Found 32 hits for monomerid = 18351,18353,18355,18358,50009001,50076963,50163440,50163445,50182798,50234564,50241137,50242271,50263044,50259956,50285808 Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM18351
 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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Similars AffyNet 
| Article
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Tested in vitro for the inhibition constant against human lysosomal alpha-glucosidase |
Bioorg Med Chem Lett 7: 355-360 (1997)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM18353
 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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CHEMBL PC cid PC sid UniChem
Patents
Similars AffyNet 
| Article
| 420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Tested in vitro for the inhibition constant against human lysosomal alpha-glucosidase |
Bioorg Med Chem Lett 7: 355-360 (1997)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM18351
 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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Similars AffyNet 
| PubMed
| 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Berlin
Curated by ChEMBL
| Assay Description Inhibitory activity against alpha-glucosidase of yeast |
Bioorg Med Chem Lett 9: 615-8 (1999)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50076963
 ((3R,5R)-2-Hydroxymethyl-1-methyl-piperidine-3,4,5-...)Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
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Similars AffyNet 
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| 5.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by ChEMBL
| Assay Description Inhibitory potency for brewer's yeast alpha-glucosidase in 0.1 M sodium phosphate buffer at pH 6.55. |
Bioorg Med Chem Lett 9: 1255-60 (1999)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50076963
 ((3R,5R)-2-Hydroxymethyl-1-methyl-piperidine-3,4,5-...)Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
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| 3.69E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by ChEMBL
| Assay Description Inhibitory potency for brewer's yeast alpha-glucosidase in 0.01 mM EDTA, 0.01 mM PIPES and 0.2 M NaOAc at pH 6.5. |
Bioorg Med Chem Lett 9: 1255-60 (1999)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50285808
 (6N-benzyl-2,3,4,5-tetrahydro-6-pyridiniumamine)Show InChI InChI=1S/C12H16N2/c1-2-6-11(7-3-1)10-14-12-8-4-5-9-13-12/h1-3,6-7H,4-5,8-10H2,(H,13,14)/p+1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid UniChem AffyNet 
| Article
| 3.70E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition against beta-glucosidase in sweet almond |
Citation and Details
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM18355
 ((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)Show InChI InChI=1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
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Similars AffyNet 
| Article PubMed
| n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description Inhibition of human lysosomal alpha glucosidase |
Bioorg Med Chem Lett 19: 6600-3 (2009)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM18351
 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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Similars AffyNet 
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description Inhibition of lysosomal alpha-glucosidase by HPLC |
J Med Chem 53: 689-98 (2010)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50242271
 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...)Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
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Similars AffyNet 
| DrugBank Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description Inhibition of lysosomal alpha-glucosidase by HPLC |
J Med Chem 53: 689-98 (2010)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM18355
 ((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)Show InChI InChI=1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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Similars AffyNet 
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description Inhibition of lysosomal alpha-glucosidase by HPLC |
J Med Chem 53: 689-98 (2010)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50163440
 ((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
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Similars AffyNet 
| Article PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description Inhibition of lysosomal alpha-glucosidase by HPLC |
J Med Chem 53: 689-98 (2010)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50163445
 ((2S,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m0/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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Similars AffyNet 
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description Inhibition of lysosomal alpha-glucosidase by HPLC |
J Med Chem 53: 689-98 (2010)
|
More data for this Ligand-Target Pair | |
alpha-glucosidase (Gaa)
(Mus musculus (Mouse)) | BDBM18358
 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)Show SMILES CCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C15H31NO4/c1-2-3-4-5-6-7-8-9-16-10-13(18)15(20)14(19)12(16)11-17/h12-15,17-20H,2-11H2,1H3/t12-,13+,14-,15-/m1/s1 | UniProtKB/SwissProt
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Similars AffyNet 
| Article
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of maltase in mouse intestinal input by glucose release assay |
ACS Med Chem Lett 2: 119-123 (2011)
|
More data for this Ligand-Target Pair | |
alpha-glucosidase (Gaa)
(Mus musculus (Mouse)) | BDBM18355
 ((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)Show InChI InChI=1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet 
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Similars AffyNet 
| Article
| n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of maltase in mouse intestinal input by glucose release assay |
ACS Med Chem Lett 2: 119-123 (2011)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM18351
 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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CHEMBL KEGG MMDB PC cid PC sid UniChem
Patents
Similars AffyNet 
| Article
| n/a | n/a | 9.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibitory activity was determined against baker's yeast Alpha-Glucosidase |
Citation and Details
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50009001
 (5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)Show InChI InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H | PDB
NCI pathway KEGG
UniProtKB/SwissProt
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Similars AffyNet 
| Article PubMed
| n/a | n/a | 5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Indian Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of maltase |
Bioorg Med Chem Lett 18: 1659-62 (2008)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50234564
 (CHEMBL259905)Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
