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There are 6 purchasable compounds for target: Lysozyme C

Compile data set for download or QSAR
Wt: 270.2
BDBM7458
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Wt: 407.4
BDBM79181
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Wt: 254.2
BDBM50077323
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Wt: 286.2
BDBM50142192
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Wt: 270.2
BDBM50142193
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Wt: 448.3
BDBM50366927
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 7458,79181,50077323,50142192,50142193,50366927   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysozyme C


(Rattus norvegicus)
BDBM50077323
PNG
(7,4'-Dihydroxyflavone | 7-hydroxy-2-(4-hydroxyphen...)
Show SMILES Oc1ccc(cc1)-c1cc(=O)c2ccc(O)cc2o1
Show InChI InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-8,16-17H
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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Kaohsiung Medical University

Curated by ChEMBL


Assay Description
Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CB


Bioorg Med Chem Lett 14: 1011-4 (2004)


Article DOI: 10.1016/j.bmcl.2003.11.074
BindingDB Entry DOI: 10.7270/Q2C829VG
More data for this
Ligand-Target Pair
Lysozyme C


(Rattus norvegicus)
BDBM79181
PNG
(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)
Show SMILES CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1
Show InChI InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3
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Article
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



Kaohsiung Medical University

Curated by ChEMBL


Assay Description
Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CB


Bioorg Med Chem Lett 14: 1011-4 (2004)


Article DOI: 10.1016/j.bmcl.2003.11.074
BindingDB Entry DOI: 10.7270/Q2C829VG
More data for this
Ligand-Target Pair
Lysozyme C


(Rattus norvegicus)
BDBM50366927
PNG
(CHEMBL1159471)
Show SMILES OC[C@H]1OC(Oc2cc(O)c3c(c2)oc(-c2ccc(O)cc2)c(O)c3=O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C21H20O11/c22-7-13-15(25)17(27)19(29)21(32-13)30-10-5-11(24)14-12(6-10)31-20(18(28)16(14)26)8-1-3-9(23)4-2-8/h1-6,13,15,17,19,21-25,27-29H,7H2/t13-,15-,17+,19-,21?/m1/s1
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PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Kaohsiung Medical University

Curated by ChEMBL


Assay Description
Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CB


Bioorg Med Chem Lett 14: 1011-4 (2004)


Article DOI: 10.1016/j.bmcl.2003.11.074
BindingDB Entry DOI: 10.7270/Q2C829VG
More data for this
Ligand-Target Pair
Lysozyme C


(Rattus norvegicus)
BDBM50142192
PNG
(3-(2,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-o...)
Show SMILES Oc1ccc(c(O)c1)-c1coc2cc(O)cc(O)c2c1=O
Show InChI InChI=1S/C15H10O6/c16-7-1-2-9(11(18)3-7)10-6-21-13-5-8(17)4-12(19)14(13)15(10)20/h1-6,16-19H
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n/an/a 9.70E+3n/an/an/an/an/an/a



Kaohsiung Medical University

Curated by ChEMBL


Assay Description
Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CB


Bioorg Med Chem Lett 14: 1011-4 (2004)


Article DOI: 10.1016/j.bmcl.2003.11.074
BindingDB Entry DOI: 10.7270/Q2C829VG
More data for this
Ligand-Target Pair
Lysozyme C


(Rattus norvegicus)
BDBM50142193
PNG
(2'-hydroxydaidzein | 3-(2,4-dihydroxyphenyl)-7-hyd...)
Show SMILES Oc1ccc(c(O)c1)-c1coc2cc(O)ccc2c1=O
Show InChI InChI=1S/C15H10O5/c16-8-1-3-10(13(18)5-8)12-7-20-14-6-9(17)2-4-11(14)15(12)19/h1-7,16-18H
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Article
PubMed
n/an/a 2.63E+4n/an/an/an/an/an/a



Kaohsiung Medical University

Curated by ChEMBL


Assay Description
Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CB


Bioorg Med Chem Lett 14: 1011-4 (2004)


Article DOI: 10.1016/j.bmcl.2003.11.074
BindingDB Entry DOI: 10.7270/Q2C829VG
More data for this
Ligand-Target Pair
Lysozyme C


(Rattus norvegicus)
BDBM7458
PNG
(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)cc2o1
Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
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Article
PubMed
n/an/a 1.77E+4n/an/an/an/an/an/a



Kaohsiung Medical University

Curated by ChEMBL


Assay Description
Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CB


Bioorg Med Chem Lett 14: 1011-4 (2004)


Article DOI: 10.1016/j.bmcl.2003.11.074
BindingDB Entry DOI: 10.7270/Q2C829VG
More data for this
Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 7458,79181,50077323,50142192,50142193,50366927
Cell (A)Syringe (B)Cell
Links
Syringe
Links
Cell + Syr
Links
ΔG°
kcal/mole
-TΔS°
kcal/mole
ΔH°
kcal/mole
log KpHTemp
°C
Transcriptional Regulator TtgR

(Pseudomonas putida)
BDBM7458
JPEG
(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
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PDB
CHEBI
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
-6.66-5.38-1.284.81730



Estacion Experimental del Zaidin





J Biol Chem 281: 7102-9 (2006)