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There are 5 purchasable compounds for target: Apoptosis inhibitor survivin

Wt: 367.1
BDBM26673
Purchase
Wt: 227.6
BDBM50209186
Wt: 219.2
BDBM50209205
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Wt: 518.0
BDBM50209206
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Wt: 253.7
BDBM50024762
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 26673,50209186,50209205,50209206,50024762   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Baculoviral IAP repeat-containing protein 5


(Homo sapiens)
BDBM50024762
PNG
(CHEMBL395633)
Show SMILES Clc1cccc(Nc2ccc3ccccc3c2)c1
Show InChI InChI=1S/C16H12ClN/c17-14-6-3-7-15(11-14)18-16-9-8-12-4-1-2-5-13(12)10-16/h1-11,18H
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n/an/an/a<1.00E+4n/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins


Bioorg Med Chem Lett 17: 3122-9 (2007)

More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 5


(Homo sapiens)
BDBM50209186
PNG
(1-(4-chlorophenyl)-1H-indole | CHEMBL233218)
Show SMILES Clc1ccc(cc1)-n1ccc2ccccc12
Show InChI InChI=1S/C14H10ClN/c15-12-5-7-13(8-6-12)16-10-9-11-3-1-2-4-14(11)16/h1-10H
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n/an/an/a 5.00E+3n/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins


Bioorg Med Chem Lett 17: 3122-9 (2007)

More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 5


(Homo sapiens)
BDBM26673
PNG
(6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dih...)
Show SMILES Oc1ccc(Br)cc1-c1cc(-c2ccccc2)c(C#N)c(=O)[nH]1
Show InChI InChI=1S/C18H11BrN2O2/c19-12-6-7-17(22)14(8-12)16-9-13(11-4-2-1-3-5-11)15(10-20)18(23)21-16/h1-9,22H,(H,21,23)
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n/an/an/a 5.70E+3n/an/an/an/an/a



German University in Cairo

Curated by ChEMBL


Assay Description
Inhibition of survivin


Eur J Med Chem 45: 90-7 (2010)

More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 5


(Homo sapiens)
BDBM50209205
PNG
(CHEMBL277554 | N-(4-methylpyridin-2-yl)piperidine-...)
Show SMILES Cc1ccnc(NC(=O)C2CCNCC2)c1
Show InChI InChI=1S/C12H17N3O/c1-9-2-7-14-11(8-9)15-12(16)10-3-5-13-6-4-10/h2,7-8,10,13H,3-6H2,1H3,(H,14,15,16)
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n/an/an/a 1.30E+5n/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins


Bioorg Med Chem Lett 17: 3122-9 (2007)

More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 5


(Homo sapiens)
BDBM50209206
PNG
((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodopheny...)
Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1
Show InChI InChI=1S/C17H12I2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3
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PubMed
n/an/an/a 8.00E+3n/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins


Bioorg Med Chem Lett 17: 3122-9 (2007)

More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 5


(Homo sapiens)
BDBM26673
PNG
(6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dih...)
Show SMILES Oc1ccc(Br)cc1-c1cc(-c2ccccc2)c(C#N)c(=O)[nH]1
Show InChI InChI=1S/C18H11BrN2O2/c19-12-6-7-17(22)14(8-12)16-9-13(11-4-2-1-3-5-11)15(10-20)18(23)21-16/h1-9,22H,(H,21,23)
PDB
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PC cid
PC sid
PDB
UniChem

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Article
PubMed
n/an/an/a 5.00E+3n/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins


Bioorg Med Chem Lett 17: 3122-9 (2007)

More data for this
Ligand-Target Pair