic acid (4-tetrazol-...)
Show SMILES Cc1c(oc2ccccc12)C(=O)Nc1ccc(cc1)-n1cnnn1
Show InChI InChI=1S/C17H13N5O2/c1-11-14-4-2-3-5-15(14)24-16(11)17(23)19-12-6-8-13(9-7-12)22-10-18-20-21-22/h2-10H,1H3,(H,19,23)
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n/an/a 7.85E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM95195
PNG
(3-hydroxy-2-naphthalenecarboxylic acid [2-(3,5-dim...)
Show SMILES CC1CC(C)CN(C1)C(=O)COC(=O)c1cc2ccccc2cc1O
Show InChI InChI=1S/C20H23NO4/c1-13-7-14(2)11-21(10-13)19(23)12-25-20(24)17-8-15-5-3-4-6-16(15)9-18(17)22/h3-6,8-9,13-14,22H,7,10-12H2,1-2H3
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n/an/a>1.65E+5n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM48131
PNG
(1H-indazole-3-carboxylic acid [2-keto-2-(1,2,5-tri...)
Show SMILES Cc1cc(C(=O)COC(=O)c2n[nH]c3ccccc23)c(C)n1C
Show InChI InChI=1S/C17H17N3O3/c1-10-8-13(11(2)20(10)3)15(21)9-23-17(22)16-12-6-4-5-7-14(12)18-19-16/h4-8H,9H2,1-3H3,(H,18,19)
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n/an/a 3.24E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay




PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM34388
PNG
(MLS000085595 | N-[5-(4-chlorophenyl)-1,2,4-thiadia...)
Show SMILES Clc1ccc(cc1)-c1nc(NC(=O)CSc2nnnn2-c2ccccc2)ns1
Show InChI InChI=1S/C17H12ClN7OS2/c18-12-8-6-11(7-9-12)15-20-16(22-28-15)19-14(26)10-27-17-21-23-24-25(17)13-4-2-1-3-5-13/h1-9H,10H2,(H,19,22,26)
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n/an/a 3.76E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM95196
PNG
(5-(2,5-dichlorophenyl)-N-[4-(4-morpholinylmethyl)p...)
Show SMILES Clc1ccc(Cl)c(c1)-c1ccc(o1)C(=O)Nc1ccc(CN2CCOCC2)cc1
Show InChI InChI=1S/C22H20Cl2N2O3/c23-16-3-6-19(24)18(13-16)20-7-8-21(29-20)22(27)25-17-4-1-15(2-5-17)14-26-9-11-28-12-10-26/h1-8,13H,9-12,14H2,(H,25,27)
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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM67822
PNG
(1-[2-(2,4-dichlorophenoxy)ethyl]-3-methyl-1,3-dihy...)
Show SMILES Cn1c2ccccc2n(CCOc2ccc(Cl)cc2Cl)c1=O
Show InChI InChI=1S/C16H14Cl2N2O2/c1-19-13-4-2-3-5-14(13)20(16(19)21)8-9-22-15-7-6-11(17)10-12(15)18/h2-7,10H,8-9H2,1H3
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n/an/a 1.84E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM52271
PNG
(3-(4-fluorophenyl)-7,8-dimethoxy-5-(4-methylbenzyl...)
Show SMILES COc1cc2n(Cc3ccc(C)cc3)cc3c(nnc3c2cc1OC)-c1ccc(F)cc1
Show InChI InChI=1S/C26H22FN3O2/c1-16-4-6-17(7-5-16)14-30-15-21-25(18-8-10-19(27)11-9-18)28-29-26(21)20-12-23(31-2)24(32-3)13-22(20)30/h4-13,15H,14H2,1-3H3
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n/an/a 7.00E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM32341
PNG
(5-(3-Chloro-phenyl)-furan-2-carboxylic acid (4-mor...)
Show SMILES Clc1cccc(c1)-c1ccc(o1)C(=O)Nc1ccc(CN2CCOCC2)cc1
Show InChI InChI=1S/C22H21ClN2O3/c23-18-3-1-2-17(14-18)20-8-9-21(28-20)22(26)24-19-6-4-16(5-7-19)15-25-10-12-27-13-11-25/h1-9,14H,10-13,15H2,(H,24,26)
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n/an/a 8.17E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM43011
PNG
(2-(6-Amino-3,5-dicyano-4-thiophen-2-yl-pyridin-2-y...)
Show SMILES COc1ccccc1CNC(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N
Show InChI InChI=1S/C21H17N5O2S2/c1-28-16-6-3-2-5-13(16)11-25-18(27)12-30-21-15(10-23)19(17-7-4-8-29-17)14(9-22)20(24)26-21/h2-8H,11-12H2,1H3,(H2,24,26)(H,25,27)
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n/an/a 4.32E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM41086
PNG
(MLS000582064 | N-[3-chloranyl-4-(2-oxidanylidenech...)
Show SMILES Clc1cc(NC(=O)c2cccnc2)ccc1-c1cc2ccccc2oc1=O
Show InChI InChI=1S/C21H13ClN2O3/c22-18-11-15(24-20(25)14-5-3-9-23-12-14)7-8-16(18)17-10-13-4-1-2-6-19(13)27-21(17)26/h1-12H,(H,24,25)
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n/an/a 1.79E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM88864
PNG
(2-(2,4-Dichloro-benzylsulfanyl)-6,7,8,9-tetrahydro...)
Show SMILES Nc1nc(SCc2ccc(Cl)cc2Cl)nc2nc3CCCCc3cc12
Show InChI InChI=1S/C18H16Cl2N4S/c19-12-6-5-11(14(20)8-12)9-25-18-23-16(21)13-7-10-3-1-2-4-15(10)22-17(13)24-18/h5-8H,1-4,9H2,(H2,21,22,23,24)
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n/an/a 2.38E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
ADP-ribosylation factor GTPase-activating protein 1


(Rattus norvegicus)
BDBM43208
PNG
(4-benzyl-N-[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1...)
Show SMILES O=C(Nc1nnc(o1)-c1ccc2OCCOc2c1)c1ccc(Cc2ccccc2)cc1
Show InChI InChI=1S/C24H19N3O4/c28-22(18-8-6-17(7-9-18)14-16-4-2-1-3-5-16)25-24-27-26-23(31-24)19-10-11-20-21(15-19)30-13-12-29-20/h1-11,15H,12-14H2,(H,25,27,28)
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n/an/a 7.92E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

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PubChem Bioassay (2012)

More data for this
Ligand-Target Pair