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There are 27 purchasable compounds for target: Arylamine N-acetyltransferase 2

Wt: 269.7
BDBM50181712
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Wt: 270.7
BDBM50181733
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Wt: 300.1
BDBM50241153
Wt: 239.2
BDBM50241155
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Wt: 253.3
BDBM50275067
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Wt: 253.3
BDBM50275068
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Wt: 311.4
BDBM50274856
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Wt: 235.3
BDBM50275072
Wt: 249.3
BDBM50275073
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Wt: 235.3
BDBM50274860
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Wt: 251.3
BDBM50275024
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Wt: 252.3
BDBM50275025
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Wt: 251.3
BDBM50275026
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Wt: 265.3
BDBM50275028
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Wt: 265.3
BDBM50275029
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Displayed 1 to 15 (of 27 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50181712,50181733,50241153,50241155,50275067,50275068,50274856,50275072,50275073,50274860,50275024,50275025,50275026,50275028,50275029   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50275024
PNG
((Z)-5-(4'-Hydroxybenzylidene)-3-methyl-2-thioxothi...)
Show SMILES CN1C(=S)S\C(=C/c2ccc(O)cc2)C1=O
Show InChI InChI=1S/C11H9NO2S2/c1-12-10(14)9(16-11(12)15)6-7-2-4-8(13)5-3-7/h2-6,13H,1H3/b9-6-
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n/an/a 1.40E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50275073
PNG
((Z)-3-Methyl-5-(1'-phenylethylidene)-2-thioxothiaz...)
Show SMILES Cn1c(O)c(sc1=S)C(=C)c1ccccc1
Show InChI InChI=1S/C12H11NOS2/c1-8(9-6-4-3-5-7-9)10-11(14)13(2)12(15)16-10/h3-7,14H,1H2,2H3
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n/an/a>3.00E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50275026
PNG
((Z)-5-(2'-Hydroxybenzylidene)-3-methyl-2-thioxothi...)
Show SMILES CN1C(=S)S\C(=C/c2ccccc2O)C1=O
Show InChI InChI=1S/C11H9NO2S2/c1-12-10(14)9(16-11(12)15)6-7-4-2-3-5-8(7)13/h2-6,13H,1H3/b9-6-
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PubMed
n/an/a 2.01E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50275028
PNG
((Z)-5-(4'-Methoxybenzylidene)-3-methyl-2-thioxothi...)
Show SMILES COc1ccc(\C=C2/SC(=S)N(C)C2=O)cc1
Show InChI InChI=1S/C12H11NO2S2/c1-13-11(14)10(17-12(13)16)7-8-3-5-9(15-2)6-4-8/h3-7H,1-2H3/b10-7-
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n/an/a 1.00E+3n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50275029
PNG
((Z)-5-(3'-Methoxybenzylidene)-3-methyl-2-thioxothi...)
Show SMILES COc1cccc(\C=C2/SC(=S)N(C)C2=O)c1
Show InChI InChI=1S/C12H11NO2S2/c1-13-11(14)10(17-12(13)16)7-8-4-3-5-9(6-8)15-2/h3-7H,1-2H3/b10-7-
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n/an/a 1.36E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50275067
PNG
((Z)-5-(3'-Fluorobenzylidene)-3-methyl-2-thioxothia...)
Show SMILES CN1C(=S)S\C(=C/c2cccc(F)c2)C1=O
Show InChI InChI=1S/C11H8FNOS2/c1-13-10(14)9(16-11(13)15)6-7-3-2-4-8(12)5-7/h2-6H,1H3/b9-6-
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PubMed
n/an/a 7.30E+3n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50241155
PNG
((Z)-5-(2'-Fluorobenzylidene)-2-thioxothiazolidin-4...)
Show SMILES Fc1ccccc1C=C1SC(S)=NC1=O
Show InChI InChI=1S/C10H6FNOS2/c11-7-4-2-1-3-6(7)5-8-9(13)12-10(14)15-8/h1-5H,(H,12,13,14)
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n/an/a>3.00E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50275068
PNG
((Z)-5-(2'-Fluorobenzylidene)-3-methyl-2-thioxothia...)
Show SMILES CN1C(=S)S\C(=C/c2ccccc2F)C1=O
Show InChI InChI=1S/C11H8FNOS2/c1-13-10(14)9(16-11(13)15)6-7-4-2-3-5-8(7)12/h2-6H,1H3/b9-6-
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n/an/a 1.18E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50181712
PNG
((Z)-5-(4'-Chlorobenzylidene)-3-methyl-2-thioxothia...)
Show SMILES CN1C(=S)S\C(=C/c2ccc(Cl)cc2)C1=O
Show InChI InChI=1S/C11H8ClNOS2/c1-13-10(14)9(16-11(13)15)6-7-2-4-8(12)5-3-7/h2-6H,1H3/b9-6-
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n/an/a 9.40E+3n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50181733
PNG
((Z)-3-Amino-5-(4'-chlorobenzylidene)-2-thioxothiaz...)
Show SMILES NN1C(=S)S\C(=C/c2ccc(Cl)cc2)C1=O
Show InChI InChI=1S/C10H7ClN2OS2/c11-7-3-1-6(2-4-7)5-8-9(14)13(12)10(15)16-8/h1-5H,12H2/b8-5-
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n/an/a 5.70E+3n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50241153
PNG
((Z)-5-(4'-Bromobenzylidene)-2-thioxothiazolidin-4-...)
Show SMILES SC1=NC(=O)C(S1)=Cc1ccc(Br)cc1
Show InChI InChI=1S/C10H6BrNOS2/c11-7-3-1-6(2-4-7)5-8-9(13)12-10(14)15-8/h1-5H,(H,12,13,14)
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n/an/a>3.00E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50274856
PNG
((Z)-5-(4'-Biphenylmethylene)-3-methyl-2-thioxothia...)
Show SMILES CN1C(=S)S\C(=C/c2ccc(cc2)-c2ccccc2)C1=O
Show InChI InChI=1S/C17H13NOS2/c1-18-16(19)15(21-17(18)20)11-12-7-9-14(10-8-12)13-5-3-2-4-6-13/h2-11H,1H3/b15-11-
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n/an/a 5.50E+3n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50274860
PNG
((Z)-5-Benzylidene-3-methyl-2-thioxothiazolidin-4-o...)
Show SMILES CN1C(=S)S\C(=C/c2ccccc2)C1=O
Show InChI InChI=1S/C11H9NOS2/c1-12-10(13)9(15-11(12)14)7-8-5-3-2-4-6-8/h2-7H,1H3/b9-7-
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n/an/a>3.00E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50275072
PNG
((Z)-5-(1'-Phenylethylidene)-2-thioxothiazolidin-4-...)
Show SMILES Oc1nc(S)sc1C(=C)c1ccccc1
Show InChI InChI=1S/C11H9NOS2/c1-7(8-5-3-2-4-6-8)9-10(13)12-11(14)15-9/h2-6,13H,1H2,(H,12,14)
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n/an/a 2.50E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50275025
PNG
((Z)-3-Amino-5-(4'-hydroxybenzylidene)-2-thioxothia...)
Show SMILES NN1C(=S)S\C(=C/c2ccc(O)cc2)C1=O
Show InChI InChI=1S/C10H8N2O2S2/c11-12-9(14)8(16-10(12)15)5-6-1-3-7(13)4-2-6/h1-5,13H,11H2/b8-5-
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n/an/a 1.01E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)

More data for this
Ligand-Target Pair