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There are 2 purchasable compounds for target: Aminoacylproline aminopeptidase

Wt: 407.3
BDBM11162
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Wt: 459.5
BDBM50078401
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11162,50078401   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Xaa-Pro aminopeptidase 1


(Homo sapiens)
BDBM50078401
PNG
((S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C23H33N5O5/c1-14(20(25)30)26-21(31)17-9-5-11-27(17)22(32)18-10-6-12-28(18)23(33)19(29)16(24)13-15-7-3-2-4-8-15/h2-4,7-8,14,16-19,29H,5-6,9-13,24H2,1H3,(H2,25,30)(H,26,31)/t14-,16+,17-,18-,19-/m0/s1
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MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Inhibition against Aminopeptidase P from human platelets.


J Med Chem 42: 2394-402 (1999)

More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 1


(Homo sapiens)
BDBM11162
PNG
((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)
Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F
Show InChI InChI=1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1
PDB
MMDB

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UniProtKB/SwissProt

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antibodypedia
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CHEMBL
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PC cid
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PDB
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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of amino peptidase P


J Med Chem 51: 589-602 (2008)

More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 1


(Homo sapiens)
BDBM50078401
PNG
((S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C23H33N5O5/c1-14(20(25)30)26-21(31)17-9-5-11-27(17)22(32)18-10-6-12-28(18)23(33)19(29)16(24)13-15-7-3-2-4-8-15/h2-4,7-8,14,16-19,29H,5-6,9-13,24H2,1H3,(H2,25,30)(H,26,31)/t14-,16+,17-,18-,19-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.10E+4n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Inhibition against cytosolic Aminopeptidase P from human heart.


J Med Chem 42: 2394-402 (1999)

More data for this
Ligand-Target Pair