BindingDB logo
myBDB logout

There are 23 purchasable compounds for target: AFABP

Wt: 280.4
BDBM22231
Purchase
Wt: 304.4
BDBM22319
Purchase
Wt: 282.4
BDBM50150484
Purchase
Wt: 249.6
BDBM50152892
Purchase
Wt: 311.7
BDBM50152893
Purchase
Wt: 263.7
BDBM50152897
Purchase
Wt: 256.4
BDBM50152850
Purchase
Wt: 239.2
BDBM50152856
Purchase
Wt: 225.2
BDBM50152869
Purchase
Wt: 474.5
BDBM50212873
Purchase
Wt: 284.4
BDBM50240485
Purchase
Wt: 282.4
BDBM50250904
Purchase
Wt: 337.3
BDBM50310988
Purchase
Wt: 403.5
BDBM50319697
Purchase
Wt: 277.7
BDBM50319698
Purchase
Displayed 1 to 15 (of 27 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22231,22319,50150484,50152892,50152893,50152897,50152850,50152856,50152869,50212873,50240485,50250904,50310988,50319697,50319698   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty acid-binding protein, adipocyte


(Rattus norvegicus)
BDBM50212873
PNG
(((2'-(5-ETHYL-3,4-DIPHENYL-1H-PYRAZOL-1-YL)-3-BIPH...)
Show SMILES CCc1c(c(nn1-c1ccccc1-c1cccc(OCC(O)=O)c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C31H26N2O3/c1-2-27-30(22-12-5-3-6-13-22)31(23-14-7-4-8-15-23)32-33(27)28-19-10-9-18-26(28)24-16-11-17-25(20-24)36-21-29(34)35/h3-20H,2,21H2,1H3,(H,34,35)
PDB
MMDB

Reactome pathway

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents

AffyNet 
PDB
Article
PubMed
29n/an/an/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat ap2 by fluorescent 1,8-anilino-8-naphthalene sulfonate assay


Eur J Med Chem 52: 70-81 (2012)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Activity Spreadsheet -- ITC Data from BindingDB

Found 4 hits for monomerid = 22231,22319,50150484,50152892,50152893,50152897,50152850,50152856,50152869,50212873,50240485,50250904,50310988,50319697,50319698
Cell (A)Syringe (B)Cell
Links
Syringe
Links
Cell + Syr
Links
ΔG°
kcal/mole
-TΔS°
kcal/mole
ΔH°
kcal/mole
log KpHTemp
°C
Mannoprotein ligand-binding domain 2 (Mp1p-LBD2)

(Talaromyces marneffei)
BDBM22319
JPEG
((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)
GoogleScholar
PDB
CHEBI
KEGG
MMDB
PC cid
PC sid
PDB
-11.23.33-14.27.89837



The University of Hong Kong





Cell Chem Biol 24: 182-194 (2017)

Mannoprotein ligand-binding domain 2 (Mp1p-LBD2)

(Talaromyces marneffei)
BDBM22319
JPEG
((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)
GoogleScholar
PDB
CHEBI
KEGG
MMDB
PC cid
PC sid
PDB
-12.32.30-11.08.64837



The University of Hong Kong





Cell Chem Biol 24: 182-194 (2017)

Mannoprotein ligand-binding domain 2 (Mp1p-LBD2 I332A)

(Talaromyces marneffei)
BDBM22319
JPEG
((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)
GoogleScholar
PDB
CHEBI
KEGG
MMDB
PC cid
PC sid
PDB
-8.186.44-14.55.77837



The University of Hong Kong





Cell Chem Biol 24: 182-194 (2017)

Mannoprotein ligand-binding domain 2 (Mp1p-LBD2 V309D)

(Talaromyces marneffei)
BDBM22319
JPEG
((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)
GoogleScholar
PDB
CHEBI
KEGG
MMDB
PC cid
PC sid
PDB
-7.691.93-9.315.42837



The University of Hong Kong





Cell Chem Biol 24: 182-194 (2017)