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There are 5 purchasable compounds for target: AdoMet synthetase 1

Wt: 145.1
BDBM50070634
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Wt: 131.1
BDBM50070635
Purchase
Wt: 147.1
BDBM50070636
Purchase
Wt: 129.1
BDBM50070638
Purchase
Wt: 161.2
BDBM50070639
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50070634,50070635,50070636,50070638,50070639   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
S-adenosylmethionine synthetase (MAT 1 and MAT 2)


(Rattus norvegicus)
BDBM50070638
PNG
(1-AMINOCYCLOPENTANECARBOXYLIC ACID | 1-Amino-cyclo...)
Show SMILES NC1(CCCC1)C(O)=O
Show InChI InChI=1S/C6H11NO2/c7-6(5(8)9)3-1-2-4-6/h1-4,7H2,(H,8,9)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PubMed
5.16E+5n/an/an/an/an/an/an/an/a



U.M.R. 6519

Curated by ChEMBL


Assay Description
Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liver


Bioorg Med Chem Lett 8: 1629-34 (1999)

More data for this
Ligand-Target Pair
S-adenosylmethionine synthetase (MAT 1 and MAT 2)


(Rattus norvegicus)
BDBM50070635
PNG
((R)-3-Amino-tetrahydro-furan-3-carboxylic acid | C...)
Show SMILES N[C@@]1(CCOC1)C(O)=O
Show InChI InChI=1S/C5H9NO3/c6-5(4(7)8)1-2-9-3-5/h1-3,6H2,(H,7,8)/t5-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
7.50E+5n/an/an/an/an/an/an/an/a



U.M.R. 6519

Curated by ChEMBL


Assay Description
Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liver


Bioorg Med Chem Lett 8: 1629-34 (1999)

More data for this
Ligand-Target Pair
S-adenosylmethionine synthetase (MAT 1 and MAT 2)


(Rattus norvegicus)
BDBM50070634
PNG
(4-Amino-tetrahydro-pyran-4-carboxylic acid | CHEMB...)
Show SMILES NC1(CCOCC1)C(O)=O
Show InChI InChI=1S/C6H11NO3/c7-6(5(8)9)1-3-10-4-2-6/h1-4,7H2,(H,8,9)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

AffyNet 
PubMed
1.00E+6n/an/an/an/an/an/an/an/a



U.M.R. 6519

Curated by ChEMBL


Assay Description
Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liver


Bioorg Med Chem Lett 8: 1629-34 (1999)

More data for this
Ligand-Target Pair
S-adenosylmethionine synthetase (MAT 1 and MAT 2)


(Rattus norvegicus)
BDBM50070636
PNG
((S)-3-Amino-tetrahydro-thiophene-3-carboxylic acid...)
Show SMILES N[C@@]1(CCSC1)C(O)=O
Show InChI InChI=1S/C5H9NO2S/c6-5(4(7)8)1-2-9-3-5/h1-3,6H2,(H,7,8)/t5-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
1.04E+6n/an/an/an/an/an/an/an/a



U.M.R. 6519

Curated by ChEMBL


Assay Description
Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liver


Bioorg Med Chem Lett 8: 1629-34 (1999)

More data for this
Ligand-Target Pair
S-adenosylmethionine synthetase (MAT 1 and MAT 2)


(Rattus norvegicus)
BDBM50070639
PNG
(4-Amino-tetrahydro-thiopyran-4-carboxylic acid | C...)
Show SMILES NC1(CCSCC1)C(O)=O
Show InChI InChI=1S/C6H11NO2S/c7-6(5(8)9)1-3-10-4-2-6/h1-4,7H2,(H,8,9)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
3.00E+6n/an/an/an/an/an/an/an/a



U.M.R. 6519

Curated by ChEMBL


Assay Description
Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liver


Bioorg Med Chem Lett 8: 1629-34 (1999)

More data for this
Ligand-Target Pair