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There are 7 purchasable compounds for target: ALADH

Wt: 238.6
BDBM50441097
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Wt: 283.1
BDBM50441098
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Wt: 383.4
BDBM50441100
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Wt: 378.3
BDBM50441101
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Wt: 176.1
BDBM50017193
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Wt: 252.2
BDBM50017190
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Wt: 162.1
BDBM50017194
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50441097,50441098,50441100,50441101,50017193,50017190,50017194   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Porphobilinogen synthase


(Homo sapiens)
BDBM50441097
PNG
(CHEMBL2430564)
Show SMILES OC(=O)c1cc(cs1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C11H7ClO2S/c12-9-3-1-7(2-4-9)8-5-10(11(13)14)15-6-8/h1-6H,(H,13,14)
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PubMed
n/an/a 8.53E+4n/an/an/an/an/an/a



University Hospital of Bonn

Curated by ChEMBL


Assay Description
Inhibition of human ALADH after 20 mins


Citation and Details
More data for this
Ligand-Target Pair
Porphobilinogen synthase


(Homo sapiens)
BDBM50441098
PNG
(CHEMBL2430563)
Show SMILES OC(=O)c1cc(cs1)-c1ccc(Br)cc1
Show InChI InChI=1S/C11H7BrO2S/c12-9-3-1-7(2-4-9)8-5-10(11(13)14)15-6-8/h1-6H,(H,13,14)
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n/an/a 9.97E+4n/an/an/an/an/an/a



University Hospital of Bonn

Curated by ChEMBL


Assay Description
Inhibition of human ALADH after 20 mins


Citation and Details
More data for this
Ligand-Target Pair
Porphobilinogen synthase


(Homo sapiens)
BDBM50441100
PNG
(CHEMBL2430572)
Show SMILES OC(=O)c1ccc2n(Cc3ccc(F)cc3)c(=O)n(CCN3CCCC3)c2c1
Show InChI InChI=1S/C21H22FN3O3/c22-17-6-3-15(4-7-17)14-25-18-8-5-16(20(26)27)13-19(18)24(21(25)28)12-11-23-9-1-2-10-23/h3-8,13H,1-2,9-12,14H2,(H,26,27)
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n/an/a>1.00E+6n/an/an/an/an/an/a



University Hospital of Bonn

Curated by ChEMBL


Assay Description
Inhibition of human ALADH after 20 mins


Citation and Details
More data for this
Ligand-Target Pair
Porphobilinogen synthase


(Homo sapiens)
BDBM50441101
PNG
(CHEMBL2430571)
Show SMILES OC(=O)c1ccc2n(Cc3ccc(F)cc3)c(=O)n(Cc3ncccn3)c2c1
Show InChI InChI=1S/C20H15FN4O3/c21-15-5-2-13(3-6-15)11-24-16-7-4-14(19(26)27)10-17(16)25(20(24)28)12-18-22-8-1-9-23-18/h1-10H,11-12H2,(H,26,27)
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n/an/a 1.19E+5n/an/an/an/an/an/a



University Hospital of Bonn

Curated by ChEMBL


Assay Description
Inhibition of human ALADH after 20 mins


Citation and Details
More data for this
Ligand-Target Pair
Delta-aminolevulinic acid dehydratase, chloroplastic


(Pisum sativum)
BDBM50017194
PNG
(CHEMBL1774061)
Show SMILES OC(=O)c1ccc2[nH]cnc2c1
Show InChI InChI=1S/C8H6N2O2/c11-8(12)5-1-2-6-7(3-5)10-4-9-6/h1-4H,(H,9,10)(H,11,12)
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n/an/a>5.00E+5n/an/an/an/an/an/a



University Hospital of Bonn

Curated by ChEMBL


Assay Description
Inhibition of Pisum sativum PBGS using 5-ALA as substrate


Citation and Details
More data for this
Ligand-Target Pair
Porphobilinogen synthase


(Homo sapiens)
BDBM50017193
PNG
(CHEMBL3287369)
Show SMILES Cn1cnc2cc(ccc12)C(O)=O
Show InChI InChI=1S/C9H8N2O2/c1-11-5-10-7-4-6(9(12)13)2-3-8(7)11/h2-5H,1H3,(H,12,13)
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n/an/a 5.00E+5n/an/an/an/an/an/a



University Hospital of Bonn

Curated by ChEMBL


Assay Description
Inhibition of human PBGS using 5-ALA as substrate


Citation and Details
More data for this
Ligand-Target Pair
Porphobilinogen synthase


(Homo sapiens)
BDBM50017194
PNG
(CHEMBL1774061)
Show SMILES OC(=O)c1ccc2[nH]cnc2c1
Show InChI InChI=1S/C8H6N2O2/c11-8(12)5-1-2-6-7(3-5)10-4-9-6/h1-4H,(H,9,10)(H,11,12)
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n/an/a 5.11E+5n/an/an/an/an/an/a



University Hospital of Bonn

Curated by ChEMBL


Assay Description
Inhibition of human PBGS using 5-ALA as substrate


Citation and Details
More data for this
Ligand-Target Pair
Delta-aminolevulinic acid dehydratase, chloroplastic


(Pisum sativum)
BDBM50017190
PNG
(CHEMBL3287366)
Show SMILES OC(=O)c1ccc2n(Cc3ccccc3)cnc2c1
Show InChI InChI=1S/C15H12N2O2/c18-15(19)12-6-7-14-13(8-12)16-10-17(14)9-11-4-2-1-3-5-11/h1-8,10H,9H2,(H,18,19)
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n/an/a 1.82E+5n/an/an/an/an/an/a



University Hospital of Bonn

Curated by ChEMBL


Assay Description
Inhibition of Pisum sativum PBGS using 5-ALA as substrate


Citation and Details
More data for this
Ligand-Target Pair
Delta-aminolevulinic acid dehydratase, chloroplastic


(Pisum sativum)
BDBM50017193
PNG
(CHEMBL3287369)
Show SMILES Cn1cnc2cc(ccc12)C(O)=O
Show InChI InChI=1S/C9H8N2O2/c1-11-5-10-7-4-6(9(12)13)2-3-8(7)11/h2-5H,1H3,(H,12,13)
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PubMed
n/an/a 2.57E+5n/an/an/an/an/an/a



University Hospital of Bonn

Curated by ChEMBL


Assay Description
Inhibition of Pisum sativum PBGS using 5-ALA as substrate


Citation and Details
More data for this
Ligand-Target Pair
Porphobilinogen synthase


(Homo sapiens)
BDBM50017190
PNG
(CHEMBL3287366)
Show SMILES OC(=O)c1ccc2n(Cc3ccccc3)cnc2c1
Show InChI InChI=1S/C15H12N2O2/c18-15(19)12-6-7-14-13(8-12)16-10-17(14)9-11-4-2-1-3-5-11/h1-8,10H,9H2,(H,18,19)
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PubMed
n/an/a 2.13E+5n/an/an/an/an/an/a



University Hospital of Bonn

Curated by ChEMBL


Assay Description
Inhibition of human PBGS using 5-ALA as substrate


Citation and Details
More data for this
Ligand-Target Pair