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There are 3 purchasable compounds for target: AMP-activated protein kinase, alpha-2 subunit

Wt: 211.3
BDBM50436622
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Wt: 230.0
BDBM50436623
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Wt: 144.1
BDBM50436624
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50436622,50436623,50436624   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AMP-activated protein kinase, alpha-2 subunit


(Rattus norvegicus)
BDBM50436622
PNG
(CHEMBL568708)
Show SMILES CCOc1ccc2nc(S)sc2c1
Show InChI InChI=1S/C9H9NOS2/c1-2-11-6-3-4-7-8(5-6)13-9(12)10-7/h3-5H,2H2,1H3,(H,10,12)
PDB
MMDB

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UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 7.61E+4n/an/an/an/a



Bar Ilan University

Curated by ChEMBL


Assay Description
Activation of AMPK in rat L6 cells assessed as increase of [3H]dGlc uptake after 5 hrs


J Med Chem 56: 5335-50 (2014)

More data for this
Ligand-Target Pair
AMP-activated protein kinase, alpha-2 subunit


(Rattus norvegicus)
BDBM50436624
PNG
(CHEMBL1522339)
Show SMILES CCc1sc(N)nc1O
Show InChI InChI=1S/C5H8N2OS/c1-2-3-4(8)7-5(6)9-3/h8H,2H2,1H3,(H2,6,7)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 6.15E+4n/an/an/an/a



Bar Ilan University

Curated by ChEMBL


Assay Description
Activation of AMPK in rat L6 cells assessed as increase of [3H]dGlc uptake after 5 hrs


J Med Chem 56: 5335-50 (2014)

More data for this
Ligand-Target Pair
AMP-activated protein kinase, alpha-2 subunit


(Rattus norvegicus)
BDBM50436623
PNG
(CHEMBL2398100)
Show SMILES Brc1ccc2[nH]c(=O)sc2c1
Show InChI InChI=1S/C7H4BrNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 7.29E+4n/an/an/an/a



Bar Ilan University

Curated by ChEMBL


Assay Description
Activation of AMPK in rat L6 cells assessed as increase of [3H]dGlc uptake after 5 hrs


J Med Chem 56: 5335-50 (2014)

More data for this
Ligand-Target Pair