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Similars AffyNet 
| Article PubMed
| n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibition of alpha-glucosidase |
J Nat Prod 68: 1238-42 (2005)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM18351
 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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CHEMBL KEGG MMDB PC cid PC sid UniChem
Patents
Similars AffyNet 
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibition of human lysosomal alpha-glucosidase |
Bioorg Med Chem 16: 7330-6 (2008)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50263044
 (CHEMBL476960 | Voglibose)Show SMILES OCC(CO)N[C@H]1C[C@](O)(CO)[C@@H](O)[C@H](O)[C@H]1O Show InChI InChI=1S/C10H21NO7/c12-2-5(3-13)11-6-1-10(18,4-14)9(17)8(16)7(6)15/h5-9,11-18H,1-4H2/t6-,7-,8+,9-,10-/m0/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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Similars AffyNet 
| Article PubMed
| n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibition of human lysosomal alpha-glucosidase |
Bioorg Med Chem 16: 7330-6 (2008)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50241137
 (CHEMBL222396 | Valiolamine)Show SMILES N[C@H]1C[C@](O)(CO)[C@@H](O)[C@H](O)[C@H]1O Show InChI InChI=1S/C7H15NO5/c8-3-1-7(13,2-9)6(12)5(11)4(3)10/h3-6,9-13H,1-2,8H2/t3-,4-,5+,6-,7-/m0/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
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Similars AffyNet 
| Article PubMed
| n/a | n/a | 5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibition of human lysosomal alpha-glucosidase |
Bioorg Med Chem 16: 7330-6 (2008)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50242271
 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...)Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
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Similars AffyNet 
| DrugBank Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibition of human lysosomal alpha-glucosidase |
Bioorg Med Chem 16: 7330-6 (2008)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50259956
 (2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...)Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4-,5-,6+,7+/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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Similars AffyNet 
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibition of human lysosomal alpha-glucosidase |
Bioorg Med Chem 16: 7330-6 (2008)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50242271
 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...)Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
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| DrugBank Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibition of maltase in human Caco-2 cell model system after 2 hrs |
Bioorg Med Chem 16: 7330-6 (2008)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM18351
 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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Patents
Similars AffyNet 
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibition of maltase in human Caco-2 cell model system after 2 hrs |
Bioorg Med Chem 16: 7330-6 (2008)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50259956
 (2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...)Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4-,5-,6+,7+/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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CHEMBL PC cid PC sid UniChem
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Similars AffyNet 
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibition of maltase in human Caco-2 cell model system after 2 hrs |
Bioorg Med Chem 16: 7330-6 (2008)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM18351
 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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CHEMBL KEGG MMDB PC cid PC sid UniChem
Patents
Similars AffyNet 
| Article PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description Inhibition of human lysosomal alpha glucosidase |
Bioorg Med Chem Lett 19: 6600-3 (2009)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50182798
 ((3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,...)Show InChI InChI=1S/C5H11NO3/c7-3-1-6-2-4(8)5(3)9/h3-9H,1-2H2/t3-,4+,5+ | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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Similars AffyNet 
| Article
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was evaluated for inhibition of alpha-glucosidase from yeast(sigma G 7256). |
Bioorg Med Chem Lett 6: 553-558 (1996)
|
More data for this Ligand-Target Pair | |
alpha-glucosidase (Gaa)
(Mus musculus (Mouse)) | BDBM50259956
 (2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...)Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4-,5-,6+,7+/m1/s1 | UniProtKB/SwissProt
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| US Patent
| n/a | n/a | n/a | n/a | 2.81E+5 | n/a | n/a | n/a | n/a |
Amicus Therapeutics, Inc.
US Patent
| Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... |
US Patent US9181184 (2015)
|
More data for this Ligand-Target Pair | |
alpha-glucosidase (Gaa)
(Mus musculus (Mouse)) | BDBM18355
 ((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)Show InChI InChI=1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1 | UniProtKB/SwissProt
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| US Patent
| n/a | n/a | n/a | n/a | 1.18E+4 | n/a | n/a | n/a | n/a |
Amicus Therapeutics, Inc.
US Patent
| Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... |
US Patent US9181184 (2015)
|
More data for this Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens) | BDBM50263044
 (CHEMBL476960 | Voglibose)Show SMILES OCC(CO)N[C@H]1C[C@](O)(CO)[C@@H](O)[C@H](O)[C@H]1O Show InChI InChI=1S/C10H21NO7/c12-2-5(3-13)11-6-1-10(18,4-14)9(17)8(16)7(6)15/h5-9,11-18H,1-4H2/t6-,7-,8+,9-,10-/m0/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet 
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| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibition of maltase in human Caco-2 cell model system after 2 hrs |
Bioorg Med Chem 16: 7330-6 (2008)
|
More data for this Ligand-Target Pair | |
alpha-glucosidase (Gaa)
(Mus musculus (Mouse)) | BDBM18351
 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 | UniProtKB/SwissProt
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Patents
Similars AffyNet 
| US Patent
| n/a | n/a | n/a | n/a | 9.88E+4 | n/a | n/a | n/a | n/a |
Amicus Therapeutics, Inc.
US Patent
| Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... |
US Patent US9181184 (2015)
|
More data for this Ligand-Target Pair | |
alpha-glucosidase (Gaa)
(Mus musculus (Mouse)) | BDBM18353
 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1 | UniProtKB/SwissProt
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Similars AffyNet 
| US Patent
| n/a | n/a | n/a | n/a | 7.45E+4 | n/a | n/a | n/a | n/a |
Amicus Therapeutics, Inc.
US Patent
| Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... |
US Patent US9181184 (2015)
|
More data for this Ligand-Target Pair | |