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There are 1 purchasable compounds for target: ATP-binding cassette transporter sub-family C member 8

Wt: 452.5
BDBM50153520
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153520   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sulfonylurea receptor 1


(Homo sapiens)
BDBM50153520
PNG
((S)-2-ethoxy-4-(2-(3-methyl-1-(2-(piperidin-1-yl)p...)
Show SMILES CCOc1cc(CC(=O)N[C@@H](CC(C)C)c2ccccc2N2CCCCC2)ccc1C(O)=O
Show InChI InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1
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KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 106n/an/an/an/an/an/a



University of Mainz

Curated by ChEMBL


Assay Description
In vitro displacement of [3H]-glibenclamide (IC50=0.61) from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)


Bioorg Med Chem Lett 14: 5205-9 (2004)

More data for this
Ligand-Target Pair
Sulfonylurea receptor 1


(Homo sapiens)
BDBM50153520
PNG
((S)-2-ethoxy-4-(2-(3-methyl-1-(2-(piperidin-1-yl)p...)
Show SMILES CCOc1cc(CC(=O)N[C@@H](CC(C)C)c2ccccc2N2CCCCC2)ccc1C(O)=O
Show InChI InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/a 50n/an/an/an/an/a



University of Mainz

Curated by ChEMBL


Assay Description
Displacement of [3H]glibenclamide from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)


Bioorg Med Chem Lett 14: 5205-9 (2004)

More data for this
Ligand-Target Pair