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There are 9 purchasable compounds for target: ABP

Wt: 290.4
BDBM18161
Wt: 281.3
BDBM50000999
Wt: 340.4
BDBM45440
Wt: 184.2
BDBM50046201
Wt: 294.3
BDBM50121455
Wt: 294.3
BDBM50121458
Wt: 123.1
BDBM50161138
Wt: 74.0
BDBM50207159
Wt: 284.3
BDBM50367916

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 18161,50000999,45440,50046201,50121455,50121458,50161138,50207159,50367916   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Diamine oxidase


(Homo sapiens)
BDBM50000999
PNG
(CHEBI:81724 | DIMINAZENE)
Show SMILES NC(=N)c1ccc(N\N=N\c2ccc(cc2)C(N)=N)cc1
Show InChI InChI=1S/C14H15N7/c15-13(16)9-1-5-11(6-2-9)19-21-20-12-7-3-10(4-8-12)14(17)18/h1-8H,(H3,15,16)(H3,17,18)(H,19,20)
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13n/an/an/an/an/an/an/an/a



Xavier University of Louisiana

Curated by ChEMBL


Assay Description
Mixed type inhibition of recombinant human DAO expressed in drosophila S2 cells


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Diamine oxidase


(Homo sapiens)
BDBM50207159
PNG
(2-aminoguanidine | 2-azanylguanidine | AG | AMINOG...)
Show SMILES NNC(N)=N
Show InChI InChI=1S/CH6N4/c2-1(3)5-4/h4H2,(H4,2,3,5)
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140n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for ability of the compound to competitively inhibit hog kidney diamine oxidase (DAO) in a spectrometric assay


Citation and Details
More data for this
Ligand-Target Pair
Diamine oxidase


(Homo sapiens)
BDBM45440
PNG
(4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...)
Show SMILES NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1
Show InChI InChI=1S/C19H24N4O2/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23)
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290n/an/an/an/an/an/an/an/a



Xavier University of Louisiana

Curated by ChEMBL


Assay Description
Mixed type inhibition of recombinant human DAO expressed in drosophila S2 cells


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Diamine oxidase


(Homo sapiens)
BDBM50121458
PNG
(1-[3-(2-Hydroxy-phenyl)-5-o-tolyl-4,5-dihydro-pyra...)
Show SMILES CC(=O)N1N=C(CC1c1ccccc1C)c1ccccc1O
Show InChI InChI=1S/C18H18N2O2/c1-12-7-3-4-8-14(12)17-11-16(19-20(17)13(2)21)15-9-5-6-10-18(15)22/h3-10,17,22H,11H2,1-2H3
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5.50E+3n/an/an/an/an/an/an/an/a



Università di Roma La Sapienza

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against Swine kidney diamine oxidase (SKDAO)


Bioorg Med Chem Lett 12: 3629-33 (2002)

More data for this
Ligand-Target Pair
Diamine oxidase


(Homo sapiens)
BDBM50121455
PNG
(1-[3-(2-Hydroxy-phenyl)-5-m-tolyl-4,5-dihydro-pyra...)
Show SMILES CC(=O)N1N=C(CC1c1cccc(C)c1)c1ccccc1O
Show InChI InChI=1S/C18H18N2O2/c1-12-6-5-7-14(10-12)17-11-16(19-20(17)13(2)21)15-8-3-4-9-18(15)22/h3-10,17,22H,11H2,1-2H3
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8.00E+3n/an/an/an/an/an/an/an/a



Università di Roma La Sapienza

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against Swine kidney diamine oxidase (SKDAO)


Bioorg Med Chem Lett 12: 3629-33 (2002)

More data for this
Ligand-Target Pair
Diamine oxidase


(Homo sapiens)
BDBM50161138
PNG
(4-(aminomethyl)pyridin-3-amine dihydrochloride | C...)
Show SMILES NCc1ccncc1N
Show InChI InChI=1S/C6H9N3/c7-3-5-1-2-9-4-6(5)8/h1-2,4H,3,7-8H2
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n/an/a 300n/an/an/an/an/an/a



Universit£ di Genova

Curated by ChEMBL


Assay Description
Inhibition of putrescine binding to against Diamine oxidase of porcine kidney


Citation and Details
More data for this
Ligand-Target Pair
Testis-specific androgen-binding protein


(Rattus norvegicus)
BDBM18161
PNG
((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
Show InChI InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1
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n/an/a 23n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Inhibition of rat androgen binding protein (rABP)


J Med Chem 33: 129-32 (1990)

More data for this
Ligand-Target Pair
Testis-specific androgen-binding protein


(Rattus norvegicus)
BDBM50367916
PNG
(METHYLTRIENOLONE | Metribolone | R-1881)
Show SMILES C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3C=C[C@]12C
Show InChI InChI=1S/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/m1/s1
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n/an/a 3.70n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Inhibition of rat androgen binding protein (rABP) (n=9)


J Med Chem 33: 129-32 (1990)

More data for this
Ligand-Target Pair
Diamine oxidase


(Rattus norvegicus)
BDBM50046201
PNG
((2E)-2-((2E)-2-{[(E)-amino(imino)methyl]hydrazono}...)
Show SMILES CC(C=NNC(N)=N)=NN=C(N)N
Show InChI InChI=1S/C5H12N8/c1-3(11-13-5(8)9)2-10-12-4(6)7/h2H,1H3,(H4,6,7,12)(H4,8,9,13)
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n/an/a 1.50E+3n/an/an/an/an/an/a



Ciba-Geigy AG

Curated by ChEMBL


Assay Description
In vitro inhibition of Diamine oxidase (DAO) from rat small intestine.


J Med Chem 36: 46-54 (1993)

More data for this
Ligand-Target Pair